Hormone addition results in chromatin changes at individual GR-regulated genes. by Chuong D. Pham (111374)

“…We calculate that a nucleosome/bare ratio of 1.0 corresponds to ∼50% nucleosome occupancy, while a value of 2.1 corresponds to 100% occupancy (e.g. a nucleosome covering a given location on all gene copies). …”

Brivanib inhibits liver fibrosis induced by thioacetamide. by Ikuo Nakamura (548298)

“…(B) The number of bands of bridging fibrosis per high power field were counted in images obtained at 100× magnification after Sirius red staining. There was a significant decrease in the number of bands in both the 25 mg/kg and 50 mg/kg brivanib groups, compared to placebo. …”

Collagen XVI overexpression leads to an increase of ILK/kindlin-1 interaction. by Konstanze B. Bedal (513309)

“…<p>(<b>A</b>) Proximity ligation assay for the analysis of ILK/kindlin-1 interaction in COLXVI and mock control cells (scale bar equals 50 µm). …”

The effect of dopamine on Δψ_m and [Ca²⁺]_c in midbrain neurons and astrocytes. by Sonia Gandhi (49260)

“…Furthermore this increase in [Ca²⁺]_c is associated with a reduction in ΔΨ_m. Application of 50 mM KCl induces a further rise in [Ca²⁺]_c and profound mitochondrial depolarisation. …”

Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)^† by Vandana Purohit (2947848)

“…Finally, when the primer had a 3‘-OH, a fluorescence decrease with a rate equal to the rate of nucleotide incorporation was observed with both 0 and +1 position reporters. …”

<em>Bacillus anthracis</em> Interacts with Plasmin(ogen) to Evade C3b-Dependent Innate Immunity by Myung-Chul Chung (226513)

“…PLG-bound spores were capable of exhibiting anti-opsonic properties by cleaving C3b molecules <em>in vitro</em> and in rabbit bronchoalveolar lavage fluid, resulting in a decrease in macrophage phagocytosis. Our findings represent a step forward in understanding the mechanisms involved in the evasion of innate immunity by <em>B. anthracis</em> through recruitment of PLG resulting in the enhancement of anti-complement and anti-opsonization properties of the pathogen.…”

An Inducible Cell-Cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors by Alon Herschhorn (198447)

“…<div><p>HIV-1 envelope glycoproteins (Envs) mediate virus entry by fusing the viral and target cell membranes, a multi-step process that represents an attractive target for inhibition. …”

Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)^† by Vandana Purohit (2947848)

“…Finally, when the primer had a 3‘-OH, a fluorescence decrease with a rate equal to the rate of nucleotide incorporation was observed with both 0 and +1 position reporters. …”

Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)^† by Vandana Purohit (2947848)

“…Finally, when the primer had a 3‘-OH, a fluorescence decrease with a rate equal to the rate of nucleotide incorporation was observed with both 0 and +1 position reporters. …”

The role of cell density on drug response in multilayered cell culture. by Maria Håkanson (154559)

“…Using the same experimental setup, we found that proliferation in monolayers decreased with increasing cell density (E). A significant decrease in proliferation compared to a sub-confluent situation was observed at a cell density of 86 cells per pattern. …”

RES complex is associated with intron definition and required for zebrafish early embryogenesis by Juan Pablo Fernandez (5478497)

“…<div><p>Pre-mRNA splicing is a critical step of gene expression in eukaryotes. …”

Multistep Interactions between Ibuprofen and Lipid Membranes by Simou Sun (3089832)

“…Ibuprofen (IBU) interacts with phosphatidylcholine membranes in three distinct steps as a function of concentration. In a first step (<10 μM), IBU electrostatically adsorbs to the lipid headgroups and gradually decreases the interfacial potential. …”

Multistep Interactions between Ibuprofen and Lipid Membranes by Simou Sun (3089832)

“…Ibuprofen (IBU) interacts with phosphatidylcholine membranes in three distinct steps as a function of concentration. In a first step (<10 μM), IBU electrostatically adsorbs to the lipid headgroups and gradually decreases the interfacial potential. …”

Multistep Interactions between Ibuprofen and Lipid Membranes by Simou Sun (3089832)

“…Ibuprofen (IBU) interacts with phosphatidylcholine membranes in three distinct steps as a function of concentration. In a first step (<10 μM), IBU electrostatically adsorbs to the lipid headgroups and gradually decreases the interfacial potential. …”

Multistep Interactions between Ibuprofen and Lipid Membranes by Simou Sun (3089832)

“…Ibuprofen (IBU) interacts with phosphatidylcholine membranes in three distinct steps as a function of concentration. In a first step (<10 μM), IBU electrostatically adsorbs to the lipid headgroups and gradually decreases the interfacial potential. …”

Multistep Interactions between Ibuprofen and Lipid Membranes by Simou Sun (3089832)

“…Ibuprofen (IBU) interacts with phosphatidylcholine membranes in three distinct steps as a function of concentration. In a first step (<10 μM), IBU electrostatically adsorbs to the lipid headgroups and gradually decreases the interfacial potential. …”

Data overview for continuous imagery duration. by Daphne Cuvelier (561619)

Relationships between leaf toughness and litter chemical trait changes (as fractions of final / initial) in amounts or in concentrations under different environment conditions. by Xu Pan (517723)

Alterations of Marginal Zone (MZ) B cells during <i>T. brucei</i> infections. by Magdalena Radwanska (73816)

Correlation between stored patterns affects sequence completion in the DDN model. by Mehdi Bayati (5819342)