TNFα stabilizes myocardin mRNA through MEK/MAPK and NF-κB pathways. by Pavneet Singh (657177)

“…<p>(<b>A</b>) VSMCs were serum-starved for 24 h and transcription was blocked using α-amanitin (50 µM). …”

Data Sheet 1_Association of dietary index for gut microbiota and cardiovascular diseases in American adults: evidence from National Health and Nutrition Examination Survey 1999–201... by Hong Luo (205745)

“…Mediation analysis examined the role of body mass index (BMI).</p>Results<p>A total of 39,181 participants (mean age: 47.15 years) were included, with 49.18% female and 50.82% male. …”

Thermal-dependent product specificity over time. by Gabriel Piedrafita (155328)

“…<p>A total of 800 μM 6PG was incubated at different temperatures in 50 mM phosphate solution pH 5 containing 75 μM cysteine and 75 μM FeCl₂, and the formation of different sugar phosphate products was monitored over time. …”

Effects of Individual Micronutrients on CACO-2 Tight Junctional Proteins. by Mary Carmen Valenzano (484242)

“…This same procedure was used for quercetin (400μM), butyrate (5.0mM), berberine (100μM), and indole (1.0mM) at the concentrations that provided maximal barrier enhancement and for the same time periods used in Figs <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0133926#pone.0133926.g001" target="_blank">1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0133926#pone.0133926.g002" target="_blank">2</a>. …”

BTK Expression Levels Control DNA Binding Activity and Transcription Factor Function of Ikaros. by Hong Ma (48973)

“…Each siRNA was used at a 50 nM concentration. BTK siRNA (but not Ku80 siRNA) resulted in depletion of BTK protein without a decrease in the amount of IK protein. …”

Acute exposure to dopaminergic neurotoxicants attenuates the propagation of intercellular Ca²⁺ waves in primary astrocytes. by Karin M. Streifel (653838)

“…Quantitative analysis of Ca²⁺ wave propagation indicates that 100 µM MPP+ and 6-OHDA decreases the distance traveled in striatal astrocytes by>50% relative to control, whereas 100 µM DOPAC does not abolish wave distance like MPP+ and 6-OHDA although significantly decreased from control. n = 3 waves analyzed per group for each experiment over 3–4 independent experiments in separate cultures of striatal astrocytes; *<i>p</i><0.05 relative to control, ** <i>p</i><0.01 relative to control and treated groups.…”

Collateral effects are pervasive and vary across parallel evolution experiments in <i>E</i>. <i>faecalis</i>. by Jeff Maltas (1598305)

“…Although the color scale ranges from a 4× decrease to a 4× increase in IC₅₀, it should be noted that both resistance to the selecting drug (diagonal blocks) and collateral effects can be significantly higher. …”

The airway intrinsic BX-C code determines the outcome of <i>hh</i> signaling. by Ryo Matsuda (685668)

“…Note that Salm expression in DT shows a posterior-to-anterior decrease. Upon overexpression of <i>Ubx</i> (G), <i>abdA</i> (H) or <i>AbdB</i> (I), DTa1 becomes negative for Kni and positive for Salm (asterisks). …”

Post-meal glycemic curve of T2DM patients without or with raw cinnamon. by Fernanda Duarte Moreira (19825891)

“…The line at the value of 63 mg/dL (3.5 mmol/L) indicates the maximum mean blood glucose rise achieved by healthy individuals after ingesting 50 g of carbohydrate from 27 tested foods [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0311501#pone.0311501.ref194" target="_blank">194</a>]. …”

Complementary conditioning measures in healthy subjects. by Gabriela Ribeiro (4748373)

“…<b>(G) Hunger</b> ratings remained stable from pre- to post-conditioning (t₍₅₀₎ = 0.3, <i>P</i> = 0.8) as well as <b>(H) Thirst</b> ratings (t₍₅₀₎ = 0.5, <i>P</i> = 0.6; paired <i>t</i> test). …”

Data_Sheet_4_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Unequal Impact of COVID-19 on Private and Academic Neurosurgical Workforce: Results of an International Survey.PDF by Sami Ridwan (11510080)

“…</p><p>Conclusion: The lockdown imposed in many countries by the COVID-19 outbreak called for immediate modification of working routine and resulted in a dramatic decrease of elective surgical procedures. …”

Data_Sheet_2_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Data_Sheet_5_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Data_Sheet_3_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Validation and predictive accuracy of the cerebrovascular model, by Hadi Esfandi (21387211)

“…<p>(a-f) dependency of blood flow in capillaries on the cortical depth and ABNP values: (a) mean and standard deviation of blood flow in Cap1 segments for various ABNP values, (b) layer-specific average blood flow in capillaries across the entire monophasic flat autoregulation range, (c) indicates that the superficial layers have a more nonuniform hemodynamic distribution in capillaries, (d) mean capillary blood flow across different vascular layers at physiological ABNP values (50-70 mmHg), (e) WT changes in superficial PA segments are more significant than in deeper segments across the autoregulation range. …”