More than two-fold differentially expressed histone demethylases in MC3T3-E1 cells differentiated for 21 days compared to undifferentiated subconfluent cells in RNA-seq analysis. by Petri Rummukainen (4247122)

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Lsd1 inhibitor treatment in vivo. by Petri Rummukainen (4247122)

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Lsd1 ChIP-seq analysis. by Petri Rummukainen (4247122)

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Picrosirius red staining analysis showed no changes in collagen maturation under polarized light between groups. by Petri Rummukainen (4247122)

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Kdm7a gene locus H3K4 methylation and LSD1 binding patterns visualized by integrative genomic viewer (IGV). by Petri Rummukainen (4247122)

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Lsd1 binding correlates with expression status and differential expression. by Petri Rummukainen (4247122)

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Lsd1 inhibition in osteoblasts. by Petri Rummukainen (4247122)

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Examples of H3K4 methylation patterns at Lsd1 bound promoters and enhancers visualized by integrative genomic viewer (IGV). by Petri Rummukainen (4247122)

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Examples of H3K4 methylation patterns at Lsd1 bound promoters and enhancers visualized by integrative genomic viewer (IGV). by Petri Rummukainen (4247122)

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Loss of Lsd1 in long bone mesenchymal cells leads to impaired ossification and growth. by Petri Rummukainen (4247122)

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Lsd1 is abundantly expressed in osteoblasts and important for osteoblast differentiation. by Petri Rummukainen (4247122)

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Loss of Lsd1 in long bone mesenchymal cells disrupts growth plate organization but not collagen maturation. by Petri Rummukainen (4247122)

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Histone ChIP-seq analysis. by Petri Rummukainen (4247122)

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M344 decreases orthotopic pancreatic tumor growth when used as a treatment alone or in combination with gemcitabine. by Shelby M. Knoche (13833807)

Pooled testing schema for testing with Hologic Panther Aptima^® and Fusion^® SARS-CoV-2 assays. by Rudolph Park (14070418)

Simulation results of step-up load variation. by Maged Al-Barashi (18721120)

Experimental results of step-up load variation. by Maged Al-Barashi (18721120)

Foldases and holdases each decrease the level of unfolded protein. by Adam MR de Graff (9767829)

Proteasomal activity decreases with ApoE4 expression. by Nathan R. Zuniga (20422428)

The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …”