Sensitivity of simulated pathogen diversity to host lifespan and environmental transmission. by Benjamin Roche (84064)

“…The <i>z</i>-axis corresponds to the mean antigenic diversity over the 40-y period. A decrease in environmental uptake rate (<i>x</i>-axis) dramatically reduces mean antigenic diversity (average of the number of strains) and switches the phylogenetic pattern from one that depicts broad coexistence to an immune escape profile. …”

Cx45 distribution in CA3 after epileptiform activity. by Erika R. Kinjo (642091)

“…(B, C) Quantification of mean pixel intensity (n = 4 animals per group) showed significant increase in (F) SO and decrease in (I) SLM in the latent period, compared with control animals (D, G). …”

ΔΨ_m loss and derived dataset. by Yara Reis (187851)

“…<p><b>A</b>) Standard deviation (StDev) of TMRM signal as a heatmap- mean values of StDev were translated into a heatmap (color scaled from 0 to 50 in arbitrary units, a.u.). …”

Solubilized P and biomass produced by <i>Aspergillus niger</i> FS1 mutants compared to the wild type. by Ubiana de Cássia Silva (643658)

“…P (%) = (mMUT–mWT)/mWT×100; mMUT: mean solubilized P for the mutant; mWT: mean solubilized P for the wild type. …”

ANX2/p11 interaction mediates binding of ALL cells to osteoblasts. by Anilkumar Gopalakrishnapillai (812984)

“…Error bars denote SD of the Mean from three independent experiments. Asterisk indicates statistical significance, P < 0.01. …”

Antihypertensive effect and the underlying mechanisms of action of phytolaccagenin in rat models by Imran Ul Haq (12676309)

“…</p> <p>Intravenous administration of phytolaccagenin decreased mean arterial pressure (MAP), significantly, in normotensive and hypertensive anesthetized rats. …”

Knockouts of <i>gpr-3</i> lack cAMP signaling response to melatonin. by Cathryn S. D. Maienza (20629929)

“…<p>Difference in relative cAMP concentration between <i>gpr-3</i>^<i>+</i> (N380-1, n = 6), <i>gpr-3</i>^{<i>-</i> (}N380-2, n = 6), and <i>gna-1</i>^<i>-</i>(n = 6) strains after 10-minute treatment with 5ng/mL melatonin in sterile water. Untreated group was treated only with water. …”

Celastrol has an inhibitory effect on TNFα-induced NF-κB signaling in MDA-MB-231 cells. by Laura Mezzanotte (223692)

“…<p>(3.A) Graph representing the decrease in fold NF-κB induction in MDA-MB-231 cells using celastrol by the multicolor assay (* p value <0.05; ** p value <0.01). (3.B) Composite image of the unmixed spectrum of luciferases: green signals represent CBG99 emission, red signals represent PpyRE9 emission spectrum and blue signals represent ExtGluc expression in control cells (first column) and cells treated with TNFα in combination with increasing concentrations of celastrol (0.1–3 µM). (3.C) Left: graph reporting the relative band intensity of p65 protein from the nuclear extract of control sample and samples treated with TNFα (10 ng/ml) or TNFα + celastrol (0.1 µM; 0.5 µM and 1 µM). …”

Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition - Fig 9 by Himakarnika Alluri (2735689)

“…Animals were divided into sham (n = 6), vehicle + sham (n = 6), vehicle + TBI (n = 5) and melatonin + TBI (n = 6). Data are expressed as ng/brain cortex ± SEM. ‘*’ indicates statistical significance. …”

TGF-β₁ dependent effects on AP activity by SB431542 are depending on time. by Sabrina Ehnert (359631)

“…<p>Primary human osteoblasts stimulated with 5 ng/ml hra TGF-β₁ in the presence or absence of 20 nM SB431542. …”

Phenotypes of ovary cultures treated with FST288. by Zhengpin Wang (147664)

“…<p>Ovaries at 17.5 dpc were cultured for 7 days without treatment (as a control) or with 500 ng/mL FST288. …”

Supplementary Material for: Diagnostic value of sST2, VCAM-1 and adiponectin in patients with breast cancer to predict anti-tumor treatment-related cardiac events: A pilot study by Rosenkaimer S.L. (12968150)

Data_Sheet_1_Coastal Flooding in the Balearic Islands During the Twenty-First Century Caused by Sea-Level Rise and Extreme Events.zip by Pau Luque (11248140)

“…Some beaches will lose more than 50% of their surface by the end of the century: 20–50% of them under RCP4.5 scenario and 25–60% under RCP8.5 one. …”

Renal lipids and inflammatory changes in kidney of HPRT^-/- treated mice. by Cristina Zennaro (424123)

“…The WT tissue is completely negative, whereas kidneys from HPRT^-/- mice show numerous positive areas in the interstitium, mainly within and around the lumen of dilated tubules. Scale bars = 50 μm. (b) Gene expression analysis of adipogenesis-related molecules C-EBP alpha and beta and PPAR alpha and gamma shows no differences based on the genotype in vehicle-treated mice, whereas a significant increase of C-EBP alpha and beta and a significant decrease of PPAR alpha are detected in allopurinol-treated HPRT^-/- animals. …”

HMGB1 induces Src activation. by Mengchen Zou (725646)

“…Representative immunoblots showing that PP2 (C) and CGP77675 (D) decreased HMGB1-induced Src phosphorylation. Cells were preincubated with 1, 2.5, 5, or 10μM PP2 or 0.5, 1, 2.5 or 10 μM CGP77675 for 1 h, respectively. 200 ng/ml HMGB1 was then added and cells were incubated for an additional 24h. …”

Data_Sheet_1_Variability of Myocardial Strain During Isometric Exercise in Subjects With and Without Heart Failure.pdf by Moritz Blum (9043115)

“…In controls, LV GLS remained stable in 36.8%, increased in 36.8% and decreased in 26.3% of subjects during HG. In HF subgroups, similar patterns of LV GLS response were observed (HFpEF: stable 41.2%, increase 35.3%, decrease: 23.5%; HFmrEF: stable 50.0%, increase 16.7%, decrease: 33.3%; HFrEF: stable 33.3%, increase 22.2%, decrease: 44.4%, p = 0.668). …”

PG increased the number of necrotic cells in HepJ5 cells. by Po-Li Wei (292225)

“…(D) The number of late apoptotic cells was increased after exposure to 50 μM PG in HepJ5 cells. The data are presented as the mean±SD of three independent experiments in triplicate.…”

Perinatal nicotine exposure produces attention deficits in male offspring in the object based attention (OBA) test. by Lin Zhang (8926)

“…*<i>p</i><0.05. [Mean ± SEM: Male: W: 73.95 ±4.65; S: 74.93 ± 4.85; N + S: 50.04 ± 4.65; Female: W: 56.01 ± 4.60; S: 62.61 ± 4.80; N + S: 59.46 ± 7.85].…”

Operant self-stimulation of nigral dopamine neurons. by Mark A. Rossi (348414)

“…Values are mean ± s.e.m.</p>…”

Sodium tungstate treatment significantly modulates expression of proteins involved in neuronal plasticity. by Marta Amigó-Correig (153831)

“…**<i>p</i><0.01; ***<i>p</i><0.001. Data are the mean±SD.</p>…”