Decreased α-cell mass and early structural alterations of the exocrine pancreas in patients with type 1 diabetes: An analysis based on the nPOD repository by Fidéline Bonnet-Serrano (4782546)

“…The β- and α-cell masses were calculated in the 66 patients and the 50 controls for which the pancreas weight was available. …”

Video example of a boundary vector cell. by Lear Cohen (15353793)

Elimination of the MRC rescues the prophase I delay due to constitutive Rad51 activation, while decreasing spore viability and increasing MI nondisjunction. by Andrew Ziesel (9422868)

Outstanding impact of Azospirillum brasilense strains Ab-V5 and Ab-V6 on the Brazilian agriculture: Lessons that farmers are receptive to adopt new microbial inoculants by Mariana Sanches Santos (10378494)

“…Several research groups in Brazil presented impressive results of increases in root growth, biomass production, grain yield, uptake of nutrients and water, and increased tolerance to abiotic stresses due to the inoculation with Ab-V5 and Ab-V6. In this review, we gathered the results obtained so far in one decade with these two strains in several grasses and legume crops, confirming their versatility and indicating that with convincing, reliable, and consistent results, the Brazilian farmers are receptive to the adoption of new sustainable technologies based on microorganisms.…”

Illustration of the difference between the IC50 value assessed directly from experimental data and model-based deconvolution of mechanisms explaining downstream inhibition. by Jennifer L. Wilson (6061124)

“…In the proposed modeling framework, it is possible to separate effects on a specific cell type, from propagated effects, such as loss of upstream progenitors. …”

Cell cycle accumulation at G2/M in MTDH knockdown Hec50co cells at 24 hours after LBH589 or LBH589 and TRAIL treatment. by Xiangbing Meng (200278)

“…<p>(A) Cell cycle profiles were determined in control or MTDH knockdown Hec50co cells at 24 hours after treatment with 20 nM LBH589, 25 ng/ml TRAIL, or LBH589 and TRAIL in combination. …”

Oxidation of L-[1-¹⁴C]Cys as a percentage of dose in enterally fed piglets receiving graded levels of Cys and 0.25 g kg^-1 d^-1 Met. by Anna K. Shoveller (6208457)

Hydrogen-Bonding Trends in a Bithiophene with 3- and/or 4‑Pyridyl Substituents by Alison M. Costello (16456762)

“…We found that with the 5-(3-pyridyl)-5′-(4-pyridyl)-isomer, the 4-pyridyl ring interacted with electrophiles and protons more strongly. …”

Hydrogen-Bonding Trends in a Bithiophene with 3- and/or 4‑Pyridyl Substituents by Alison M. Costello (16456762)

“…We found that with the 5-(3-pyridyl)-5′-(4-pyridyl)-isomer, the 4-pyridyl ring interacted with electrophiles and protons more strongly. …”

Tryptophan and metabolite alterations in response to a control diet or a diet containing MCOA. by Natalie E. Diether (16705804)

<i>In vitro</i> drug susceptibility of a panel of recent clinical <i>L</i>. <i>infantum</i> isolates against antileishmanial reference drugs in THP-1, bone-marrow derived macrophag... by Sarah Hendrickx (321143)

Preformed biofilm. by Rodrigo Rollin-Pinheiro (239450)

Biofilm formation. by Rodrigo Rollin-Pinheiro (239450)

Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments by Animesh Gopal (18521180)

“…Polypropylene (PP) is widely used in commodity applications owing to its chemical stability, mechanical properties and low cost. However, almost 50% of the produced PP ends up as postconsumer waste (PCW) within a short period of usage. …”

Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments by Animesh Gopal (18521180)

“…Polypropylene (PP) is widely used in commodity applications owing to its chemical stability, mechanical properties and low cost. However, almost 50% of the produced PP ends up as postconsumer waste (PCW) within a short period of usage. …”

ET-26 hydrochloride (ET-26 HCl) has similar hemodynamic stability to that of etomidate in normal and uncontrolled hemorrhagic shock (UHS) rats by Bin Wang (30851)

“…Rats in the UHS group underwent experimentally induced UHS with a target arterial pressure of 40 mmHg for 1 hour, followed by administration of an ED₅₀ dose of one of the experimental agents. …”

Benchmarking the Predictive Power of Ligand Efficiency Indices in QSAR by Isidro Cortes-Ciriano (1450789)

“…Two studies published in this journal showed that higher predictive power on external molecules can be achieved by using ligand efficiency indices as the dependent variable instead of a metric of potency (IC₅₀) or binding affinity (<i>K</i>_<i>i</i>). …”

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) by Ariel L. Burgio (15069256)

“…Our studies revealed <b>SLB1122168</b> (<b>33p</b>), which is a potent inhibitor (IC₅₀ = 94 ± 6 nM) of Spns2-mediated S1P release. …”

Homologs of 16p12.1 genes contribute towards neurodevelopmental defects through weak genetic interactions and combined independent effects. by Lucilla Pizzo (2735491)

The effect of alexidine, amorolfine and olorofim on <i>S</i>. <i>aurantiacum</i> morphology and cell parameters. by Rodrigo Rollin-Pinheiro (239450)