Bifunctional effects of O-methylated flavones from <i>Scutellaria baicalensis</i> Georgi on melanocytes: Inhibition of melanin production and intracellular melanosome transport by Michiko Kudo (3737575)

“…<i>baicalensis</i> are baicalin, wogonoside, baicalein, wogonin, and oroxylin A. Among these five flavones, wogonin and wogonoside consistently inhibited melanogenesis in both B16F10 melanoma cells and primary melanocytes. …”

Regulation of neural differentiation at least partly via <i>PEX11B-SIRT1-PPARɣ</i> axis. by Maryam Esmaeili (6457958)

Effects of ADMA on formaldehyde-induced inhibition of CBS expression as well as decrease in H₂S generation in PC12 cells. by Xiao-Qing Tang (287111)

Most miRNAs in Ago1 RISC are stable with age whereas transposon siRNAs in Ago2 RISC decrease with age. by Siobhan Gartland (14129274)

Table_2_Decrease of Clone Diversity in IgM Repertoires of HBV Chronically Infected Individuals With High Level of Viral Replication.pdf by Binbin Hong (9989819)

Table_4_Decrease of Clone Diversity in IgM Repertoires of HBV Chronically Infected Individuals With High Level of Viral Replication.pdf by Binbin Hong (9989819)

Table_3_Decrease of Clone Diversity in IgM Repertoires of HBV Chronically Infected Individuals With High Level of Viral Replication.pdf by Binbin Hong (9989819)

Presentation_1_Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.pdf by Lisa J. M. Slimmen (16464600)

“…Compared to matched blood monocytes, AMs had a higher expression of CD16, CD91, and PD-1, and a lower expression of CD163, SIRPα and CD36.…”

Dietary n-3 Polyunsaturated Fatty Acids (PUFA) Decrease Obesity-Associated Th17 Cell-Mediated Inflammation during Colitis by Jennifer M. Monk (118336)

<i>brca2</i> Mutations Dramatically Decrease HR-h Repair, Increase SSA Repair, and Result in Increased Deletion Formation by Martha Klovstad (86324)

Data Sheet 1_The “best practices for farming” successfully contributed to decrease the antibiotic resistance gene abundances within dairy farms.docx by Barbara Salerno (12894908)

“…ARGs (bla_TEM, ermB, sul2, and tetA) were initially screened by end-point PCR, followed by quantification using digital droplet PCR. …”

GFP::DAF-16 and DAF-16AM::GFP have similar expression levels. by İçten Meraş (13184380)

Alignment between <i>C</i>. <i>elegans</i> glucose-6-Phosphate translocase ortholog and human, mouse, zebrafish, and fly glucose-6-Phosphate exchanger. by Brian Onken (86790)

Lifespan data. by Brian Onken (86790)

Increased Locomotory Healthspan and Survival with <i>pck-2</i> Overexpression, as Well as Expression of <i>pck-2</i> in the Intestine, Require <i>daf-16</i>. by Brian Onken (86790)

Excess glucose availability negatively impacts healthspan of young and old animals; conversely, the benefits of disrupting glycolysis do not include extended maximal lifespan. by Brian Onken (86790)

Disrupting Glycolysis-promoting Genes Extends <i>C</i>. <i>elegans</i> Healthspan, Whereas High Glucose and Gluconeogenic Gene Disruptions Shorten Healthspan. by Brian Onken (86790)

“…Trials with 5 and 13 day old animals also showed impaired older age locomotion in 4% glucose (Supplemental <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.s002" target="_blank">S1A and S1B Fig</a>). …”

Gluconeogenic gene <i>fbp-1</i> expression is required for healthspan extension under dietary restriction. by Brian Onken (86790)

Dietary Restriction Induces Gluconeogenic Gene <i>pck-2</i> Expression via DAF-16, and <i>pck-2</i> Expression is Needed for DR-associated Healthspan Benefits. by Brian Onken (86790)

“…Elevated gluconeogenic activity (dependent on DAF-16-promoted PCK-2 expression) acts in a feed-forward capacity to further enhance the gluoconeogenic pathway and may inhibit glycolysis/insulin signaling to promote/maintain DAF-16 signaling and healthy metabolism (inhibition represented by a dashed line).…”

The healthspan effects of glycolytic and gluconeogenic disruptions are absent in the <i>age-1</i> insulin signaling mutant background. by Brian Onken (86790)