An in vitro anti-inflammatory effect of Thai propolis in human dental pulp cells by Nutthapong KANTRONG (16029384)

“…Incubation with various non-toxic concentrations of the propolis extract significantly inhibited upregulated COX-2 mRNA and protein expressions upon treatment with IL-1β (p<0.05), resulting in a significant decrease in elevated PGE2 levels (p<0.05). …”

DataSheet1_Antisense targeting of FOXP3+ Tregs to boost anti-tumor immunity.docx by Tatiana Akimova (345316)

“…In murine studies, we observed a significant inhibition of tumor growth, while 13.6% (MC38) to 22% (TC1) of tumors were completely resorbed, in conjunction with ~50% decrease of Foxp3 mRNA by qPCR and decreased numbers of intratumoral Tregs. …”

Analysis of fitness multiplexed cell lines and identification of cell line-specific fitness phenotypes. by Daniel F. Gilbert (193637)

“…Cell fitness phenotypes were selected from ranked mean values with small values indicating strong decrease in fitness. 25, 50 and 75 top-ranking fitness phenotypes were selected for both cell lines as well as for randomly generated values from all fitness indicators and the intersection (in %) of phenotypes identified in two (<b>A</b>.) and three (<b>B</b>.) channels was calculated as measure of hit confirmation. …”

STAD-2 reduces viability of <i>P</i>. <i>falciparum in vitro</i>. by Briana R. Flaherty (744995)

“…(<b>B</b>) Synchronous iRBC were treated with 1 μM STAD-2 or STAD-2 scramble, and parasitemia was determined by flow cytometry at 24, 48 and 72 hours post-treatment. A significant decrease in parasitemia was seen with STAD-2 treatment of both ring- and late-stage iRBC (2way ANOVA, p<0.001, n = 3, mean ± S.E., red = STAD-2/late, blue = STAD-2/ring, orange = STAD-2 scramble/late, green = STAD-2 scramble/ring). …”

Percent of CSCs in MCF-7 human breast cancer cells treated with hyperthermia and metformin. by Hyemi Lee (342537)

“…The numbers of spheres with diameter >50 µm were counted under a microscope. The combinations of heating and metformin were statistically more effective than metformin alone.…”

Ocean Acidification Affects the Phyto-Zoo Plankton Trophic Transfer Efficiency by Gemma Cripps (2615005)

“…Under the combined indirect+direct exposure, carbon trophic transfer efficiency from phytoplankton-to-zooplankton declined to < 50% of control populations, with a commensurate decrease in recruitment. …”

Influence of <i>k</i>₁ on the homeostatic behavior of the m7 ping-pong controller when <i>E</i>₁ binds first to free enzyme <i>Ez</i>. by Qaiser Waheed (5095328)

“…(c) A decrease of <i>k</i>₆ from 5.0 to 1.0 while <i>k</i>₁ is kept at 100.0 gives a general improvement of the homeostatic performance of the ping-pong controller, except for the higher end <i>k</i>₅ range between 900–1000, where <i>A</i>_<i>ss</i> becomes constant (indicated by the red circle). …”

Synthesis, Structures, and Kinetics of Mixed-Donor Amido−Amino−Siloxo Ligands from Symmetrical Diamidosilyl Ether Ligands via a Retro-Brook Rearrangement by Farzad Haftbaradaran (2456386)

“…Deprotonation of the new (R = propyl, 3,5-Me₂Ph) and previously prepared (R = 2,4,6-Me₃Ph, 2,6-<i>ⁱ</i>Pr₂Ph, 3,5-(CF₃)₂Ph) symmetrical diamidosilyl ether ligand precursors {[RNHSiMe₂]₂O} with 2 equiv of <i>ⁿ</i>BuLi in THF resulted in a new class of mixed-donor amido−amino−siloxo ligands of the form {RNLiSiMe₂N(R)SiMe₂OLi} (R= propyl (<b>1c</b>), 3,5-Me₂Ph (<b>2c</b>), 2,4,6-Me₃Ph (<b>3c</b>), 2,6-<i>ⁱ</i>Pr₂Ph (<b>4c</b>), 3,5-(CF₃)₂Ph (<b>5c</b>)) in one-step and high yield via a retro-Brook-type rearrangement mechanism. …”

Image_3_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_2_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_4_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.JPEG by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_1_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.JPEG by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_3_RETRACTED: Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_2_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_2_RETRACTED: Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_1_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.JPEG by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_4_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.JPEG by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_4_RETRACTED: Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.JPEG by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_3_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_1_RETRACTED: Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.JPEG by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”