The expression of <i>Zif268</i> is decreased in the dentate gyrus of HIWM trained rats as compared to RM or LIWM rats. by Mickaël Antoine Joseph (821433)

Improvement of the eye morphology and the motor performance phenotypes of FRDA flies by decreased expression of genes implicated in zinc and copper homeostasis. by Sirena Soriano (348274)

Inhibition of MMP2 decreases apoptosis and attenuates insulin secretion dysfunction caused by oxidative stress in INS-1 cells. by Chongxiao Liu (644813)

Selection for rare alleles that increase the rate of (a) monandry or (b) selfing. by Michael Francis Scott (5447600)

IMB5043 arrests G₂/M phase and decreases the motility and invasion of SMMC-7721 cells. by Jianhua Gong (530290)

“…<p>(A). Cell cycle distribution was determined by flow cytometry after PI staining. …”

Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba <i>L.</i> (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism i... by Caina Li (4126462)

“…SZ-A also significantly lowered the expression of aldo-keto reductase 1b7 and its upstream gene farnesoid X receptor (FXR) and increased the expression of cholesterol 7α-hydroxylase and small heterodimer partner. …”

Fig 1 - by Pedro A. R. Vanzele (17655589)

S1 Fig - by Pedro A. R. Vanzele (17655589)

Fig 4 - by Pedro A. R. Vanzele (17655589)

Numbers of supporting cells are unaffected in morphants, while numbers of hair cells decrease in morphants. by Fei Liu (21082)

siRNA-based knockdown of <i>CLU</i> results in decreased VWF and CLU protein expression but no change in <i>VWF</i> mRNA content. by Allaura A. Cox (17980027)

Targeting of Vps34 reduces B16F10 tumor growth and working model for Vps34-dependent regulation of eTreg transitional heterogeneity and maintenance. by Erienne G. Norton (9612079)

Experimental design depicting ampicillin treatment of <i>B</i>. <i>germanica</i>. by Seogwon Lee (11747633)

Image_1_TMEM16A Inhibition Preserves Blood–Brain Barrier Integrity After Ischemic Stroke.TIF by Pin-yi Liu (7136123)

“…Furthermore, our mechanistic study showed that TMEM16A knockdown alleviated NF-κB activation and nuclear translocation, indicating that TMEM16A knockdown downregulated OGD/R-induced ICAM-1 expression in an NF-κB-dependent manner. …”

Image_2_TMEM16A Inhibition Preserves Blood–Brain Barrier Integrity After Ischemic Stroke.TIF by Pin-yi Liu (7136123)

“…Furthermore, our mechanistic study showed that TMEM16A knockdown alleviated NF-κB activation and nuclear translocation, indicating that TMEM16A knockdown downregulated OGD/R-induced ICAM-1 expression in an NF-κB-dependent manner. …”

Mean ranks for comparison of a) MNCSE and b) MSE at temporal scales 1 to 15 for quantifying the dynamics of pathological with disease severity. by Imtiaz Awan (5233526)

Mean ranks for comparison of a) MNCSE and b) MSE at temporal scales 1 to 15 for quantifying the dynamics of pathological with disease severity. by Imtiaz Awan (5233526)

Mean ± SD values of the (a) MSE and (b) MNCSE computed from40 different WGN and 1/f noise signals. by Imtiaz Awan (5233526)

Mean percentage changes (95% CI) in total testosterone, SHBG and free testosterone (mITT analysis). by Chanel Avenant (409756)

TPX2 selectively regulates the levels of H4K16ac during G1-phase. by Gernot Neumayer (77179)

“…<p>(A) Depletion of TPX2 by siRNA in MCF7 cells causes a constitutive decrease in H4K16ac levels that correlates with the known increase in ionizing radiation-dependent (10 Gy) γ-H2AX levels <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0110994#pone.0110994-Neumayer2" target="_blank">[15]</a>. …”