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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 step » _ step (Expand Search), a step (Expand Search), 2 step (Expand Search)
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5161
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5162
Introducing the 4‑Phenyl-1,2,3-Triazole Moiety as a Versatile Scaffold for the Development of Cytotoxic Ruthenium(II) and Osmium(II) Arene Cyclometalates
Published 2016“…Herein we report the synthesis, anticancer potency <i>in vitro</i>, biomolecule interaction, and preliminary mode of action studies of a series of cyclometalated 1,2,3-triazole-derived ruthenium(II) (<b>2a</b>–<b>e</b>) and osmium(II) (<b>3a</b>–<b>e</b>) organometallics of the general form [(η<sup>6</sup>-<i>p</i>-cym)RuCl(κ<sup>2</sup>-C^N-L)] with varying substituents in postion 1 of the 1,2,3-triazole moiety. …”
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5163
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5164
Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in <i>Trypanosoma cruzi</i>
Published 2017“…Isotretinoin inhibited the polyamine transport, as well as other amino acid transporters from the same protein family (<i>Tc</i>AAAP), with calculated IC<sub>50</sub> values in the range of 4.6–10.3 μM. It also showed a strong inhibition of trypomastigote burst from infected cells, with calculated IC<sub>50</sub> of 130 nM (SI = 920) being significantly less effective on the epimastigote stage (IC<sub>50</sub> = 30.6 μM). …”
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5165
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5166
<i>Bbs1</i><sup><i>M390R/M390R</i></sup> mice have decreased hippocampal proliferation.
Published 2021“…The Red Bar line represents 50μm. G.) Decreased proliferation in the dentate gyrus of P3 <i>Bbs1</i><sup><i>M390R/M390R</i></sup> mice. …”
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5167
Intracellular Delivery of Bioactive Molecules using Light-Addressable Nanocapsules
Published 2010“…We demonstrate this method with the intracellular release of the second messenger IP<sub>3</sub> in CHO-M1 cells and report that calcium responses from the cells changed from a sustained increase to a transient spike when the average number of IP<sub>3</sub> released is decreased below 50 molecules per nanocapsule. …”
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5168
Patient data.
Published 2024“…</p><p>Results</p><p>On average, the time required to move through the obstacle course decreased by 17.0% after the training phase, the number of collisions decreased by 50.0%. …”
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5169
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5170
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5171
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5172
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5173
Reduction of the mean absolute error (MAE) in time for all participant on x-axis.
Published 2019“…<p>A similar effect is observed for y-axis. The MAE obtained using the standard regression (orange circles) decreased significantly when using symbolic regression. …”
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5174
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5175
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5176
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5177
Discovery of Urea Derivatives of Celastrol as Selective Peroxiredoxin 1 Inhibitors against Colorectal Cancer Cells
Published 2024“…Herein, a series of celastrol urea derivatives were developed based on its cocrystal structure with PRDX1, with the aim of pursuing a PRDX1-specific inhibitor. …”
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5178
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5179
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5180