Analysis of bile salt sensitivity and LPS profiles in the wild-type and <i>bipA</i>-deleted strains of <i>E. coli</i> and <i>S</i>. Typhimurium. by Eunsil Choi (8271039)

An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals by Dominique Detaille (3768979)

“…<div><p>Findings</p><p>Here, we demonstrate that OP2113 (5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione, CAS 532-11-6), synthesized and used as a drug since 1696, does not act as an unspecific antioxidant molecule (i.e., as a radical scavenger) but unexpectedly decreases mitochondrial reactive oxygen species (ROS/H₂O₂) production by acting as a specific inhibitor of ROS production at the I_Q site of complex I of the mitochondrial respiratory chain. …”

20E repressed ILP-mediated cell membrane translocation of HaP60 and HaP110, dephosphorylated HaP60 and HaP110, and decreased their interaction. by Yu-Qin Di (8752317)

“…Green, HaP60 or HaP110; red, cell membrane stained with WGA; blue, nuclei stained with DAPI; merge, overlapped green, blue, and red fluorescence. Bar, 50 μm. <b>C.</b> Co-IP assay showed that 20E decreased the HaP60–HaP110 interaction and induced dephosphorylation in cells. …”

Δ3C virus-induced lymphomas have decreased expression of E2F target genes. by James C. Romero-Masters (4112614)

Knockdown of VPg and eIF4E protein interactions decreased the levels of RHDV translation. by Jie Zhu (126574)

Decreased echinocandin susceptibility in <i>Candida parapsilosis</i> causing candidemia and emergence of a pan-echinocandin resistant case in China by Yating Ning (11264310)

Distribution Coefficients of the REEs, Sr, Y, Ba, Th, and U between α‑HIBA and AG50W-X8 Resin by Haoyu Li (1672648)

“…For all 19 elements, the distribution coefficients decrease with increasing acid concentration. For the REEs, a linear relationship is observed in log–log space between <i>K</i>_d values and α-HIBA molarity. …”

CXCL8 (200 pg/ml) and CCL20 (500 pg/ml) affected osteoblast-to-osteoclast communication at day 14. by Janak L. Pathak (759122)

Olaparib reverses the oxLDL-mediated decrease in co-immunoprecipitation of IκBα with RelA or p50. by Khamis Mustafa (17941332)

“…Relative band densities from three independent experiments were analyzed. (A) OxLDL decreased co-immunoprecipitation of IκBα with both RelA and p50, and olaparib reversed the effect of oxLDL on the dissociation of IκBα with RelA and p50. …”

Proteasome inhibition equivalently affects <i>C</i>. <i>trachomatis</i> growth in HeLa and C33A during arginine starvation. by Shardulendra P. Sherchand (3133677)

Table S1 - Inhibition of Lipoprotein-Associated Phospholipase A2 Ameliorates Inflammation and Decreases Atherosclerotic Plaque Formation in ApoE-Deficient Mice by Wen-yi Wang (207256)

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma by Zhihao Liu (419349)

“…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …”

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma by Zhihao Liu (419349)

“…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …”

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma by Zhihao Liu (419349)

“…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …”

Effect of CXCL8 (200 pg/ml), CCL20 (500 pg/ml), CXCL8-CM, and CCL20-CM on osteoclast formation. by Janak L. Pathak (759122)

Pretreatment with SDG prevents iron induced decrease in H9c2 cell size. by Stephanie Puukila (568109)

Additional tryptophan metabolite alterations in response to a control diet or a diet containing MCOA: a. by Natalie E. Diether (16705804)

High-dose thiamine prevents brain lesions and prolongs survival of <i>Slc19a3</i>-deficient mice by Kaoru Suzuki (4217638)

“…To investigate the molecular mechanisms of neurodegeneration in SLC19A3 deficiency and whether administration of high-dose thiamine prevents neurodegeneration, we generated homozygous Slc19a3 E314Q knock-in (KI) mice harboring the mutation corresponding to the human SLC19A3 E320Q, which is associated with the severe form of THMD2. …”

Occurrences of the hemoglobin safety composite endpoint (hemoglobin decrease of ≥40 g/L or ≥40% versus baseline or hemoglobin <50 g/L or blood transfusion) by G6PD genotype in the... by Zul Premji (215008)

Arginine starvation impacts <i>C</i>. <i>trachomatis</i> development in HeLa and C33A cells to an equivalent extent. by Shardulendra P. Sherchand (3133677)