Discovery of Novel Celastrol Derivatives as Hsp90–Cdc37 Interaction Disruptors with Antitumor Activity by Na Li (6550)

“…Among all the target compounds, <b>41</b> was screened with superior antiproliferative activity on related cancer cells (IC₅₀: 0.41–0.94 μM) and <b>41</b> could decrease the level of the Hsp90–Cdc37 complex in A549 cells. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Dental pain prevalence among health care personnel by Ludmilla Awad Barcellos (10477586)

“…<div><p>ABSTRACT BACKGROUND AND OBJECTIVES: Dental pain is a major reason for looking for dental services. …”

MMR activities in the APE and hMSH6 expressing cells by In-Youb Chang (10654)

“…The repair efficiency was calculated as the percentage of decrease in the mixed-color colonies. The values are a mean ± SD from three separate experiments. …”

Effects of variation in pDC number and activation status. by Gennady Bocharov (67777)

“…<p>(A) Virus kinetics in spleen following infection with low (5×10¹ pfu), intermediate (5×10³ pfu) and high (5×10⁵ pfu) dose infections under conditions of varying pDC numbers per spleen. …”

Datasheet1_Trends in hypertension and hypertension treatment in primary care in general practices in Germany between 2013 and 2022.pdf by Karel Kostev (2577346)

“…After adjusting for covariates, there was a significant decrease in the number of patients diagnosed with hypertension (beta coefficient = −7.91, p-value < 0.001) and treated with any antihypertensive drug per practice per year between 2013 and 2022 (beta coefficient = −5.40, p-value < 0.001).…”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Supplementary Material for: Effects of Simvastatin on inflammatory response and biological behavior of adamantinomatous craniopharyngioma by Li W. (3610583)

“…Western blot analysis demonstrated SIM inhibited nuclear factor-kappa B (NF-κB) p65 activation expression while promoted the expressions of Cl-caspase-3 and P38 MAPK. CCK8 assay indicated a decrease in ACP cell activity upon SIM treatment. …”

The viability and morphology of IL-13- or IL-13+ cell cultures. by Andrea Stadnikova (3929546)

“…Cell viability data are presented in a vertical scatter plot graph with line indicating mean. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Constraint on the eclogite age of the Sanbagawa metamorphic rocks in central Shikoku, Japan by Shogo Aoki (6440666)

“…It is likely that the older unit was subducted into a depth of over 50 km and stagnated until the younger unit was subducted to the same depth. …”

IL-1β, IL-6, and RANTES as Biomarkers of Chikungunya Severity by Lisa F. P. Ng (252501)

“…Statistical analysis showed that an increase in IL-1β, IL-6 and a decrease in RANTES were associated with disease severity.…”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Primer pairs for RT-qPCR. by Yoichi Kurokawa (22290520)

“…Treatment with 1 μM exogenous prooxidants (1,2,4-benzenetriol or 1,4-naphthoquinone) resulted in a significant increase (>50-fold) in the expression of several lncRNAs, including Snhg4, Kcnq1ot1, Rmst, Neat1, Gt(ROSA)26Sor, and Peg13. …”

Factor of change of pO (ΔpO) segregated with respect to the initial median pO by Bernardino Clavo (3925)

“…<p><b>Copyright information:</b></p><p>Taken from "Ozone Therapy for Tumor Oxygenation: a Pilot Study"</p><p>Evidence-based Complementary and Alternative Medicine 2004;1(1):93-98.…”

Occult Urinary Incontinence Treatment: Systematic Review and Meta-analysis-Brazilian Guidelines by Priscila Katsumi Matsuoka (6624389)

“…Methods We have performed a systematic review of articles published in the PubMed, Cochrane Library, and Lilacs databases until March 31, 2016. …”

Image_1_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

Image_5_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

The activity of TRPV1 is dependent on phosphoinositides. by Hae-Jin Kweon (525019)

“…<p>(A) Confocal images of cells expressing PJ-Dead (<i>top</i>), PJ-Sac (<i>middle</i>), INPP5E (<i>middle</i>), or PJ (<i>bottom</i>) with LDR and respective biosensors for PI(4)P (Osh1-PH-GFP) or PI(4,5)P₂ (PLCδ1-PH-GFP). …”