Ouabain block of the Na⁺/K⁺ pump switches Purkinje cell activity out of the trimodal firing pattern and into a continuous burst mode. by Michael D. Forrest (292801)

“…In this case, the only deflections observed are those of the Ca²⁺ spikes that have travelled into the soma from the dendritic arborisation (<i>E</i>, <i>I</i>). <i>Panel A scaling is encoded in the first scale bar (50 mV, 50 s). …”

Table 1_Time course of organ and hematological response to complement blockage in transplant-associated thrombotic microangiopathy after allogeneic hematopoietic stem cell transpla... by Tatiana A. Rudakova (20945432)

“…Secondary endpoints included the cumulative incidence of a 25% decrease in serum lactate dehydrogenase levels and to the limit of the normal range for age from the date of the initiation of eculizumab, the cumulative incidence of a 50% increase in platelet count or stable platelet levels ≥ 20×10⁹/l was 74% (95% CI, 32–92) with median time 21 days (range: 1–104), cumulative incidence of platelet level ≥ 50×10⁹/l, and 1 year from the date of the initiation of eculizumab.…”

Image_1_Biosynthesis of Silver Nanoparticles by Marine Actinobacterium Nocardiopsis dassonvillei and Exploring Their Therapeutic Potentials.jpg by Maha A. Khalil (11454121)

“…In vitro studies using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay revealed a concentration-dependent decrease in cell viability when CaCo2 cells were exposed to Bio-AgNPs. …”

The effect of (A) mean sequencing depth (genome coverage) and (B) average number of nucleotide differences per site (<i>π</i>) on accuracy of genetic similarity estimates in simula... by Kevin D. Murray (759583)

Simplified diagrammatic representation of our mathematical model. by Cyrill A. Rentsch (117042)

“…A more detailed version of this figure is provided by the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056327#pone.0056327.s001" target="_blank"><b>Figure S1</b></a> of the supplemental material.…”

Effect of PMI on cytoskeletal proteins. by Jeffrey A. Blair (3178230)

“…Scale bars = 50 μm. (B) However, by Western blot, while the proteins actin and GAPDH show no correlation with PMI times, detectable tubulin levels decrease significantly after a PMI of 22 h. …”

The canonical pathway of NF-κB activation is required for TNF-α and IL-1β stimulated eotaxin and MCP-1 gene expression in gingival fibroblasts. by Elisabeth A. Boström (495490)

“…<p><b>(A)</b> Time-dependent decrease of IκBα protein in gingival fibroblasts exposed to TNF-α (50 ng/ml) and IL-1β (100 pg/ml) cultured for 5, 10, 15 and 30 min. …”

Timeline depicting the harvest history of sage-grouse from 1870s–2019 stratified by sage-grouse Management Zone and greater and Gunnison sage-grouse populations. by Jonathan B. Dinkins (11478180)

Table 4_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

Table 5_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

Table1_Alterations in circulating lipidomic profile in patients with type 2 diabetes with or without non-alcoholic fatty liver disease.docx by Assim A. Alfadda (9674998)

μCT analysis of extra-osseous extension of primary osteosarcoma. by Heather A. Cole (571670)

EWS/FLI-1 siRNA and R1507 block Ewing's sarcoma cell proliferation by inhibiting a shared pathway: phosphorylation of IGF-1R and Akt. by Helen J. Huang (201553)

Additional file 2 of Single-cell profiling reveals periosteal signatures of impaired periosteal cells proliferation in a drill-hole model of type 2 diabetes by Xing Ji (3096735)

“…Effect of FGL2 on Osteoblast Proliferation Under Normal and High Glucose Conditions. A. Osteoblasts were treated with vehicle or varying concentrations of FGL2 (50, 200 ng/mL) under normal (vehicle) and high glucose (4.5 mg/mL) conditions, and relative cell proliferation was assessed after 48 h to compare the effects under these different conditions. …”

Histomorphometry of cancellous bone in tibiotarsus proximal part of 42 days-old broiler chickens fed soybean meal (SBM) or chickpea seeds (CPS) as a primary protein source. by Siemowit Muszyński (4112557)

“…A significant decrease of mean trabecular space (Tb.Sp mean) was additionally observed in the CPS group.…”

DataSheet1_Phytochemical analysis and anticancer effect of Camellia oleifera bud ethanol extract in non-small cell lung cancer A549 cells.PDF by Jingming Niu (17268094)

“…For anticancer activity, C. oleifera bud EE had remarkable cytotoxic effect on non-small cell lung cancer A549 (IC₅₀: 57.53 ± 1.54 μg/mL) and NCI-H1299 (IC₅₀: 131.67 ± 4.32 μg/mL) cells, while showed lower cytotoxicity on non-cancerous MRC-5 (IC₅₀ > 320 μg/mL) and L929 (IC₅₀: 179.84 ± 1.08 μg/mL) cells. …”

The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2... by Da Cunha, Amanda Ramos

“…Importance: Lip, oral, and pharyngeal cancers are important contributors to cancer burden worldwide, and a comprehensive evaluation of their burden globally, regionally, and nationally is crucial for effective policy planning. …”
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Neural network classifiers can distinguish states which differ in either activity or correlations. by Nicholas A. Frost (10739821)

“…In this manner, half the neurons increased their activity in “State B” compared to “State A”; the other half decreased. The proportion of activity transferred was determined by randomly drawing a number with an upper bound ranging from 5% to 50%. …”

Immunofluorescence analysis of lumbar spinal cord sections at 3 months after spinal cord transection. by Jose A. Corleto (841164)

“…<b>(G, H, I)</b>- Quantitative densitometric analysis of GAD65, GFAP and IB1 immunoreactivity showed a decrease in GAD65 and increase in GFAP and IB1 staining in TSCT animals if compared to naïve controls (t-test ***-p<0.001; scale bar: A, B: 50 μm C, D, E, F: 200 μm).…”

Does the Introgression of Bt Gene Affect Physiological Cotton Response to Water Deficit? by C.A. ROSOLEM (6676022)

“…The experiment was conducted in a greenhouse, where the cotton cultivars FMT 705, FMT 709 and IMACD 8276, with and without the Bt gene, were grown under two water regimens: 100% and 50% (moderate water deficit) of available soil water. …”