Increased P-gp levels are associated with diminished drug uptake in drug-resistant MCF-7 cells. by Derek W. Edwardson (4439047)

“…Tritiated docetaxel (H3-TXT) was administered at a concentration of 2.5 nM, either with or without 100 nM Tariquidar for 12 hours and docetaxel uptake was determined by measuring the radioactivity of cells. …”

Overview of the comparative analysis of deconvolution model performances using synthetic spatial data in four different scenarios and six different mixture percentages. by Nuray Sogunmez Erdogan (21533872)

“…<b>B</b>, The mean standard deviations of RMSE scores. WISpR emerged as low error prone especially in blended data (Mix[50,50,0], Mix[50,40,10], Mix[50,30,20], Mix[50,20,30], Mix[50,10,40], Mix[50,0,50]). …”

The effects of β₁-adrenoceptor stimulation on I_Kur and I_Kto,f. by Vladimir E. Bondarenko (411443)

“…Simulation data is obtained with 200-ms pulses from a holding potential of −100 mV to +40 mV at stimulation frequency 0.02 Hz. …”

DataSheet_1_Efficacy and safety of herbal formulas with the function of gut microbiota regulation for gastric and colorectal cancer: A systematic review and meta-analysis.docx by Bowen Xu (5903801)

“…There were no significant differences in ORR [RR = 1.32, 95% CI (0.94~1.86)] and DCR [RR = 1.22, 95% CI (0.99~1.50)], but they can improve the KPS response rate [RR = 1.62, 95% CI (1.13, 2.32)] and decrease the incidence of myelosuppression, nausea and vomiting, diarrhea, and hepatic and renal dysfunction in CRC.…”

Comparison of choroidal thickness in normal eyes and different ocular pathologies in a Brazilian population by Murilo U. Polizelli (10371024)

“…Results: Seventy-four eyes from 74 patients with a mean age of 51.4 years were analyzed in the normal group with a mean nasal, subfoveal and temporal choroidal thickness measurements were 301.30 ± 12.86 μm, 311.61 ± 12.62 μm and 309.28 ± 12.28 μm respectively. …”

Mitochondrial superoxide governs cell number. by Tejas M. Gupte (743674)

“…(the depletion of mitofusin alone) to 5.4 x 10⁸ ± 0.7 x 10⁸. Values are mean ± SD from a three experiments with 50 cells per genotype.…”

Dependency of Cl⁻ accumulation on the site of synaptic input and KCC2 level. by Nicolas Doyon (344567)

“…Synaptic background activity was the same as in <b>B</b>. Mean IPSC was measured at a “test” synapse activated at 40 Hz for 200 ms every second over 50 s of simulated time. …”

GPI anchored proteins are required for neural differentiation. by Xuan Yuan (225365)

“…On day 4 (middle), single homogeneous hiPSC-EBs collected were pooled in a 10 cm plate (4X magnification, scale bar is 100μm). …”

Scale-Free Correlation. by Takayuki Niizato (162226)

“…We ran simulations 100 times for flocks with 100, 200, and 300 individuals, respectively, and averaged the results over a certain interval (100 L on the horizontal axis). …”

Effect of Ultra-fine Traditional Chinese Medicine Compounds on Regulation of Lipid Metabolism and Reduction in Egg Cholesterol of Laying Hens by Y Song (5161109)

“…These results suggest that the diet supplemented with TCM could increase the expression of apoA I and apoB100 mRNA in the liver, and decrease lipid content in the serum, and reduce egg cholesterol in layers.…”

Effect of broad-spectrum potassium channel blockers on evoked DA overflow. by Philippe Martel (350692)

“…(E) After a 30 min application of 100 µM 4-AP, 1 µM ConoTX was applied and caused a ∼ 90% decrease in evoked DA release. …”

Cosmosiin and angolensin inhibit PC3 cell motility and migration. by Emily Powell (185352)

“…(B) Transwell migration assays measured the ability of cosmosiin (B) and angolensin (C) to inhibit cellular migration of PC3 cells toward a chemoattractant. Cosmosiin (B) and angolensin (C) decreased the ability of PC3 cells to migrate through the pore, and this decreased ability was ablated by the antagonist ICI 182,780 at 100 nM.…”

Differential effects of BSA and lysozyme molecular crowding agents in CaMKII to GluN2B binding. by Dayton J. Goodell (559732)

“…<p><i>A</i>, CaMKIIα (40 nM subunits) binding to GST-GluN2B-C that was immuno-immobilized on anti-GST coated microtiter wells was induced by Ca²⁺/CaM (1 mM/1 µM) in the presence of ADP (100 µM) for 15 min at room temperature. …”

POm shows pronounced response disparity to active and passive whisker stimuli. by Anton Sumser (21021061)

“…Top: heatmaps of individual neuron PSTHs, normalized to baseline before puff and ordered by peak response latency. Bottom: mean population PSTHs, mean whisker angles (orange lines), and mean whisking amplitude over the plotted time range (−25 to 75 ms, orange bars) from recordings shown in the top panel. …”

Table_1_Effectiveness of a protein-supplemented very-low-calorie diet program for weight loss: a randomized controlled trial in South Korea.docx by Eunbyul Cho (12135697)

“…Waist circumference (−8.35 cm vs. -4.85 cm; mean difference, −3.49 cm; 95% CI, −6.48 to −0.50) and visceral fat area (−28.28 cm² vs. −13.26 cm²; mean difference, −15.03cm²; 95% CI, −29.01 to −1.04) also significantly decreased in the PSVLCD group at 12 months.…”

Colocalized synaptophysin-GFP puncta. by Irina Antonova (369433)

“…An increase in N1 (for example, comparing glutamate to control) corresponds to a rapid increase in sites at 10 min, an increase in P3 corresponds to a gradual increase (or a smaller decrease) from 10 min to 3 hrs, and an increase in N2 corresponds to an increase in stable sites.…”

Estrogen dose-dependent depletion of oocytes. by Clémentine Chalmey (5657233)

“…Higher magnification of TRA98 labeling shows oocyte-specific expression (C). Scale bar = 100 µm. D–E. Stereological estimation of ovarian volume (D) and oocyte numbers per ovary (E) at PND3 in controls, and as a function of E2 dose, show a dose-dependent decrease of both parameters. …”

The power for detecting association with secondary traits in selected samples. by Dajiang J. Liu (120143)

“…Power was evaluated using 10,000 replicates for a significance level of . For each replicate, 5,000 individuals with extreme quantitative traits were selected from a cohort of 100,000 individuals.…”

Effect of apigenin intake on IκBα levels in the dorsolateral prostate of TRAMP mice. by Sanjeev Shukla (106046)

“…A significant increase in total IκBα and a marked decrease in p-IκBα levels is observed after apigenin intake. …”

NC score, sCr, normalized fold TIMP-2 expression and staining of urinary sediment of representative patient #1. by Daniela Knafl (4234138)

“…Improvement of renal function was accompanied by an increase of urinary sediment TIMP-2 expression, and decrease in NC score parameter. 100 days after kidney transplantation the patient was alive with a serum creatinine of 2.1 mg/dL. …”