Related to Fig 1. by Amy E. Schade (15368259)

Inhibition of GSK3β rescues impaired myogenesis during myoblast differentiation induced by <i>Optn</i> KD. by Xiao Chen Shi (8611887)

OPTN is essential for myogenesis during skeletal muscle regeneration in response to muscle injury. by Xiao Chen Shi (8611887)

The second-order rate-yield tradeoff demonstrated by decreasing the P/O ratio and and knocking out <i>gnd</i> (“Δ<i>gnd</i>”) in ME-model simulations. by Chuankai Cheng (6791417)

OPTN degrades GSK3β via activating LC3-mediated autophagy. by Xiao Chen Shi (8611887)

Contingency relation between IPI before and IPI after each pulse. by Laura N. Kloepper (8173881)

Flow chart for patients inclusion. by Haruka Imai (3703819)

“…Following this, antibiotic prescription was associated with a decreased 28-day mortality rate (2.3% vs. 3.6%) and in-hospital mortality rate (4.0% vs. 5.0%) compared with the control group. …”

The outcome measures in IPTW analysis. by Haruka Imai (3703819)

“…Following this, antibiotic prescription was associated with a decreased 28-day mortality rate (2.3% vs. 3.6%) and in-hospital mortality rate (4.0% vs. 5.0%) compared with the control group. …”

Locomotion and turning angle sizes of adult <i>D</i>. <i>melanogaster</i>, <i>D</i>. <i>simulans</i>, <i>D immigrans</i>, <i>D</i>. <i>subobscura</i> and <i>D pavani</i> in Petri d... by Jeannette Silva-López (16541854)

<i>F</i>. <i>oxysporum</i> f. sp. <i>albedinis</i> genome code for a large repertoire of secreted proteins. by Maryam Rafiqi (12647200)

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Number of bars of length greater than <i>ℓ</i> = 4000 in the barcodes obtained via the binary model (left) and the fuzzy binary model (right) as a function of <i>τ</i>. by Samir Chowdhury (5715338)

Triclosan Dioxygenase: A Novel Two-component Rieske Nonheme Iron Ring-hydroxylating Dioxygenase Initiates Triclosan Degradation by Yiran Yin (19144130)

“…The highest amino acid identity of TcsA and the large subunits of other dioxygenases in the same family was only 35.50%, indicating that TcsAB is a novel dioxygenase. …”

LDHA is increased in bleomycin-induced pulmonary fibrosis. by Jennifer L. Judge (5278415)

Global positioning system (GPS) tracks. by Prateep Duengkae (7485500)

Water supply head entries, a raw measure of rat’s activity, show rapid increase at the time the lights were turned on at 06:00 but no change at the time the lights were turned off.... by Piotr Popik (292215)

Passive transfer of humanized anti-NS1 mAb 33D2 into DENV-inoculated mice decreases viral titer and NS1 level in mouse sera. by Sen-Mao Tien (12481273)