Table_4_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.DOCX by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Table_2_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.DOCX by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Table_3_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.XLSX by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Image_1_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.TIF by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Table_1_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.DOCX by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Image_3_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.TIF by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Image_2_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.TIF by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Image_4_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.TIFF by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

LOH at <i>KSR1</i> affects cellular lipid profiles, intracellular FLC concentrations, drug efflux, and sterol levels. by Pétra Vande Zande (17628246)

Fig 3 - by Sumei Luo (9570740)

Data_Sheet_1_Functional Change of Effector Tumor-Infiltrating CCR5+CD38+HLA-DR+CD8+ T Cells in Glioma Microenvironment.docx by Pin-Yuan Chen (391703)

“…However, little is known about the characteristics of peripheral and tumor-infiltrating CD8⁺ T cells in patients with glioma. In this study, we examined the level of CD8⁺ T-cell activation in a group of 143 patients with glioma and determined that peripheral CD3⁺ T cells decreased in accordance with disease severity. …”

Results in terms of accuracy (%) and response time (ms). by Talia L. Retter (16520742)

DN-Rab10 inhibits caffeine induced increased activity but not mortality. by Scott M. Vanderwerf (785324)

Hematoxylin and eosin (H&E) staining, Sirius Red staining, and Oil Red staining of liver tissues from mice in each group after 8 weeks of treatment with either vehicle or Kylo-0603... by Xueqin lu (22250795)

Down-regulation of HCP5 inhibits cell proliferation, migration, and invasion through regulating EPHA7 by competitively binding miR-101 in osteosarcoma by Yangmao Tu (10461966)

“…Long non-coding RNAs (lncRNAs) have been reported to be associated with tumorigenesis and metastasis. In this study, we investigated the expression and roles of lncRNA human histocompatibility leukocyte antigen (HLA) complex P5 (HCP5) in OS, aiming to provide a novel molecular mechanism for OS. …”

Main effect of categorization listening (red) and Effect 2 of interaction of presentation rate and word processing (blue) overlaid on coronal slices of the group's mean brain (neur... by Tömme Noesselt (55355)

Video 5_Retrospective self-gating for single-petal rosette trajectory in 2D lung imaging.avi by Hanna Frantz (12195152)

“…The same was found for SNR, where the highest increase was found for a temporal resolution of 75 ms.</p>Conclusion<p>Exploiting the higher efficiency in k-space sampling of the full-petal SPR for image based self-gating can be a means of decreasing temporal resolution.…”

Lipid Droplet-Binding Protein TIP47 Regulates Hepatitis C Virus RNA Replication through Interaction with the Viral NS5A Protein by Dorothee A. Vogt (247917)

“…To identify host proteins that interact with NS5A, we performed a yeast two-hybrid screen with the N-terminus of NS5A (amino acids 1–31), a well-studied α-helical domain important for the membrane tethering of NS5A. …”

Nrf2 endogenous expression is high in PMNs and increases in response to SFN and zymosan. by Doumet Georges Helou (7255823)

HE staining and Masson staining images and analysis of tumor tissue after ablation. by Qing-Gang Li (273341)