GCase protein and activity in diltiazem-treated mice: by Ying Sun (23237)

“…D409H livers had ∼1.2-fold increases of GCase activity. GCase activity in V394L liver decreased 38% after treatment. No significant changes in GCase activity were detected in WT, D409H and V394L brain, spleen, and lung. …”

ZnT1, MT and ZnT4 are all involved in the activation process of TNAP. by Shigeyuki Fujimoto (473814)

“…<p>(<b>A</b>) TNAP activity decreased in DT40 cells deficient in genes coding for c<i>ZnT1</i>, c<i>MT</i> and/or c<i>ZnT4</i> (<i>upper panel</i>). …”

Pyruvate oxidase-deficiency increases susceptibility of <i>Spn</i> to OSCN^-. by Aaron D. Gingerich (9188396)

“…<p><b>(A)</b> H₂O₂ generation was quantitated in wild-type and <i>spxB</i>-deficient (Δ<i>spxB</i>) TIGR4 <i>Spn</i> strains using the Ros-GLo^TM luminescence H₂O₂ quantitation kit. Mean, n = 2. <b>(B)</b> OSCN^—mediated (1st line™) killing of the TIGR4 Δ<i>spxB Spn</i> strain was measured by the microplate-based growth assay in presence or absence of catalase (n = 5). …”

EPIMIC: A Simple Homemade Computer Program for Real-Time EPIdemiological Surveillance and Alert Based on MICrobiological Data by Philippe Colson (73139)

“…Among them, 172,180 were found to be positive for a pathogen. EPIMIC generated a mean number of 0.5 alert/week on abnormal events.…”

Antihypertensive treatment and blood pressure trends among South African adults: A repeated cross-sectional analysis of a population panel survey by Annibale Cois (3229185)

“…</p><p>Results</p><p>During the study period, the prevalence of antihypertensive treatment rose from 13.1% to 17.6% among women and from 5.3% to 8.2% among men. Concurrently–despite worsening trends in major biobehavioural risk factors for elevated blood pressure–mean SBP decreased in both genders, DBP decreased among women and was stable among men. …”

Efficient trypanosome motility requires mechanical interaction with obstacles similar to red blood cells. by Niko Heddergott (120004)

“…Wider spacing led to a sharp decrease in directional motility. (<i>C</i>) The dynamics of the cells net directional movement as represented by the mean squared displacement (MSD) plotted over the observation time points to a fast, super-diffusive swimming behavior in pillar arrays of 4 µm spacing. …”

Reduction of cell viability via FINs is (partially) reversed by deferoxamine mesylate and ferrostatin-1. by Dino Bekric (16475280)

“…(A) Cell viability data is shown as mean values +/- SEM of n = 3 biological replicates of CCC-5 cells with FINs (light grey) and FINS + cell death inhibitors (dark grey) treatment for 24 h. …”

Aging and wave-component latency delays in oVEMP and cVEMP: a systematic review with meta-analysis by Ysa Karen dos Santos Macambira (12814547)

“…For the n23 component, the mean latency delay for the elderly was 2.82 ms with 95% CI of 0.33-5.30 ms. …”

Table_1_Magnetic Non-invasive Auricular Acupuncture During Eye-Exam for Retinopathy of Prematurity in Preterm Infants: A Multicentre Randomized Controlled Trial.DOC by Kimberly M. L. Gan (9912195)

“…Placebo infants had significantly higher PIPP scores during [mean difference 1.6 points (95%CI 0.1–3.1)] and 1 h mean difference 1.5 points (95%CI 0.7–2.2) after the procedure (p < 0.03). …”

Yorkie and the Hippo Pathway Regulate Tracheal Tube Size. by Renée M. Robbins (600671)

“…<p>(A–D) Maximum projections of confocal sections showing tracheal lengths. Compared to stage 16 WT embryos (A), <i>yki^B5</i> mutant trachea (B) have an over-elongated phenotype similar to the SJ mutant <i>sinu</i> (D). …”

Exercise training reverse autonomic dysfunction and hypertension in rats fed with high-fat diet by Carla Cristina de Sordi (4704676)

“…The HFD-T group showed lower systolic (125.3 ( 1.9 mmHg), diastolic (88.5 ( 2.0 mmHg) and mean BP (100.3 ± 2.5 mmHg) in comparison with HFD-S (153.8 ( 3.7; 103.5 ( 2.6 and 120.5 ± 3.7 mmHg; p<0.05, respectively). …”

DSB formation is altered in <i>dot-1</i>.<i>1</i> mutant worms. by Laura I. Lascarez-Lagunas (8275293)

“…Scale bar, 5 μm. <b>(B)</b> Histogram shows the mean number of RAD-51 foci/nucleus (y-axis) scored along each zone in the germlines (x-axis) of the indicated genotypes. …”

CB₂R recruits the cAMP/PKA Pathway as a Downstream Effector. by Gabriel Duff (443819)

“…(A) Representative photomicrographs. Scale bar, 5 µm. (B) Quantification of cAMP fluorescence intensity at the <i>cnr2^+/+</i> growth cone indicates a significant decrease in cAMP levels following treatment with JWH133 and JWH015 while the opposite was observed following stimulation with AM630, JTE907 or FSK. …”

UNC-62 binds to and activates expression of all six <i>C. elegans</i> yolk protein genes. by Eric L. Van Nostrand (30730)

“…(D) All six vitellogenin genes decrease expression with age (as assayed by whole-worm microarrays of 2, 5, 8, and 11 day old adult worms <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>). …”

Inhibition of autocrine TGFβ2 signaling prevents reduction of capillary morphogenesis by miR-30b. by Grant A. Howe (2558611)

“…<p>(A) HUVECs were serum starved overnight in MCDB 131 with 0.5% FBS and stimulated with VEGF (50 ng/ml) in the presence or absence of Avastin (1 μg/ml) for 24 hours. …”

PACSIN2 is required for TcdA uptake and toxin-induced rounding in wildtype MEF cells. by Ramyavardhanee Chandrasekaran (3394916)

“…Data represent mean and SD of 101 individual cells. Student’s t test ***p<0.0001. …”

Models spontaneously develop separate modules for ‘vector-‘ and ‘transition’-based strategies. by Denis C. L. Lan (21807775)

“…Lesioning ‘vector’ units leads to a decrease in use of ‘direction’ actions and lesioning ‘transition’ units leads to a decrease in use of ‘state’ actions. …”

Image_1_Opposite trends in incidence of breast cancer in young and old female cohorts in Hungary and the impact of the Covid-19 pandemic: a nationwide study between 2011–2020.jpeg... by Zoltán Kiss (5570003)

“…Age-standardized mortality rates varied between 26.65–24.97/100,000 PYs (mean annual change: -0.58%; 95% CI: -1.31–0.27%; p=0.101; total change: -5.98%; 95% CI: -13.36–2.66). …”

DataSheet_1_Opposite trends in incidence of breast cancer in young and old female cohorts in Hungary and the impact of the Covid-19 pandemic: a nationwide study between 2011–2020.x... by Zoltán Kiss (5570003)

“…Age-standardized mortality rates varied between 26.65–24.97/100,000 PYs (mean annual change: -0.58%; 95% CI: -1.31–0.27%; p=0.101; total change: -5.98%; 95% CI: -13.36–2.66). …”

Learning over time for C condition by Yoky Matsuoka (31878)