mTORC1 hyperactivation led to a decreased autophagic activity in the podocytes. by Wakiko Iwata (8600457)

“…<p>(<b>A</b>) Primary cultured podocytes were isolated from <i>Tsc2</i>^{Δ<i>podocyte</i>} and wild-type controls, followed by western blot analyses of TSC2, phospho-4EBP1, LC3B type II, p62, phospho-ULK1, and β-tubulin. …”

ACT-induced decrease of macrophage adhesion. by César Martín (229306)

The concentration-dependent decrease of intracellular D-Ser concentrations produced by incubation of PC-12 cells with the enantiomers of ketamine (Ket) and its major metabolites ex... by Nagendra S. Singh (2620399)

Propofol induced cell death and decreased mitochondrial membrane potential in a concentration- and time-dependent manner. by Chisato Sumi (3521705)

Lymphocytes decreased in mouse pneumonia model. by Qi Xu (134661)

At lower concentrations, METH decreases LTP. by Jarod Swant (246454)

“…At 0.1 µM METH, LTP was 1.58±.08 [<i>n</i> = 13(5)] (Fig. 1B); at 1 µM METH, LTP was 1.50±.07 [<i>n</i> = 13(7)] (Fig. 1C); at 10 µM METH, LTP was 1.58±.07 [<i>n</i> = 14(8)] (Fig. 1D); at 30 µM METH, LTP was 1.37±.06 [<i>n</i> = 15(4)] (Fig. 1E); and at 60 µM METH, LTP was 1.32±.24 [<i>n</i> = 4(2)] (Fig. 1E). …”

AKT inhibition decreases neuroblast populations. by Maria R. Aburto (186884)

“…Otic vesicles were isolated from HH18 chicken embryos, made quiescent and cultured for 20 h in serum-free culture medium without additions (0S, a) or in the presence of IGF-I (10 nM, b), LY294002 (LY, 25 µM, c) or AKTi VIII (AKTi, 50 µM, d). …”

2-ME decreases blood pressure in Sprague Dawley rats. by Weiyu Chen (2216251)

2-APB decreased the expression of maturation markers in human DC. by Romain Félix (586765)

The rate of lariat formation is decreased two-fold by isoginkgetin treatment. by Jesse M. Gray (527662)

“…The indicated values are from an average of three biological replicates, and <i>p</i>-values are from two-tailed <i>t</i>-tests based on mean values for aggregated introns 2–10 (n = 9). …”

Decreased oligodendrocyte precursor number in developing white matter tracts. by Mark D. Grier (726986)

Repetitive stress induces a decrease in sound-evoked activity. by Ghattas Bisharat (20706928)

“…These mice exhibited a minimal change in noise-evoked PPy activity when comparing the first and second week of imaging (2-way ANOVA, F = 1.79, <i>p</i> = 0.11, post hoc baseline w1 50 dB: baseline w2 50 dB <i>p</i> = 1 Bonferroni corrected, nested ANOVA (mouse nested within session) F = 1.76, <i>p</i> = 0.12, mean ± SE). …”

Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction by Jin Chai (183630)

“…Conversely, the expression levels of liver detoxification enzymes, UGT2B4/7, SULT2A1, GSTA1-4, and GSTM1-4, were reduced by approximately 50% (p<0.05) in human obstructive cholestasis. …”

Decrease in GABA_A immunoreactivity in APP mice. by Ksenia V. Kastanenka (3692380)

“…(<b>D</b>) Voltage-sensitive dye traces showing a decrease in power of slow oscillations 60 minutes after topical application of 50 μM picrotoxin to a 4 month old wildtype mouse brain. …”

miR-105 results in decreased Cdk6 expression at both the mRNA and protein levels. by D. Rice Honeywell (442714)

“…<p>(A–B) PC3 cells were transfected with 50 nM miR-105 or control mimics as described in materials and methods and relative levels of Cdk6 expression were assessed over time. …”

Calyculin A-induced decrease of tyrosine-monophosphorylated ERK2 at high cell density. by Noriyuki Kawabata (3391739)

The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …”

C2GnT1 gene knockdown decreases C2-O-sLe^X glycoproteins and C2GnT1 activity. by Catherine A. St. Hill (357388)

“…Note the absence of a detected C2GnT1 protein 50 kDa band. (D) We observed a 30–40% decrease in reactivity with CHO-131 mAb by flow cytometry for LS174T and HepG2 cells that contained C2GnT1 shRNA. …”

Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…<p>VCaP cells were transfected for 72h from 2.5 nM to 50 nM with siRNA TMPRSS2-ERG III, siRNA TMPRSS2-ERG IV or siRNA Control. …”

Decrease in extracellular Zn²⁺ in the hippocampus by zinc chelators. by Atsushi Takeda (18203)

“…<p>Hippocampal slices were prepared 2 h after i.p. injection of vehicle (A, n = 7) or CQ (30 mg/kg, B, n = 5) into NER, and 3 h after i.p. injection of vehicle (C, n = 7) or TPEN (1 mg/kg, D, n = 8) into NER. …”