Data_Sheet_1_Lack of the Transient Receptor Potential Vanilloid 1 Shifts Cannabinoid-Dependent Excitatory Synaptic Plasticity in the Dentate Gyrus of the Mouse Brain Hippocampus.PD... by Jon Egaña-Huguet (11089344)

“…These functional changes were associated with an increase in the maximum binding efficacy of guanosine-5′-O-(3-[³⁵S]thiotriphosphate) ([³⁵S]GTPγS) stimulated by the CB₁ receptor agonist CP 55,940, and a significant decrease in receptor basal activation in the TRPV1-/- hippocampus. …”

Table_1_Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin.docx by Jinbin Yuan (2451628)

“…DAS 3.1 software suggests the pharmacokinetic profiles of the five components in rats be depicted as a two-compartment pharmacokinetic model. …”

Image_1_Xiaochaihutang Improves the Cortical Astrocyte Edema in Thioacetamide-Induced Rat Acute Hepatic Encephalopathy by Activating NRF2 Pathway.tif by Weiyi Jia (8719173)

“…Astrocytes treated with 5 mM ammonia also showed an increase in the AQP4 protein expression but a decrease in XCHT compound serum and ammonia-induced cell edema groups. …”

DataSheet1_Antisense targeting of FOXP3+ Tregs to boost anti-tumor immunity.docx by Tatiana Akimova (345316)

“…In murine studies, we observed a significant inhibition of tumor growth, while 13.6% (MC38) to 22% (TC1) of tumors were completely resorbed, in conjunction with ~50% decrease of Foxp3 mRNA by qPCR and decreased numbers of intratumoral Tregs. …”

Table_4_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy... by Pei He (836326)

“…The multivariable logistic regression model showed that the decrease in CCR was associated with a higher risk of osteoporosis/fracture in all models (all P<0.05). …”

Image_2_Xiaochaihutang Improves the Cortical Astrocyte Edema in Thioacetamide-Induced Rat Acute Hepatic Encephalopathy by Activating NRF2 Pathway.tif by Weiyi Jia (8719173)

“…Astrocytes treated with 5 mM ammonia also showed an increase in the AQP4 protein expression but a decrease in XCHT compound serum and ammonia-induced cell edema groups. …”

Table_1_Spatiotemporal Change of Net Primary Productivity and Its Response to Climate Change in Temperate Grasslands of China.XLS by Rong Ma (500564)

“…The annual NPP showed increasing trends for all the different grassland vegetation types, with the smallest increase for temperate desert steppe (2.2 gC/m²/year) and the largest increase for temperate meadow (5.4 gC/m²/year). The correlation results showed that increased annual precipitation had a positive relationship with the NPP of temperate grasslands. …”

The effects of FRLFE on the NF-κB-dependent transcription of the <i>iNOS</i> gene. by Ryota Yamanishi (547533)

“…<p>(<b>A</b>) FRLFE decreases the iNOS promoter activity. …”

Data_Sheet_1_Exploring Peritumoral Neural Tracts by Using Neurite Orientation Dispersion and Density Imaging.docx by Shin Tai Chong (11483152)

“…The regions with edematous CST in NODDI-derived tractography demonstrated a significant decrease in the intracellular volume fraction (VF_ic, p < 0.000) and an increase in the isotropic volume fraction (VF_iso, p < 0.014). …”

Responses of Nucleus Tractus Solitarius (NTS) early and late neurons to blood pressure changes in anesthetized F344 rats by Jenya Kolpakova (3909658)

“…Our findings were that: 1) Thirty-five neurons (from 46 neurons) increased firing, whereas others neurons either decreased firing upon AP elevation, or were biphasic: first decreased firing upon AP elevation and then increased firing during AP decrease. 2) Fourteen neurons with excitatory responses were activated and rapidly increased their firing during the early phase of AP increase (early neurons); whereas 21 neurons did not increase firing until the mean arterial pressure changes (ΔMAP) reached near/after the peak (late neurons). 3) The early neurons had a significantly higher firing rate than late neurons during AP elevation at a similar rate. 4) Early neuron NA-ΔMAP relationship could be well fitted and characterized by the sigmoid logistic function with the maximal gain of 29.3. 5) The increase of early NA correlated linearly with the initial heart rate (HR) reduction. 6) The late neurons did not contribute to the initial HR reduction. …”

Data_Sheet_1_Open-Ocean Minima in δ13C Values of Particulate Organic Carbon in the Lower Euphotic Zone.docx by Hilary G. Close (9079080)

“…In 51 vertical profiles, δ¹³C_POC values in the lower euphotic zone on average are 1.4‰ lower than δ¹³C_POC values in the upper euphotic zone of open ocean settings. In a majority of locations this vertical decrease in δ¹³C_POC values is >2‰ and up to 5‰, larger than the commonly recognized vertical δ¹³C variation in dissolved inorganic carbon over the same depths. …”

Image_6_Profiling the Urinary Microbiota in Male Patients With Bladder Cancer in China.PDF by Peng Wu (210686)

“…We observed increased bacterial richness (Observed Species, Chao 1 and Ace indexes; cancer vs. control; 120.0 vs. 56.0; 134.5 vs. 68.3; and 139.6 vs. 72.9, respectively), enrichment of some bacterial genera (e.g., Acinetobacter, Anaerococcus, and Sphingobacterium) and decrease of some bacterial genera (e.g., Serratia, Proteus, and Roseomonas) in cancer group when compared to non-cancer group. …”

Table_6_Profiling the Urinary Microbiota in Male Patients With Bladder Cancer in China.DOCX by Peng Wu (210686)

“…We observed increased bacterial richness (Observed Species, Chao 1 and Ace indexes; cancer vs. control; 120.0 vs. 56.0; 134.5 vs. 68.3; and 139.6 vs. 72.9, respectively), enrichment of some bacterial genera (e.g., Acinetobacter, Anaerococcus, and Sphingobacterium) and decrease of some bacterial genera (e.g., Serratia, Proteus, and Roseomonas) in cancer group when compared to non-cancer group. …”

Table_2_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy... by Pei He (836326)

“…The multivariable logistic regression model showed that the decrease in CCR was associated with a higher risk of osteoporosis/fracture in all models (all P<0.05). …”

Image_2_Profiling the Urinary Microbiota in Male Patients With Bladder Cancer in China.TIF by Peng Wu (210686)

“…We observed increased bacterial richness (Observed Species, Chao 1 and Ace indexes; cancer vs. control; 120.0 vs. 56.0; 134.5 vs. 68.3; and 139.6 vs. 72.9, respectively), enrichment of some bacterial genera (e.g., Acinetobacter, Anaerococcus, and Sphingobacterium) and decrease of some bacterial genera (e.g., Serratia, Proteus, and Roseomonas) in cancer group when compared to non-cancer group. …”

Image_2_Spatiotemporal Change of Net Primary Productivity and Its Response to Climate Change in Temperate Grasslands of China.TIF by Rong Ma (500564)

“…The annual NPP showed increasing trends for all the different grassland vegetation types, with the smallest increase for temperate desert steppe (2.2 gC/m²/year) and the largest increase for temperate meadow (5.4 gC/m²/year). The correlation results showed that increased annual precipitation had a positive relationship with the NPP of temperate grasslands. …”

Image_1_The Systemic Administration of the Histamine H1 Receptor Antagonist/Inverse Agonist Chlorpheniramine to Pregnant Rats Impairs the Development of Nigro-Striatal Dopaminergic... by Berenice Márquez-Valadez (6590576)

“…These results indicate that H₁R blockade at E14–E16 favors the differentiation of dopaminergic neurons, but hampers their migration, leading to a decrease in dopaminergic innervation of the striatum in post-natal life.…”

DataSheet_1_Analyzing the impacts of cadmium alone and in co-existence with polypropylene microplastics on wheat growth.docx by Zhiwei Han (9987860)

“…For example, on third day, the DW of the Cd treatment group increased by 6.9% compared to CK, whereas the DW of the 100 µm PP-MPs+Cd treatment group decreased by 8.4% compared to CK. The co-occurrence of Cd and PP-MPs indicated that 50 μm PP-MPs+Cd had an antagonistic impact on wheat seedling growth, whereas 100 μm PP-MPs+Cd had a synergistic impact due to the larger size of PP-MPs. …”

SR Ca²⁺ uptake, Ca²⁺ signaling proteins, and transcriptional factors. by Mei Hua Gao (458915)

“…<b>Lower:</b> Expression of AC6mut decreased SERCA2a affinity for Ca²⁺. The effective concentration of Ca²⁺ for 50% maximal effect (EC₅₀) was calculated from the initial ATP-dependent Ca²⁺ uptake rate at different free Ca²⁺ concentrations. …”

Maize fertigation with treated sanitary wastewater: growth and yield by Pablo Fernando Santos Alves (5788457)

“…<p></p><p>ABSTRACT We evaluated the growth and yield of maize field, fertigated with different wastewater rates coming from Janaúba sewage treatment plant (Minas Gerais State, Brazil). The split-plot on a randomized complete block design was used with five levels: mineral fertilizer + clean water, treated wastewater like to 50%, 100%, 150% and 200% fertilization with 60 kg.ha-1 K2O topdressing. …”