NC enhances intracellular ox-LDL degradation through facilitation of lipophagy. by Hong-Feng Gu (287123)

CDA deficiency leads to excess dCTP, inhibiting PARP-1 activity and leading to UFB formation. by Simon Gemble (168663)

“…(G) (1) CDA deficiency leads to intracellular dCTP accumulation, decreasing basal PARP-1 activity. (2) The decrease in basal PARP-1 activity leads to an increase in unreplicated DNA sequences (preferentially at centromeres and CFS sites). (3) During late G2/early mitosis, some of this unreplicated DNA is probably processed by MUS81-EME1 and ERCC1 nucleases as previously suggested [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005384#pgen.1005384.ref036" target="_blank">36</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005384#pgen.1005384.ref012" target="_blank">12</a>], leading to DNA synthesis during metaphase (EdU foci) and preventing supernumerary UFB formation. (4) Some of the excess unreplicated DNA sequences are not processed by the nucleases, leading to supernumerary UFB formation.…”

Immunocytochemistry showing localization of P53, P21, NF-κB p50, NF-κB p65 and MMP-9 in presence and absence of CY2 in HCT116 cells. by Sumit Kumar Dey (385318)

“…<p>DAPI was used for genomic DNA counterstaining (A) Translocation status of P53 and P21 in control cells (upper panel) and 20 µM CY2 treated cells (lower panel). …”

Table_1_The Myelin Water Fraction Serves as a Marker for Age-Related Myelin Alterations in the Cerebral White Matter – A Multiparametric MRI Aging Study.docx by Tobias D. Faizy (3142110)

Correlations between the percentage of total sperm motility and GABA A-α1 receptor expression in sperm. by Paweena Kaewman (14329011)

The contribution of CNVs, SNVs and Indels in patient’s receiving a diagnosis. by Kimberly Gall (11372216)

Formation and Characteristics of Lipid-Blended Block Copolymer Bilayers on a Solid Support Investigated by Quartz Crystal Microbalance and Atomic Force Microscopy by Mudassar Mumtaz Virk (4717590)

A Multicenter Phase I/II Study of Obatoclax Mesylate Administered as a 3- or 24-Hour Infusion in Older Patients with Previously Untreated Acute Myeloid Leukemia by Aaron D. Schimmer (150194)

“…Obatoclax was increased to 45 mg/day (3 h×3 d) if ≤1 patient had a dose-limiting toxicity (DLT) and decreased to 20 mg/day (3 h×3 d) if DLT occurred in ≥2 patients. …”

Abnormal visual experience-induced homeostatic synaptic plasticity in GluR1-S831A mutants. by Anubhuti Goel (225953)

“…<p><b>(A)</b> Left: average mEPSC amplitude decreased with dark-exposure (D) and did not decrease any further with re-exposure to light (L). *: Significantly different from NR (N) at p<0.01, Fisher's PLSD posthoc test. …”

The ventral striatum is robustly activated during a child-friendly reward task in the MTwiNS sample (<i>n</i> = 464). by Melissa K. Peckins (12042132)

The ventral striatum is robustly activated during a child-friendly reward task in the ABC brains sample (<i>n</i> = 27). by Melissa K. Peckins (12042132)

Effects of A1AR expression on response to hypoxia at E9.5 and E12.5. by Daniela L. Buscariollo (140729)

“…<p>A: At E9.5, responses to hypoxia in A1AR −/− (n = 15) and A1AR +/− (n = 50) embryos were studied. …”

S4 Fig - by R. J. S. D. Heine (17889199)

“…In the scenario analysis the profit margin contributed most to a higher CBPs for both drugs. Lower estimates resulted from assumed lower R&D costs.…”

S1 Fig - by R. J. S. D. Heine (17889199)

“…In the scenario analysis the profit margin contributed most to a higher CBPs for both drugs. Lower estimates resulted from assumed lower R&D costs.…”

S5 Fig - by R. J. S. D. Heine (17889199)

“…In the scenario analysis the profit margin contributed most to a higher CBPs for both drugs. Lower estimates resulted from assumed lower R&D costs.…”

S3 Fig - by R. J. S. D. Heine (17889199)

“…In the scenario analysis the profit margin contributed most to a higher CBPs for both drugs. Lower estimates resulted from assumed lower R&D costs.…”

S6 Fig - by R. J. S. D. Heine (17889199)

“…In the scenario analysis the profit margin contributed most to a higher CBPs for both drugs. Lower estimates resulted from assumed lower R&D costs.…”

Input parameters for the base-case analysis. by R. J. S. D. Heine (17889199)

“…In the scenario analysis the profit margin contributed most to a higher CBPs for both drugs. Lower estimates resulted from assumed lower R&D costs.…”

S1 Data - by R. J. S. D. Heine (17889199)

“…In the scenario analysis the profit margin contributed most to a higher CBPs for both drugs. Lower estimates resulted from assumed lower R&D costs.…”

Microscopical lesions in trachea and lungs H&E staining on dpi 10. A) Moderate to severe subacute tracheitis (score 2) with epithelial hyperplasia (Asterisk) and mixed inflammatory... by Oumayma Arbani (21001472)