FIGURE 3 from Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial–mesenchymal Transition in Aggressive Variant Prostate Cancers by Taraswi Mitra Ghosh (16616796)

“…<b>B,</b> Apoptosis (caspase 3/7 assay): Levels of caspase 3/7 enzyme (a marker of apoptosis) activities measured followed CONV-TOPO, CONV-DTX, METRO-TOPO, and the combination of CONV-DTX + METRO-TOPO 72 hours treatment. …”

Table_3_“Longitudinal Fecal Microbiome Study of Total Body Irradiated Mice Treated With Radiation Mitigators Identifies Bacterial Associations With Survival”.xlsx by Kelvin Li (158276)

“…Survival improved relative to control (30.0%) for G-CSF (80%, p-value = 0.025), G-CSF/JP4-039 (70%, p-value = 0.084), but not for JP4-039 (50.0%). In the second experiment, mice were administered mitigation drugs “inhibiting programmed cell death” pathways: JP4-039 (anti-apoptosis), necrostatin-1 (anti-necroptosis), and baicalein (anti-ferroptosis), in eight combinations. …”

DataSheet1_Selective Photocatalytic Oxidation of Glycerol and 3-Pyridinemethanol by Nanotube/Nanowire-Structured TiO2 Powders Obtained by Breakdown Anodization.docx by Sıdıka Çetinkaya (12536077)

“…<p>Nanotube/nanowire-structured TiO₂ was formed on the Ti surface by an anodic oxidation method performed at different potential values (50 or 60 V) and for different times (3 or 5 h). …”

Table_1_“Longitudinal Fecal Microbiome Study of Total Body Irradiated Mice Treated With Radiation Mitigators Identifies Bacterial Associations With Survival”.docx by Kelvin Li (158276)

“…Survival improved relative to control (30.0%) for G-CSF (80%, p-value = 0.025), G-CSF/JP4-039 (70%, p-value = 0.084), but not for JP4-039 (50.0%). In the second experiment, mice were administered mitigation drugs “inhibiting programmed cell death” pathways: JP4-039 (anti-apoptosis), necrostatin-1 (anti-necroptosis), and baicalein (anti-ferroptosis), in eight combinations. …”

M disrupts the interaction between ATG14 and BECN1. by Ruonan Zhang (358761)

“…<p>(A) Y2H assays showing the ATG14-N terminal interact with M. …”

Table_1_Effect of short-term mindfulness-based stress reduction on sleep quality in male patients with alcohol use disorder.DOCX by Yongmei Wang (105230)

“…</p>Objective<p>The aim of the present study was to evaluate the effect of short-term MBSR on sleep quality in male patients with AUD after withdrawal.</p>Methods<p>A total of 91 male patients with AUD after 2 weeks of routine withdrawal therapy were randomly divided into two groups using a coin toss: the treatment group (n = 50) and the control group (n = 41). …”

DataSheet1_Phytochemical characterization of Typha domingensis and the assessment of therapeutic potential using in vitro and in vivo biological activities and in silico studies.pd... by Rizwana Dilshad (17354662)

“…TDME demonstrated significant (p < 0.05) potential in analgesic activity by hot plate and tail immersion tests and anti-inflammatory activity by the carrageenan-induced hind paw edema model. Pain latency decreased significantly, and the anti-inflammatory effect increased in a dose-dependent way. …”

Species- and life-stage-specific thermosensory behaviors and thermal physiology. by Ben T. Gregory (20442502)

“…<i>elegans</i> adults display a noxious heat escape response and have a very decreased lifespan, brood size, and hatching viability [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref034" target="_blank">34</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref037" target="_blank">37</a>–<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref039" target="_blank">39</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref042" target="_blank">42</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref043" target="_blank">43</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref050" target="_blank">50</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref069" target="_blank">69</a>].…”

Figure 5 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6A KO decreases Ewing sarcoma tumor growth. <b>A,</b> Colony formation assay of KDM6A KO cells (sgRNA#1 and sgRNA#2) compared with parental cells and sgCTRL in A-673. …”

Tapered Multiblock Copolymers Based on Farnesene and Styrene: Impact of Biobased Polydiene Architectures on Material Properties by Christian Wahlen (1768180)

“…The one-pot, tapered copolymer approach was used to synthesize series of tri- (ABA) and pentablock (ABABA) copolymers of styrene (A) and β-farnesene (B), varying the polydiene volume fraction between 0.50 and 0.68, respectively. …”

Meta data of <i>In vitro</i> and <i>In vivo</i> experiments. by Mohammad Abdullah Taher (18691717)

“…The extract showed broad-spectrum antibacterial activity, with strongest inhibition against <i>Pseudomonas aeruginosa</i> (19 mm) and <i>Salmonella typhi</i> (19 mm), though 30–50% less potent than standard antibiotics. In antidiarrheal testing, 400 mg/kg dose reduced diarrheal episodes by 58.06% compared to control, while in analgesic assay it decreased writhing by 59.18%. …”

ENPP1 Affects Insulin Action and Secretion: Evidences from <em>In Vitro</em> Studies by Rosa Di Paola (158545)

“…<div><p>The aim of this study was to deeper investigate the mechanisms through which ENPP1, a negative modulator of insulin receptor (IR) activation, plays a role on insulin signaling, insulin secretion and eventually glucose metabolism. …”

The core model with an additional intracellular feedback is superior and gene expression upon downregulation of IRF family members. by Katharina Robichon (8445099)

“…(<b>H</b>) Gene expression upon decreased <i>IRF8</i> expression. Huh7.5 cells were incubated with 50 nM siRNA directed against <i>IRF8</i> (red), against <i>IRF8</i> and <i>IRF2</i> (lilac) or non-targeting control (blue) for 24 hours, and then treated with 500 U/ml IFNα. …”

Data_Sheet_1_Increased fruit intake is associated with reduced risk of depression: evidence from cross-sectional and Mendelian randomization analyses.docx by Zhaoqi Yan (11322876)

“…Fruit intake was also associated with a decreased risk of neuroticism traits related to depression, including feeling lonely (OR = 0.82, 95% CI = 0.74–0.90; p = 2.91E-05), feeling miserable (OR = 0.79, 95% CI = 0.72–0.87; p = 2.35E-06), feeling fed-up (OR = 0.75, 95% CI = 0.68–0.83; p = 2.78E-08), irritable mood (OR = 0.89, 95% CI = 0.79–0.99; p = 0.03), and neuroticism (OR = 0.85, 95% CI = 0.76–0.96; p = 9.94E-03). …”

Expression of RIO kinases is associated with EGFR and Akt activity in GBM cells. by Renee D. Read (268044)

“…(G) Neurosphere cultures treated for 24 hours with DMSO or indicated inhibitors. P110 inhibitors: 50 µM LY294002, 1 µM BEZ-235, 2 µM GDC-0941 <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003253#pgen.1003253-Raynaud1" target="_blank">[71]</a>, 2 µM PI-103 <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003253#pgen.1003253-Raynaud1" target="_blank">[71]</a>. …”

Plasma MicroRNAs as Potential Noninvasive Biomarkers for In-Stent Restenosis by Meijiao He (666387)

“…</p><p>Methods</p><p>This retrospective, observational single-centre study was conducted at the cardiovascular department of a tertiary hospital centre in the north of China. …”

Enhanced drug resistance suppression by serum-stable micelles from multi-arm amphiphilic block copolymers and tocopheryl polyethylene glycol 1000 succinate by Lei He (143930)

“…<p><b>Aim:</b> To develop a robust drug-delivery system using multi-arm amphiphilic block copolymers for enhanced efficacy in cancer therapy.…”

Cif redirects CFTR from recycling endosomes to the lysosomal, degradative pathway. by Jennifer M. Bomberger (226715)

“…Purified OMV from <i>P. aeruginosa</i> (PA14), a recently isolated laboratory strain, and clinical isolates (CF and pseudomonal pneumonia) applied to airway epithelial cells for 90 minutes decreased cell lysate and apical membrane abundance of CFTR. …”

Data_Sheet_2_Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspr... by Qian Zhu (191342)

“…<p>This study evaluated the effects of maternal probiotics and synbiotics addition on several traits and parameters in offspring. A total of 64 Bama mini pigs were randomly allocated into the control (basal diet), antibiotic (50 g/t virginiamycin), probiotics (200 mL/day probiotics), or synbiotics (500 g/t xylo-oligosaccharides and 200 mL/day probiotics) group and fed with experimental diets during pregnancy and lactation. …”

Data_Sheet_1_Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspr... by Qian Zhu (191342)

“…<p>This study evaluated the effects of maternal probiotics and synbiotics addition on several traits and parameters in offspring. A total of 64 Bama mini pigs were randomly allocated into the control (basal diet), antibiotic (50 g/t virginiamycin), probiotics (200 mL/day probiotics), or synbiotics (500 g/t xylo-oligosaccharides and 200 mL/day probiotics) group and fed with experimental diets during pregnancy and lactation. …”