Showing 21 - 40 results of 98,904 for search '(( 50 ((teer decrease) OR (nn decrease)) ) OR ( 5 ((fold decrease) OR (a decrease)) ))', query time: 1.34s Refine Results
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    Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

    Published 2022
    “…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC<sub>(tofacitinib, 0–∞)</sub> and a 9.61-fold increase of colonic AUC<sub>(tofacitinib, 0–12h)</sub>, compared with tofacitinib at a molar equivalent oral dose. …”
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    Four-fold decrease in [H<sup>+</sup>]<sub>e</sub> shifted GLT-1a E<sub>rev</sub> by −18 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

    Published 2015
    “…Arrows show GLT-1a E<sub>rev</sub> shifts. <b>(C)</b> Average GLT-1 E<sub>rev</sub> shifts at 37.5 μM and 600 μM are approximately equal when [H<sup>+</sup>]<sub>e</sub> was decreased from 40 to 10 nM.…”
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    Four-fold decrease in [K<sup>+</sup>]<sub>e</sub> shifted GLT-1a E<sub>rev</sub> by +22 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

    Published 2015
    “…Arrows show GLT-1a E<sub>rev</sub> shifts. <b>(C)</b> Average GLT-1 E<sub>rev</sub> shifts at 37.5 μM and 600 μM are approximately equal when [K<sup>+</sup>]<sub>e</sub> was decreased from 44 to 11 mM.…”
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    Effects of ROCK inhibitors H-1152 and Y-27632 on TNF-induced MLC phosphorylation, actin and CL5 reorganization and the fall in TEER. by Paul R. Clark (714064)

    Published 2015
    “…D) Effects of H-1152 and Y-27632 on the phase 1 and phase 2 TEER decreases induced by TNF. Starting at T<sub>0</sub>, HDMEC plated on ECIS 96-well arrays received a 1 hour pre-treatment with vehicle (top panel, n = 4, 4) or with a ROCK inhibitor, either H-1152 (at 1 or 10 μM, middle panel, n = 6, 6) or Y-27632 (at 1 or 10 μM, bottom panel, n = 6, 6). …”
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    S1 Fig - by Asadollahi Parisa (8837432)

    Published 2020
    Subjects:
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    Requirement of NF-κB activation for cytokine-mediated reductions in TEER. by Paul R. Clark (714064)

    Published 2015
    “…Note that Bay 11 and SR-IκB each prevented the induction of ICAM-1 as well as the induction of a disrupted pattern of anti-CL5 immunofluorescence staining (arrows in D and E) by TNF. …”
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