Table_2_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.DOCX by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Table_1_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.DOCX by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Species- and life-stage-specific thermosensory behaviors and thermal physiology. by Ben T. Gregory (20442502)

“…<i>elegans</i> adults display a noxious heat escape response and have a very decreased lifespan, brood size, and hatching viability [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref034" target="_blank">34</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref037" target="_blank">37</a>–<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref039" target="_blank">39</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref042" target="_blank">42</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref043" target="_blank">43</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref050" target="_blank">50</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref069" target="_blank">69</a>].…”

Figure 5 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6A KO decreases Ewing sarcoma tumor growth. <b>A,</b> Colony formation assay of KDM6A KO cells (sgRNA#1 and sgRNA#2) compared with parental cells and sgCTRL in A-673. …”

TcdB3 has reduced binding to CSPG4. by Zhenrui Pan (10047214)

“…The percentage of rounded cells were plotted over toxin concentrations. Their CR50 were measured and plotted in a bar chart (I). …”

Table_2_“Longitudinal Fecal Microbiome Study of Total Body Irradiated Mice Treated With Radiation Mitigators Identifies Bacterial Associations With Survival”.xlsx by Kelvin Li (158276)

“…Survival improved relative to control (30.0%) for G-CSF (80%, p-value = 0.025), G-CSF/JP4-039 (70%, p-value = 0.084), but not for JP4-039 (50.0%). In the second experiment, mice were administered mitigation drugs “inhibiting programmed cell death” pathways: JP4-039 (anti-apoptosis), necrostatin-1 (anti-necroptosis), and baicalein (anti-ferroptosis), in eight combinations. …”

FIGURE 3 from Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial–mesenchymal Transition in Aggressive Variant Prostate Cancers by Taraswi Mitra Ghosh (16616796)

“…<b>B,</b> Apoptosis (caspase 3/7 assay): Levels of caspase 3/7 enzyme (a marker of apoptosis) activities measured followed CONV-TOPO, CONV-DTX, METRO-TOPO, and the combination of CONV-DTX + METRO-TOPO 72 hours treatment. …”

Table_3_“Longitudinal Fecal Microbiome Study of Total Body Irradiated Mice Treated With Radiation Mitigators Identifies Bacterial Associations With Survival”.xlsx by Kelvin Li (158276)

“…Survival improved relative to control (30.0%) for G-CSF (80%, p-value = 0.025), G-CSF/JP4-039 (70%, p-value = 0.084), but not for JP4-039 (50.0%). In the second experiment, mice were administered mitigation drugs “inhibiting programmed cell death” pathways: JP4-039 (anti-apoptosis), necrostatin-1 (anti-necroptosis), and baicalein (anti-ferroptosis), in eight combinations. …”

DataSheet1_Selective Photocatalytic Oxidation of Glycerol and 3-Pyridinemethanol by Nanotube/Nanowire-Structured TiO2 Powders Obtained by Breakdown Anodization.docx by Sıdıka Çetinkaya (12536077)

“…<p>Nanotube/nanowire-structured TiO₂ was formed on the Ti surface by an anodic oxidation method performed at different potential values (50 or 60 V) and for different times (3 or 5 h). …”

Table_1_“Longitudinal Fecal Microbiome Study of Total Body Irradiated Mice Treated With Radiation Mitigators Identifies Bacterial Associations With Survival”.docx by Kelvin Li (158276)

“…Survival improved relative to control (30.0%) for G-CSF (80%, p-value = 0.025), G-CSF/JP4-039 (70%, p-value = 0.084), but not for JP4-039 (50.0%). In the second experiment, mice were administered mitigation drugs “inhibiting programmed cell death” pathways: JP4-039 (anti-apoptosis), necrostatin-1 (anti-necroptosis), and baicalein (anti-ferroptosis), in eight combinations. …”

M disrupts the interaction between ATG14 and BECN1. by Ruonan Zhang (358761)

“…<p>(A) Y2H assays showing the ATG14-N terminal interact with M. …”

Table_1_Effect of short-term mindfulness-based stress reduction on sleep quality in male patients with alcohol use disorder.DOCX by Yongmei Wang (105230)

“…</p>Objective<p>The aim of the present study was to evaluate the effect of short-term MBSR on sleep quality in male patients with AUD after withdrawal.</p>Methods<p>A total of 91 male patients with AUD after 2 weeks of routine withdrawal therapy were randomly divided into two groups using a coin toss: the treatment group (n = 50) and the control group (n = 41). …”

DataSheet1_Phytochemical characterization of Typha domingensis and the assessment of therapeutic potential using in vitro and in vivo biological activities and in silico studies.pd... by Rizwana Dilshad (17354662)

“…TDME demonstrated significant (p < 0.05) potential in analgesic activity by hot plate and tail immersion tests and anti-inflammatory activity by the carrageenan-induced hind paw edema model. Pain latency decreased significantly, and the anti-inflammatory effect increased in a dose-dependent way. …”

Tapered Multiblock Copolymers Based on Farnesene and Styrene: Impact of Biobased Polydiene Architectures on Material Properties by Christian Wahlen (1768180)

“…The one-pot, tapered copolymer approach was used to synthesize series of tri- (ABA) and pentablock (ABABA) copolymers of styrene (A) and β-farnesene (B), varying the polydiene volume fraction between 0.50 and 0.68, respectively. …”

Meta data of <i>In vitro</i> and <i>In vivo</i> experiments. by Mohammad Abdullah Taher (18691717)

“…The extract showed broad-spectrum antibacterial activity, with strongest inhibition against <i>Pseudomonas aeruginosa</i> (19 mm) and <i>Salmonella typhi</i> (19 mm), though 30–50% less potent than standard antibiotics. In antidiarrheal testing, 400 mg/kg dose reduced diarrheal episodes by 58.06% compared to control, while in analgesic assay it decreased writhing by 59.18%. …”

The core model with an additional intracellular feedback is superior and gene expression upon downregulation of IRF family members. by Katharina Robichon (8445099)

“…(<b>H</b>) Gene expression upon decreased <i>IRF8</i> expression. Huh7.5 cells were incubated with 50 nM siRNA directed against <i>IRF8</i> (red), against <i>IRF8</i> and <i>IRF2</i> (lilac) or non-targeting control (blue) for 24 hours, and then treated with 500 U/ml IFNα. …”

Data_Sheet_1_Increased fruit intake is associated with reduced risk of depression: evidence from cross-sectional and Mendelian randomization analyses.docx by Zhaoqi Yan (11322876)

“…Fruit intake was also associated with a decreased risk of neuroticism traits related to depression, including feeling lonely (OR = 0.82, 95% CI = 0.74–0.90; p = 2.91E-05), feeling miserable (OR = 0.79, 95% CI = 0.72–0.87; p = 2.35E-06), feeling fed-up (OR = 0.75, 95% CI = 0.68–0.83; p = 2.78E-08), irritable mood (OR = 0.89, 95% CI = 0.79–0.99; p = 0.03), and neuroticism (OR = 0.85, 95% CI = 0.76–0.96; p = 9.94E-03). …”

Enhanced drug resistance suppression by serum-stable micelles from multi-arm amphiphilic block copolymers and tocopheryl polyethylene glycol 1000 succinate by Lei He (143930)

“…<p><b>Aim:</b> To develop a robust drug-delivery system using multi-arm amphiphilic block copolymers for enhanced efficacy in cancer therapy.…”

RNA-seq transcriptomics analysis in human tissue culture cells reveals changes in the expression levels of over 100 nucleolar mRNAs after PAX9 knockdown. by Katherine I. Farley-Barnes (9258036)

“…Of these, 812 mRNAs had a decreased fold change (≤ -2) and 184 of those mRNAs code for proteins designated as nucleolar in at least one of three databases [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008967#pgen.1008967.ref050" target="_blank">50</a>–<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008967#pgen.1008967.ref052" target="_blank">52</a>]. …”

Data Sheet 1_Strategies for enhancing yield and quality of forage-grain dual-purpose ratoon rice: role of first-season density and nitrogen management.docx by Yuyuan Ouyang (15350374)

“…FY498 reached the highest yield under D3N3 (48.46-57.60 t ha⁻¹), while CKYSM performed best under D2N3 (45.39-50.93 t ha⁻¹). Elevated density and nitrogen levels increased acid detergent fiber and neutral detergent fiber contents and reduced starch, indicating a decline in overall silage quality, though crude protein improved. …”