Effects of PACAPs and/or oxidative stress on NFAT4, calcineurin expression and activity in chondrifying cells. by Tamás Juhász (195396)

“…<p>PACAP 1-38 at 100 nM, PACAP 6-38 at 10 µM were applied continuously from day 1. …”

Correlation of Cervical Cancer Mortality with Fertility, Access to Health Care and Socioeconomic Indicators by Diama Bhadra Vale (6879314)

“…In the multivariate analysis, only fertility rate was significantly associated with the CC mortality rate (coefficient of correlation: 9.38; 95% confidence interval [CI]: 5.16-13.59). Conclusion A decrease in the fertility rate, as expected when the level of development of the regions increases, is related to a decrease in the mortality rate of CC. …”

Delayed degeneration of striatal neurons following icv GA administration. by Silvia Olivera-Bravo (349736)

“…<b>D:</b> Time course of number of striatal NeuN positive neurons showing a significant decrease at P21 and P45 in GA-injected animals as compared to controls. …”

Body image perception and satisfaction in university students by Ingrid Ludimila Bastos Lôbo (10422415)

“…<div><p>Abstract Body image represents the mental perception of body shapes and is a multifactorial structure that includes psychological, physical and emotional elements. …”

Heat map analysis of selected peptides. by Sayani Dasgupta (104387)

“…Bright red indicates peptides that were elevated ≥100% (ratio ≥2.00). The three groups in the heat map indicated by lines and numbers on the left margin indicate peptides which showed a large or partial decrease (set 1), little or no change (set 2), or a large increase (set 3) in response to the proteasome inhibitors. …”

Partial unwinding of backbone modified DNA substrates by BACH1-WT helicase by Rigu Gupta (22923)

“…As the dsDNA is unwound, the dye molecules are displaced (open ovals) which is measured by a decrease in the amount of fluorescence. In Scheme 1, the unmodified DNA substrate is fully unwound by the helicase, resulting in a maximal change in fluorescence. …”

Image1_Pharmacokinetics, Mass Balance, Excretion, and Tissue Distribution of Plasmalogen Precursor PPI-1011.jpg by Tara Smith (2558311)

“…Further tissue distribution was examined using quantitative whole-body autoradiography after both single and repeat daily doses at 100 mg/kg/day. Non-compartmental analysis showed that following a single dose, PPI-1011 exhibited peak levels between 6 and 12 h but also a long half-life with mean t_1/2 of 40 h. …”

Table2_Pharmacokinetics, Mass Balance, Excretion, and Tissue Distribution of Plasmalogen Precursor PPI-1011.pdf by Tara Smith (2558311)

“…Further tissue distribution was examined using quantitative whole-body autoradiography after both single and repeat daily doses at 100 mg/kg/day. Non-compartmental analysis showed that following a single dose, PPI-1011 exhibited peak levels between 6 and 12 h but also a long half-life with mean t_1/2 of 40 h. …”

Table1_Pharmacokinetics, Mass Balance, Excretion, and Tissue Distribution of Plasmalogen Precursor PPI-1011.pdf by Tara Smith (2558311)

“…Further tissue distribution was examined using quantitative whole-body autoradiography after both single and repeat daily doses at 100 mg/kg/day. Non-compartmental analysis showed that following a single dose, PPI-1011 exhibited peak levels between 6 and 12 h but also a long half-life with mean t_1/2 of 40 h. …”

Image2_Pharmacokinetics, Mass Balance, Excretion, and Tissue Distribution of Plasmalogen Precursor PPI-1011.jpg by Tara Smith (2558311)

“…Further tissue distribution was examined using quantitative whole-body autoradiography after both single and repeat daily doses at 100 mg/kg/day. Non-compartmental analysis showed that following a single dose, PPI-1011 exhibited peak levels between 6 and 12 h but also a long half-life with mean t_1/2 of 40 h. …”

Fig 11 - by Maike Stegen (8578665)

“…Actin β at approx. 40 kDa (molecular weight 43 kDa) was used as a reference on a stripped membrane. Stimulation with 100 nM PMA led to a distinct decrease in GRK6 protein expression. …”

Penile cancer trends and economic burden in the Brazilian public health system by Fernando Korkes (5910167)

“…Conclusion: Despite the decrease in admissions, penile cancer still imposes a significant economic and social burden to the Brazilian population and the Public Health System.…”

cAMP dynamics in adult mouse ventricular Epac1-camps expressing cardiomyocytes upon treatment with cAMP elevating agents and PDE4 inhibition. by Julia U. Sprenger (3387719)

“…<b>(C)</b> Representative FRET traces from Epac1-camps cardiomyocytes stimulated with the β-AR agonist isoproterenol (ISO, 100 nM) or <b>(E)</b> with the direct AC activator forskolin (10 μM) leading to an increase of cAMP visualized as a decrease in the FRET ratio. …”

SR Ca²⁺ uptake, Ca²⁺ signaling proteins, and transcriptional factors. by Mei Hua Gao (458915)

“…<b>Lower:</b> Expression of AC6mut decreased SERCA2a affinity for Ca²⁺. The effective concentration of Ca²⁺ for 50% maximal effect (EC₅₀) was calculated from the initial ATP-dependent Ca²⁺ uptake rate at different free Ca²⁺ concentrations. …”

Characterization of human neural progenitor cell (hNPC) derived neurons during neuronal differentiation. by Xuan Yuan (225365)

“…There was decreased density of VGAT and synapse formation in the hNPC-derived neurons from <i>PIGA</i>c.1234C>T cells compared to the control cell line (<i>PIGA</i>wt) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0174074#pone.0174074.s003" target="_blank">S3 Fig</a>). …”

Validation of the primary screen hits with secondary luciferase-based invasion and red-green invasion assays. by Rajshekhar Y. Gaji (417441)

“…The values obtained with non-targeting siRNA controls were set at 100% invasion. A total of 81 genes (red asterisks) showed significant decrease (<i>p</i><0.05, one sample <i>t</i>-test) in parasite invasion compared to NTsiRNA controls. …”

Expression of MMP7 and TIMP1 in wounds. by Katharina Sommer (463202)

“…Septic animals show a significant decrease in MMP7 expression on day 2 and 6 compared to control mice. …”

Characterisation and influence of the content of waste foundry sand on rendering mortars by Juliana Machado Casali (4696111)

“…The results demonstrated that the waste foundry sand had an influence on the properties of the mortars in fresh state (mainly for the mortar with 100% waste foundry sand, which required the use of a larger amount of water to obtain the same consistence) and in the hardened state (decrease in strength, mass density and modulus of elasticity). …”

Ca²⁺ sparklets in DSM are affected by, but not dependent upon, signals from the SR. by Peter Sidaway (190696)

“…In the presence of the VGCC antagonist R-(+)-Bay K 8644 (1 μM) and CPA (10 μM), there was a significant decrease in the frequency (D) but not amplitude (E) of Ca²⁺ sparklets. …”

Glycosylation inhibitors block thrombin-induced sRBC adhesion to HUVECs. by Pushpankur Ghoshal (580530)

“…The level of sRBC adhesion to untreated HUVECs was set to 100%. **, p<0.0001 <b>B</b>. Glycosylation inhibitors decrease thrombin-induced sRBC adhesion to HUVECs. …”