Image_3_Effects of diagnostic ultrasound with cRGD-microbubbles on simultaneous detection and treatment of atherosclerotic plaque in ApoE−/− mice.JPEG by Shengcun Guo (11264265)

“…</p>Methods<p>Three mouse models, apolipoprotein E-deficient mice on a hypercholesterolemic diet (HCD) or normal chow diet and wild-type mice on an HCD were used. …”

Image_1_Effects of diagnostic ultrasound with cRGD-microbubbles on simultaneous detection and treatment of atherosclerotic plaque in ApoE−/− mice.JPEG by Shengcun Guo (11264265)

“…</p>Methods<p>Three mouse models, apolipoprotein E-deficient mice on a hypercholesterolemic diet (HCD) or normal chow diet and wild-type mice on an HCD were used. …”

Molecular Dynamics Reveals Altered Interactions between Belzutifan and HIF‑2 with Natural Variant G323E or Proximal Phosphorylation at T324 by Vishva Natarajan (19481906)

“…Whereas the effects of G323E are concentrated in the binding pocket Fα helix within the HIF-2α PAS-B domain, pT324 decreased the belzutifan binding affinity and stabilized the HIF-2 heterodimer through an alternate mechanism involving polar interactions between the HIF-2α PAS-B and PAS-A domains. …”

Table_1_Effects of diagnostic ultrasound with cRGD-microbubbles on simultaneous detection and treatment of atherosclerotic plaque in ApoE−/− mice.DOCX by Shengcun Guo (11264265)

“…</p>Methods<p>Three mouse models, apolipoprotein E-deficient mice on a hypercholesterolemic diet (HCD) or normal chow diet and wild-type mice on an HCD were used. …”

Presentation_1_Effects of diagnostic ultrasound with cRGD-microbubbles on simultaneous detection and treatment of atherosclerotic plaque in ApoE−/− mice.PDF by Shengcun Guo (11264265)

“…</p>Methods<p>Three mouse models, apolipoprotein E-deficient mice on a hypercholesterolemic diet (HCD) or normal chow diet and wild-type mice on an HCD were used. …”

Distribution of SARS-CoV-2 RNA+ cells in lungs of hamsters after intranasal inoculation with B.1 (614G), B.1.427 and B.1.429 by in-situ hybridization (ISH). by Timothy Carroll (3762841)

Effect of TLR4 siRNA and PDTC treatment on food intake and body weight in CUMS apoE^-/- mice. by Ya Ling Tang (720332)

Data_Sheet_1_Untargeted lipidomics and metagenomics reveal the mechanism of aspirin eugenol ester relieving hyperlipidemia in ApoE−/− mice.docx by Xiao-Rong Lu (14276438)

“…Hence, in this study, we investigated the effects of AEE on liver lipids through LC-MS-based untargeted lipidomics and the effects of AEE on gut microbiota based on cecal contents metagenomics by Illumina sequencing in HFD-induced hyperlipidemia ApoE−/− mice at the overall level. The results of lipidomics showed that AEE relieved hyperlipidemia by decreasing the concentration of 10 PEs and 12 SMs in the liver and regulating the pathways of glycerophospholipid metabolic pathway, sphingolipid signaling pathway, and NF-kB signaling pathway. …”

β3-Adrenoreceptor Stimulation Protects against Myocardial Infarction Injury <i>via</i> eNOS and nNOS Activation by Xiaolin Niu (487869)

“…These results suggested that β3-AR stimulation has a substantial effect on recovery of heart function. …”

Data_Sheet_1_Untargeted lipidomics and metagenomics reveal the mechanism of aspirin eugenol ester relieving hyperlipidemia in ApoE−/− mice.docx by Xiao-Rong Lu (14276438)

“…Hence, in this study, we investigated the effects of AEE on liver lipids through LC-MS-based untargeted lipidomics and the effects of AEE on gut microbiota based on cecal contents metagenomics by Illumina sequencing in HFD-induced hyperlipidemia ApoE−/− mice at the overall level. The results of lipidomics showed that AEE relieved hyperlipidemia by decreasing the concentration of 10 PEs and 12 SMs in the liver and regulating the pathways of glycerophospholipid metabolic pathway, sphingolipid signaling pathway, and NF-kB signaling pathway. …”

Malate treatment did not increase the lifespan of <i>sdha-2</i> and F48E8.3 RNAi knockdown worms. by Clare B. Edwards (385682)

“…(<b>C</b>) 10 mM malate decreased the lifespan of soluble fumarate reductase F48E8.3 RNAi knockdown N2 worms (log-rank <i>p</i> = 0.002). …”

Characterization of Partial Ligation-Induced Carotid Atherosclerosis Model Using Dual-Modality Molecular Imaging in ApoE Knock-out Mice by Ik Jae Shin (387313)

“…</p> <p>Methodology and Principal Findings</p><p>Partial ligation of the left CCA was performed in 10-week-old ApoE^-/- mice on a high fat diet (n=33); the internal and external carotid arteries and occipital artery were ligated, while the superior thyroid artery was left intact. …”

Data_Sheet_1_Divergent Effects of Acute and Prolonged Interleukin 33 Exposure on Mast Cell IgE-Mediated Functions.PDF by Elin Rönnberg (54133)

“…Acute IL-33 treatment strongly potentiated IgE-mediated activation. In contrast, 4 days of exposure to IL-33 decreased IgE-mediated activation, an effect that was accompanied by a reduction in FcεRI expression.…”

Clade III N-AChR show similar agonist affinities. by Jennifer D. Noonan (14117157)

“…<p>Concentration- response curves were measured to determine if declining maximal response is due to decreasing ligand affinity. Concentration-response curves for clade III N-AChRs for (A) acetylcholine and (B) nicotine. …”

Eukaryotic Translation Initiation Factor 3 Subunit E Controls Intracellular Calcium Homeostasis by Regulation of Cav1.2 Surface Expression by Pawel Buda (416558)

“…Here, we used real-time 3D confocal and TIRFM imaging, immunocytochemistry, cellular fractionation, immunoprecipitation and electrophysiology to study trafficking of L-type Ca_V1.2 channels upon β-cell stimulation. We found decreased surface expression of Ca_V1.2 and a corresponding reduction in L-type whole-cell Ca²⁺ currents in insulin-secreting INS-1 832/13 cells upon protracted (15–30 min) stimulation. …”

Temporal regulation of XBP1 mRNA poly(A) tail length during UPR in mouse pancreatic β cells (MIN6) cells. by Mohammed R. Alzahrani (13229154)

Induction of autophagy through CLEC4E in combination with TLR4: an innovative strategy to restrict the survival of <i>Mycobacterium tuberculosis</i> by Susanta Pahari (37943)

“…This study suggests a unique immunotherapeutic approach involving CLEC4E in conjunction with TLR4 to restrict the survival of <i>Mtb</i> through autophagy.…”

Effect of TLR4 siRNA and PDTC treatment on atherosclerotic lesions in aortic sinuses of CUMS apoE^-/- mice. by Ya Ling Tang (720332)

“…(C) Percentage of atherosclerotic lesion areas in entire aorta in apoE^-/- mice. The lesion area in CUMS + siRNA group, and CUMS + PDTC group were significantly decreased than that of CUMS groups, respectively. …”

Table_1_A Short-Term Ketogenic Diet Impairs Markers of Bone Health in Response to Exercise.XLSX by Ida A. Heikura (8333907)

A: MET+5-FU treatment significantly increased the percentage of annexin V+ apoptotic cells as compared with 5-FU alone treatment (Early apoptosis rate: 3.50 ± 0.44 % vs 2.33 ± 0.38... by Yanfei Zhang (488656)