IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors by Alexandra Cousido-Siah (777034)

“…Next, by means of IC₅₀ measurements, X-ray crystallography, WaterMap analysis, and advanced binding free energy calculations with a quantum-mechanical (QM) approach, we have studied their structure–activity relationship (SAR) against both enzymes. …”

A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population by Victoria L. Herrera (383897)

“…The <i>ATP1A1</i> promoter containing the 12T-insertion exhibited decreased transcriptional activity in in vitro reporter-assay systems, indicating decreased α1Na,K-ATPase expression with the 12T-insertion, compared with the 12T-deletion <i>ATP1A1</i> promoter. …”

The pennogenyl saponins treatment decreased HeLa cells viability. by Justyna Stefanowicz-Hajduk (785885)

Thy1-p45 transgenic mice have decreased retraction of CST fibers and improved functional recovery following SCI compared to their WT littermates. by Tsung-Chang Sung (436234)

Results of peptide toxicity of each diet. by Fatima Dikhanbayeva (11501962)

“…<p>Values are given as mean ± SD for a total of 50 animals. Control group (I) - 0.295 nm, Curd mass (II)– 0.122 nm, Curd mass with flaxseed flour (III)– 0.113 nm, curd mass with celery root powder (IV) - 0.114 nm, Curd mass with bee bread (V)– 0.127 nm. …”

Compound 1 decreased the ΔΨm level of HepG-2 cells. by Jing Zhang (23775)

BpiB09 affects the QS-dependent pyocyanin production, <i>C. elegans</i> paralysis in PAO1 and decreases AHL response in <i>A. tumefaciens</i> AHL reporter strain. by Patrick Bijtenhoorn (199146)

“…<p><b>A</b>) Decreased pyocyanin production. OD₅₂₀ of pyocyanin extracts from culture supernatants of <i>P. aeruginosa</i> carrying pBBR1MCS-5::<i>bpiB09</i> and empty pBBR1MCS-5. …”

<i>clec-4(ok2050)</i> and <i>clec-4(ya1)</i> decrease <i>C</i>. <i>elegans</i> feeding leading to a reduced bacterial load. by Barbara Pees (3313560)

The results of assay of blood serum biochemical parameters after experiment. by Fatima Dikhanbayeva (11501962)

“…*Values are given as mean ± SD for a total of 50 animals. p<0, 05 versus mice fed regular diet.…”

Data_Sheet_1_Concurrent use of statins decreases major bleeding and intracerebral hemorrhage in non-valvular atrial fibrillation patients taking direct oral anticoagulants—A nation... by Hsin-Hsu Wu (440386)

“…</p>Results<p>50,854 (56.0%) of them were male with a mean age of 74.9 (SD, 10.4) years. …”

Top 50 genes whose expression is most decreased during post-eyelid opening WT corneal maturation between PN11 and PN56. by Doreswamy Kenchegowda (135193)

Population dynamics modeling of split^50cM <i>ClvR</i> V1 introduced at a 50% release, with fitness cost per allele varying from 0–15%. by Georg Oberhofer (3401438)

Lichen species richness (LSR) model summarized by distance class from the DMTS haul road in CAKR. by Peter N. Neitlich (4034300)

Subjects:

Nonmetric multidimensional scaling ordination of lichen plots at distances 10 m through 4000 m from the DMTS haul road in Cape Krusenstern National Monument, Alaska. by Peter N. Neitlich (4034300)

Subjects:

Photos of <i>Hylocomium splendens</i> moss and <i>Peltigera</i> sp. lichen from 10 m vs 4000 m away from the DMTS haul road in Cape Krusenstern National Monument, Alaska. by Peter N. Neitlich (4034300)

Subjects:

Decreased expression levels of SPI-1 genes in <i>bipA</i>-deleted strain at 20°C. by Eunsil Choi (8271039)

Percentage of rewards obtained (A-F), call rate (GH), and session duration (IJ) in rats grouped by performance in USV-training. by Agnieszka D. Wardak (17941139)

Patterns of disease knowledge according to number of participants giving correct answers to each individual Chinese IBD-KID2 item, with vertical line representing 50% of the overal... by HaiQun Huang (20978503)

Decreased macrophage recruitment correlates with decreased angiogenesis. by Johanna R. Reed (306158)

“…<p>A) Quantification of BrdU incorporation demonstrates that decreased macrophage infiltration does not significantly correlate with a change in epithelial cell proliferation (N.S. = not significant). …”

How the variation in inhibitor concentration throughout one day affects the value of IC₅₀/(IC₅₀ + [R]) for different Abl1 inhibitors. by J. Roadnight Sheehan (20141887)