<i>Bmal1</i>-KO exhibit decreased pyknosis, indicative of diminished cell death, in the dentate gyrus relative to heterozygous and wildtype mice. by Brooke D. Rakai (579635)

Survivability is decreased in zebrafish embryos following exogenous treatment with an amino-terminal fragment of nApoE4_1-151. by Madyson M. McCarthy (9238322)

Fig 1 - by Ilari Kuitunen (11084096)

Fig 2 - by Ilari Kuitunen (11084096)

Fig 2 - by Kyu Jin Lee (18143946)

“…<p>In-hospital mortality rates across the quartiles for SI, DSI, MSI, and Age-SI values among patients with normal LVEF (≥ 50%; A, B, C, and D, respectively) and those with decreased LVEF (< 50%; E, F, G, and H, respectively). …”

Fig 4 - by Kyu Jin Lee (18143946)

NatB inactivation decreased the level of MAPK and proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways. by Zhentao Sheng (107495)

Flow chart for the enrolled patients. by Kyu Jin Lee (18143946)

“…Left ventricular (LV) function was categorized as either normal LV ejection fraction (LVEF ≥ 50%) or decreased LVEF (<50%).</p><p>Results</p><p>Among the 1,194 patients with septic shock, 392 (32.8%) who underwent echocardiography within 24 h of time zero were included in the final analysis (normal LVEF: n = 246; decreased LVEF: n = 146). …”

Increased astrogliosis at 4 days of recovery observed in the injured SVZ after H/I is decreased by ALK5 inhibition <i>in vivo</i>. by Jennifer M. Bain (252246)

Over-expression of YKL-40 in 76N MECs decreases E-cad and β-casein, but increases MMP-9 expression and cell invasiveness. by Steve Scully (202724)

The effect of (A) mean sequencing depth (genome coverage) and (B) average number of nucleotide differences per site (<i>π</i>) on accuracy of genetic similarity estimates in simula... by Kevin D. Murray (759583)

Structure–Activity Studies of 1<i>H</i>‑Imidazo[4,5‑<i>c</i>]quinolin-4-amine Derivatives as A₃ Adenosine Receptor Positive Allosteric Modulators by Lucas B. Fallot (14106171)

“…Although having low Caco-2 permeability and high plasma protein binding, hydrophobic 2-cyclohept-4-enyl-<i>N</i>-3,4-dichlorophenyl, MRS7788 <b>18</b>, and 2-heptan-4-yl-<i>N</i>-4-iodophenyl, MRS8054 <b>39</b>, derivatives were orally bioavailable in rat. 2-Heptan-4-yl-<i>N</i>-3,4-dichlorophenyl <b>14</b> and 2-cyclononyl-<i>N</i>-3,4-dichlorophenyl <b>20</b> derivatives and <b>39</b> greatly enhanced Cl-IB-MECA-stimulated [³⁵S]GTPγS binding <i>E</i>_max, with only <b>12b</b> trending toward decreasing the agonist EC₅₀. A feasible route for radio-iodination at the <i>p-</i>position of a 4-phenylamino substituent suggests a potential radioligand for allosteric site binding. …”

Structure–Activity Studies of 1<i>H</i>‑Imidazo[4,5‑<i>c</i>]quinolin-4-amine Derivatives as A₃ Adenosine Receptor Positive Allosteric Modulators by Lucas B. Fallot (14106171)

“…Although having low Caco-2 permeability and high plasma protein binding, hydrophobic 2-cyclohept-4-enyl-<i>N</i>-3,4-dichlorophenyl, MRS7788 <b>18</b>, and 2-heptan-4-yl-<i>N</i>-4-iodophenyl, MRS8054 <b>39</b>, derivatives were orally bioavailable in rat. 2-Heptan-4-yl-<i>N</i>-3,4-dichlorophenyl <b>14</b> and 2-cyclononyl-<i>N</i>-3,4-dichlorophenyl <b>20</b> derivatives and <b>39</b> greatly enhanced Cl-IB-MECA-stimulated [³⁵S]GTPγS binding <i>E</i>_max, with only <b>12b</b> trending toward decreasing the agonist EC₅₀. A feasible route for radio-iodination at the <i>p-</i>position of a 4-phenylamino substituent suggests a potential radioligand for allosteric site binding. …”

Table 1_Association of memory function with COVID-19 outcomes in adults aged 50 years and older: analysis of three prospective cohorts.docx by Juanjuan Shi (8192751)

“…The aORs for COVID-19 mortality were 1.06 (95% CI, 0.93–1.20) and 1.14 (95% CI, 1.01–1.28) per word decrease in immediate and delayed 10-words recall in SHARE, respectively. …”

Local sensitivity analysis of procoagulants, fibrin, F1.2 flux, and TAT flux. by Jason Chen (15937)

High-dose AA treatment decreases IL-6 and HTLV-1 p19 levels in HTLV-1-infected cell line supernatant. by Britta Moens (149041)

Schematic of the reduced model. by Jason Chen (15937)

The potency of the blockage of FXIa varies over the subsets of fibrin concentration. by Jason Chen (15937)

Effect of inhibitory antibodies and human serum on NA enzymatic function ELLA and NA Star. by Harrison Powell (9040128)

Local sensitivity analysis of total thrombin, free, and bound thrombin in the clot. by Jason Chen (15937)