Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Fixation becomes unlikely with decreasing fitness of mutant homozygotes, variance in allele frequency increases with migration rate. by Philipp M. Altrock (340203)

IL-1Ra treatment decreases activity and increases rest time in <i>mdx</i> mice. by Margaret E. Benny Klimek (2805361)

Adding AGPAT2 and DGKα to CHO-GPAT1 cells decreased PPARγ activity. by Cliona M. Stapleton (352965)

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on early cytokine response after cecal ligation and puncture (CLP)-induced sepsis. by Daniel Siegl (717509)

LY411,575 decreases infection of hepatic cells by <i>P. berghei</i> ANKA sporozoites. by Iana Parvanova (12738)

MxB decreases the nuclear γH2AX foci induced by L1 retrotransposition. by Yu Huang (15093)

Decreased apoptotic cell death in H9c2 cells treated with OA (caspase activity). by Rudo F. Mapanga (302485)

CNS-<i>Actb</i>KO mice exhibited hyperactivity and decreased performance in the Morris water maze. by Thomas R. Cheever (226943)

<i>Syx5</i> suppression in <i>Drosophila</i> S2 cells decreases copper accumulation. by Melanie Norgate (234832)

Loss of Runx1 in <i>mdx</i> mice decreases muscle mass, muscle strength and lifespan. by Kfir Baruch Umansky (783699)

Inability of macrophages to respond to IL-10 results in decreased persistence of <i>B. abortus in vivo</i>. by Mariana N. Xavier (133803)

H₂O₂ decreases podocyte expression of SD molecules. by Xiqian Lan (219539)

The S75A mutation of LeishIF4E3 leads to a decrease in granule formation in response to PBS starvation and to a reduced interaction with LeishIF4G-4. by Rohit Shrivastava (6459608)

Sustained and repetitive HQ-induced oxidative injury decreases on MCP-1 expression in human RPE cells. by Marianne Pons (355277)

Simulated regional mean wetland seasons. by Nic Gedney (19762301)

SCU decreases ischemia area, improves endothelium-dependent vasodilation and influence of PKG inhibitor in MIR rats. by Lin Li (28817)

Male exposure in ewes decreased the content of <i>Tac2</i> mRNA in the rostral ARC. by Julie-Ann P. De Bond (383668)

Blockade of mTORC2 decreased TRPC6-dependent calcium influx in podocytes (confocal microscopy). by Fangrui Ding (659863)

“…Each trace represents the mean value that was derived from 3 cells or fields in a single experiment. …”

Activation of mitoK_ATP channels decreased the latency time of the transjunctional currents in slice. by Jiangping Wang (281901)

“…The control experiment is shown in (<b>A1</b>). (<b>B</b>) Bar graph shows that at 6 min after exposure to DIZ, the latency time was decreased by 50% with an average of 234.54±34.43 µs (n = 13). …”