Glutamate accelerates synaptic release from cone terminals. by Skyler L. Jackman (222281)

“…(C) Time-course of FM1-43 fluorescence decreases from cone terminals in darkness (<i>n</i> = 27, error bars are obscured by the data points) and 2 mM glutamate (<i>n</i> = 5). …”

Detection of cerebral hemodynamic changes using CBF maps. by Taeyun Ku (124442)

“…<p>(A) Representative T_rising maps for mice anesthetized with either 1.5% isoflurane or 0.1 mg/g ketamine and 0.01 mg/g xylazine. …”

Subsampling slows down parametric inference. by Quentin J. M. Huys (223756)

“…The coloured traces inference with show sampling timesteps of Δ<i>_s</i> = {0.01,0.02,0.05,0.1,0.5} ms respectively. All particles were run with a Δ = 0.01 ms timestep, and the total recording was always 10 ms long, meaning that progressive subsampling decreased the total number of data points. …”

Nrf1 is negatively regulated by its CTD. by Yiguo Zhang (512679)

“…FITC-labelled second antibody was used to locate V5-tagged proteins. Nuclear DNA was stained by DAPI. …”

An evaluation of front seat distance from rear facing child restraint systems in prevention of injury in frontal crash tests by Matthew R. Maltese (7217915)

“…On average, the −20, 0, or 15 mm distances yielded a 60% reduction in head injury criterion with 15 millisecond window (HIC15), and a 60% to 80% reduction in neck tension, compared to the 70 and 140 mm distances; chest acceleration also decreased for the convertible seat only. In the case of both carriers and convertibles, each mm of distance the CRS moves away from the front seatback up to 70 mm, adds 5.3 HIC15 points (95% Credible Interval (CrI):[4.6, 6.2]), and 3.5 Newtons (95% CrI: [2.2, 4.8]) of neck tension, on average.…”

DPP6 regulates a channel with properties similar to TASK-3. by Brian M. Nadin (401054)

“…As expected expression of high levels of TASK-3 dramatically increases membrane resting conductance, much of which is sensitive to block by external pH 6.0. Scale bar: 20 mV, 50 ms. <b>C)</b> Summary results testing sensitivity of the resting conductance to external pH 6.0 (WT (n = 11), mDPP6 RNAi (n = 5), rDPP6 Rescue (n = 8), TASK-3 (n = 6)), 500 µM external Zn²⁺ (WT (n = 6), mDPP6 RNAi (n = 5), rDPP6 Rescue (n = 6), TASK-3 (n = 6)) and suppression by 10 µM muscarine (WT (n = 8), mDPP6 RNAi (n = 5), rDPP6 Rescue (n = 4), TASK-3 (n = 6)). …”

Vibrotactile discrimination task. by Jaldert O. Rombouts (2217433)

“…Left panel shows the response for F1 = 20Hz and F2 = F1±5Hz (solid +5Hz, dashed -5Hz). The response of the <i>Q</i>-value units is coded following the color scheme in panels A and B. …”

Select hematology from marmosets, some treated, then exposed to intranasally to low dose monkeypox virus. by Eric M. Mucker (146111)

“…White blood cells (WBC) (A), lymphocytes (B), monocytes (C) and granulocytes (D) were elevated, and platelets (PLT) (E) decreased in most of the control animals whereas treated animals did not vary much from earlier time points. …”

Timing of glucocorticoid administration determines severity of lipid metabolism and behavioral effects in rats by Tao Wu (16763)

“…In addition, serum levels of corticosterone, 5-hydroxy tryptamine and norepinephrine were decreased in the Dex0 group but not in the Dex12 group compared to the control group. …”

Image_4_Systemic Inflammation Increases the Susceptibility to Levodopa-Induced Dyskinesia in 6-OHDA Lesioned Rats by Targeting the NR2B-Medicated PKC/MEK/ERK Pathway.JPEG by Aijuan Yan (4578646)

“…</p><p>Methods: To evaluate the possible influence of systemic inflammation in the appearance of LID, the PD rats received an intraperitoneal (IP) injection of various concentrations of lipopolysaccharides (LPS, 1, 2, and 5 mg/kg) or saline. One day later, these PD rats started to receive daily treatment with L-dopa (6 mg/kg) along with benserazide (6 mg/kg) or saline for 21 days, and dyskinesia was evaluated at several time points. …”

Image_1_Systemic Inflammation Increases the Susceptibility to Levodopa-Induced Dyskinesia in 6-OHDA Lesioned Rats by Targeting the NR2B-Medicated PKC/MEK/ERK Pathway.JPEG by Aijuan Yan (4578646)

“…</p><p>Methods: To evaluate the possible influence of systemic inflammation in the appearance of LID, the PD rats received an intraperitoneal (IP) injection of various concentrations of lipopolysaccharides (LPS, 1, 2, and 5 mg/kg) or saline. One day later, these PD rats started to receive daily treatment with L-dopa (6 mg/kg) along with benserazide (6 mg/kg) or saline for 21 days, and dyskinesia was evaluated at several time points. …”

Image_2_Systemic Inflammation Increases the Susceptibility to Levodopa-Induced Dyskinesia in 6-OHDA Lesioned Rats by Targeting the NR2B-Medicated PKC/MEK/ERK Pathway.JPEG by Aijuan Yan (4578646)

“…</p><p>Methods: To evaluate the possible influence of systemic inflammation in the appearance of LID, the PD rats received an intraperitoneal (IP) injection of various concentrations of lipopolysaccharides (LPS, 1, 2, and 5 mg/kg) or saline. One day later, these PD rats started to receive daily treatment with L-dopa (6 mg/kg) along with benserazide (6 mg/kg) or saline for 21 days, and dyskinesia was evaluated at several time points. …”

Dibucaine lessens dendritic beading induced by spontaneous spreading depolarizations (SDs) in penumbra. by W. Christopher Risher (213699)

“…<b><i>C</i></b>, Summary showing significantly decreased occurrence of dendritic beading (*<i>p</i><0.05; Chi-Square Test) when dibucaine is administered i.v. immediately following onset of the initial spreading depolarization. …”

Image_3_Systemic Inflammation Increases the Susceptibility to Levodopa-Induced Dyskinesia in 6-OHDA Lesioned Rats by Targeting the NR2B-Medicated PKC/MEK/ERK Pathway.JPEG by Aijuan Yan (4578646)

“…</p><p>Methods: To evaluate the possible influence of systemic inflammation in the appearance of LID, the PD rats received an intraperitoneal (IP) injection of various concentrations of lipopolysaccharides (LPS, 1, 2, and 5 mg/kg) or saline. One day later, these PD rats started to receive daily treatment with L-dopa (6 mg/kg) along with benserazide (6 mg/kg) or saline for 21 days, and dyskinesia was evaluated at several time points. …”

Image_4_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.tif by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_10_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.tif by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_6_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_4_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_9_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.png by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_3_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.PNG by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”