EGC inhibits breast cancer growth and LDH-A expression <i>in vivo</i>. by Zhiyu Wang (282312)

“…The results showed that in both breast cancer xenografts, the expression levels of LDH-A, Ki67 and HIF-1α were decreased in comparison to that in control groups, while apoptosis ratio was elevated in EGC-treated tumor samples detected by TUNEL method; (C) Western blotting analysis showed that the expression of HIF-1α and LDH-A in EGC-treated tumor samples were significantly decreased in comparison with control groups (left panel). …”

Link prediction in 25%, 50% and 75% of the links in networks constructed from all the words in tweets of the emo-net^<i>a</i>, emo-net^<i>b</i>, emo-net<sup><i>... by Sanda Martinčić-Ipšić (4256092)

Comparison of staining efficacy of samples acquired using BD LSRFortessa flow cytometer. by Karine Sonzogni-Desautels (6490919)

“…Increasing levels of parasite burdens (counts in Y axis) show decreasing antibody staining efficacy: > 90% (C); < 90% but > 50% (D); < 50% but > 25% (E); < 25% (F).…”

Improving osteoarthritis care by digital means - Effects of a digital self-management program after 24- or 48-weeks of treatment by Leif E. Dahlberg (7405928)

“…For the 24-week sub-sample, pain NRS decreased monthly by -0.43 units (95% CI -0.51, -0.35, mean knee pain from 5.6 to 3.1, and hip pain from 5.9 to 3.8) and 30CST repetitions increased monthly by 0.76 repetitions (95% CI 0.64, 0.89 mean for knee from 10.0 to 14.3, and for hip from 10.9 to 14.8). …”

Additional Analysis of visually induced calcium transients in Fig 6. by Maureen M. Sampson (9322886)

“…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …”

Priapism in Sickle mice is due to unrestrained cGMP/PDE5 function. by Trinity J. Bivalacqua (429540)

Single simulation illustrating trough-max and the switch to peak-max. by Austin E. Soplata (4676017)

The relationship of lung function with ambient temperature by Joseph M. Collaco (195530)

“…The effect was similar in both cohorts with a 0.71% and 0.59% predicted FEV₁ decrease for every 10°F increase in mean temperature in the NHANES III and NHANES 2007–2012 cohorts, respectively. …”

Morphometric analysis results of bone matrix staining after 5 days chemical treatments. by Jessica Aceto (752869)

“…<p>The distances are measured in pixels. Mean ± SD and t-test analysis were calculated for each measure on at least 20 individuals. * <i>p <</i> 0.05, ** <i>p <</i> 0.01 and ***<i>p <</i> 0.001. …”

Estimation of A3G and Vif production rates. by Iraj Hosseini (184245)

“…All the results in (A) and (B) are obtained for <i>k_A3G.HIV</i> = 50 µM⁻¹/hr. …”

A Gain-Of-Function Mutation in the <i>Plcg2</i> Gene Protects Mice from <i>Helicobacter felis</i>-Induced Gastric MALT Lymphoma by Jennifer Gossmann (3181209)

“…Heterozygous BALB/c <i>Plcg2</i>^{<i>Ali5/+</i>} and wildtype (WT) mice were infected with <i>Helicobacter felis (H</i>. …”

(a, b). The statistical error analyses for the models using the same dataset. by Fahd Saeed Alakbari (10701871)

High levels of extracellular L-Cystine promoted the L-Cystine-L-Glutamate antiport via xCT and decreased the intracellular GSH/GSSG ratio in monocyte under the amino acid environme... by Eiji Kakazu (209203)

Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 by Marta E. Capala (652765)

“…Downregulation of SAM50 also impaired the proliferation and replating capacity of BCR-ABL-expressing cells, again associated with a decreased mitochondrial membrane potential. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Bootstrapped LIWC positive word ratio (LWPR) around the hit date for each hurricane and location. by Krishna Bathina (12883820)

Aflatoxin B₁ Negatively Regulates Wnt/β-Catenin Signaling Pathway through Activating miR-33a by Yi Fang (287944)

“…The level of miR-33a was up-regulated in hepatocellular carcinoma (HCC) cells treated with AFB₁, while in the same cells causing the decrease in β-catenin expression when treated at their IC₅₀ values. miR-33a, specifically miR-33a-5p, was demonstrated to down-regulate the expression of β-catenin, affect the β-catenin pathway, and inhibit cell growth. …”