Composition of basal diet. by Mahmoud Ghazaghi (18397236)

“…Five supplemental levels (0.05, 0.10, 0.15, 0.20, and 0.25% of diet) of DL-Met or nano-Met were added to a basal diet containing 0.35% standardized ileal digestible (SID) methionine to create 11 experimental diets, including a basal diet and 10 experimental diets containing 0.40, 0.45, 0.50, 0.55, and 0.60% SID-Met, respectively. …”

Data Sheet 3_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo... by Xirui Xia (12075476)

“…</p>Results<p>The results show that compound 16C has low toxicity (LD₅₀ > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T_1/2kel) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”

Assessment of liver pathology in C57BL/6 mice at the end of 4 weeks of normal protein diet (NPD, control diet) or low protein diet (LPD, malnutrition diet) feeding during the first... by Prasad S. Dalvi (405608)

“…The liver triglyceride levels in the LPD-fed mice were significantly decreased post-recovery as compared with the malnutrition period (All data are presented as means ± SD, n ≥ 4 mice per group, *<i>P</i> < 0.05, ***<i>P</i><0.001, ^†††<i>P</i> < 0.001 vs. …”

DataSheet_1_Dynamics of IgG antibody response against Plasmodium antigens among Nigerian infants and young children.pdf by Colleen M. Leonard (12199196)

“…Seropositivity showed a similar decline with the lowest seropositivity against AMA1 and PfMSP1 at 10-12 months, though remaining above 50% during the first 2 years of life in higher transmission areas. …”

Temporal distribution of <i>P</i>. <i>vivax</i> malaria episodes and immune response targeting region II of the Duffy binding protein (DBPII), Rio Pardo Settlement, Amazonas, Brazi... by Flora S. Kano (548431)

“…(<b>C</b>) DBPII binding inhibitory antibodies (BIAbs) had a slightly decreased frequency at the 12 months follow-up examination. …”

Negative regulation of protein-coding genes suggests increased genomic auto-immunity of <i>D</i>. <i>simulans</i> alleles. by Luyang Wang (476973)

“…<p>(A) The number of genes whose expression levels are decreased/increased (>1.5 fold, blue/red) in the presence of each transgene as compared to the corresponding mutant. …”

Table1_Effectiveness of early heparin therapy on outcomes in critically ill patients with sepsis-induced coagulopathy.docx by Jia-Jia Huang (243641)

“…Further analysis showed that treatment with 6,250–13750 IU/day of unfractionated heparin associated with a decreased risk of intensive care unit mortality. …”

Table 1_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. MAFLD mice induced by a high-fat diet were treated with TFA at doses of 50 and 100 mg/kg. …”

Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. MAFLD mice induced by a high-fat diet were treated with TFA at doses of 50 and 100 mg/kg. …”

DataSheet_1_Temperature and elevated CO2 alter soybean seed yield and quality, exhibiting transgenerational effects on seedling emergence and vigor.docx by Naflath Thenveettil (19262185)

“…When the growing temperature increased from optimum to high, the seed oleic acids increased (63%), while linoleic and linolenic acids decreased (- 28% and - 43%, respectively). Significant temperature and CO₂ effects were observed in progenies with the highest maximum seedling emergence (80%), lesser time to 50% emergence (5.5 days), and higher seedling vigor from parents grown at low-temperature treatment under eCO₂.…”

<i>Fgf20</i> is necessary for formation of the lateral compartment of the organ of Corti. by Sung-Ho Huh (191072)

“…Total numbers of hair cells were decreased by 50% in <i>Fgf20^βGal/βGal</i> cochlea. …”

Image_1_BML-111 Reduces Neuroinflammation and Cognitive Impairment in Mice With Sepsis via the SIRT1/NF-κB Signaling Pathway.TIF by Shangwen Pan (5648291)

“…Boc-2 (50 μg/kg) was administered intracerebroventricularly 30 min before CLP, and EX527 (10 μg) was administered every 2 days for a total of three times before CLP, also intracerebroventricularly. …”

Methodology flow chart. by Sidra Aman Rana (14167473)

“…<div><p>Domestic water availability is intricately linked with a growing population, urbanization, and associated land use/land cover change (LULCC). …”

eIF3f regulated rRNA stability through hnRNP K. by Fushi Wen (175725)

“…(D) Silencing of hnRNP K decreased rRNA. Predesigned hnRNP K siRNA (50 nM, Eurogentec) was transfected into MiaPaCa-2 cells using Lipofectamine. rRNA and hnRNP K mRNA fold changes compared to control RNAi cells were assessed by real time RT-PCR after 48 hours. …”

Fig 10 - by Narasimha M. Beeraka (12189587)

“…BT-474 cells with cisplatin/oxaliplatin treatment: expression of FN3K, Nrf2, and Keap1 was not completely declined with cisplatin but NQO1, and HO-1 expression was mitigated at higher concentrations; interestingly, oxaliplatin downregulated the expression of FN3K and Nrf2 consequently mitigated expression of antioxidant proteins such as NQO1 and HO-1. 1-deoxy-1-morpholinofructose (DMF) (dissolved in 50% ethanol), a competitive inhibitor of FN3K, was used as a positive control which could only inhibit ∼10% of total FN3K activity but the FN3K expression was not decreased upon DMF treatment [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0283705#pone.0283705.ref012" target="_blank">12</a>]. …”

Supplementary Figure 1: Antibodies validated for routinely processed tissue unpredictably stain frozen tissue sections by Giorgio Cattoretti (568042)

“…Antigen retrieval (AR) was performed by placing the sections in a 800 ml glass container filled with the retrieval solutions (10 mM EDTA in Tris-buffer pH 8, Merck), irradiate in a household microwave oven at full speed for 8 min, followed by intermittent electromagnetic radiation to maintain constant boiling for 1min., 5 min. or 20 min., and cooling the sections to about 50Co before use. …”

Luminescent Hydrido-Carbonyl Clusters of Rhenium Containing Bridging 1,2-Diazine Ligands by Monica Panigati (1734016)

“…In the case of <b>4a</b>, a blue shift and an increase of the emission intensity were observed upon decreasing the solvent polarity.…”

Model sensitivity analysis to parameters: <i>k</i>_<i>τ</i>, <i>τ</i>_<i>max</i>, <i>F</i>_<i>p</i>, <i>F</i>_<i>c</i>, <i>K</i><sub><i>r</i... by Dharsan K. Soundarrajan (11632145)

“…<i>e</i>., 50% of a BV of 1.5 μM would simulate a value of 0.75 μM). …”

Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs. by Ignacio E. Schor (120406)

“…S5</a>). Orange boxes mark regions with peaks appearing at 2 h TSA and not further increasing, or even decreasing, at 6 h (MALAT1 peaks). …”

Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe... by Huiyu Xu (12255545)

“…A two-parameter logistic curve allowed translation of ovarian reserve scores into an “endocrine age” and enabled individualized prediction of future milestones, such as diminished reserve with ovarian score of 50 and perimenopause, the lowest ovarian reserve score in our ART population. …”