Tradeoffs in resistance to two antibiotics. by Ellsworth M. Campbell (313943)

“…With the highest tradeoff constraint and <i>ω</i> = 1, <i>MICA</i>₃ and <i>MICB</i>₃ equal zero and are same as the <i>MICA_S</i> and <i>MICB_S</i> values for sensitive <i>S</i> bacteria (○). As <i>ω</i> is decreased from 1.0, 0.75, 0.50, 0.25 to 0, the progression (→) represents the double-resistant <i>R</i>₃ experiencing less and less tradeoff. …”

Genotoxic Mechanisms of Erythrophleum suaveolens Stem Bark Extracts and Fractions in MCF-7 Breast Cancer Cells via Mitochondrial and Non-Mitochondrial Pathways by Lateef Sulaimon (21706283)

“…After 72 hours, ESSB-treated MCF-7 cells showed a significant (p < 0.05) increase in DNA fragmentation and comet tail DNA percentages (flavonoids induced a 1.21-fold increase in comet tail length). …”

DataSheet1_CYP2D6 gene polymorphism and apatinib affect the metabolic profile of fluvoxamine.docx by Zhize Ye (13583515)

“…Meanwhile, the produce of desmethyl fluvoxamine was dramatically inhibited, both AUC and C_max decreased significantly. Mechanistically, apatinib inhibit the generation of fluvoxamine metabolite with a mixed manner both in RLM and HLM. …”

Data_Sheet_1_Selenium Effect Threshold for Soil Nematodes Under Rice Biofortification.xlsx by Jiaping Song (317369)

“…In this study, a rice pot experiment was carried out to test how selenite supply (untreated control (0), 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 100, or 200 mg Se kg⁻¹) in soil affected rice growth, rice Se accumulation, and soil nematode abundance and composition. …”

Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo‑<i>p</i>‑dioxin by Rance Nault (3847747)

“…Phosphatidylserines, phosphatidylethanolamines, phosphatidic acids, and cardiolipins decreased 4.1-, 5.0-, 5.4- and 7.4-fold, respectively, while ceramides increased 6.6-fold. …”

Clock function in EO neurons is not required for synchronization to temperature cycles in constant darkness. by Clara Lorber (14106749)

“…C) Percentage of flies decreasing their locomotion with a slope steeper (blue), or lower (orange) than 50% of the theoretical slope after the morning peak at DD2 following DDTC. …”

Table 1_Screening and identification of the H1R antagonists from natural products by BODIPY FL histamine recognition and DPHD-anchored bombardment coupled with target cell extracti... by Xinqi Li (14029494)

“…The BODIPY FL histamine recognition results revealed the significant blocking effects on H1R binding by pseudoephedrine (50 μM) and dictamnine (100 μM). Pseudoephedrine (200 μM) and dictamnine (100 μM) markedly decreased the histamine-induced increase in intracellular calcium ion (Ca²⁺) concentration. …”

Table 1_Mechanism of action of Butein in cutaneous squamous cell carcinoma through regulation of the TWEAK-FN14 signaling pathway.docx by Qinyi Dong (22824800)

“…</p>Results<p>Molecular docking predicted that Butein exhibits strong binding affinity with TWEAK, FN14, cIAP1, and TRAF1/2 proteins, with binding energies ranging from −5.8 to −6.9 kcal/mol.In vitro experiments demonstrated that Butein inhibited the proliferation and migration of human cSCC cell line A431 with an IC₅₀ of 43 μM and induced dose-dependent apoptosis. …”

Effect of nitrogen levels and nitrogen ratios on lodging resistance and yield potential of winter wheat (<i>Triticum aestivum</i> L.) by Mingwei Zhang (661218)

“…A field experiment with Yangmai 20 as research material (a widely-used variety) was conducted to study the effects of different nitrogen levels and ratios on culm morphological, anatomical characters and chemical components and to explore the nitrogen application techniques for lodging tolerance and high yield. …”

Table 1_Cross-cultural adaptation and validation of the Spanish version of the Prevent for Work questionnaire.docx by Julia Blasco-Abadía (18774070)

“…</p>Methods<p>The first phase consisted of a forward-and-backward translation process and evaluating the face-validity of the questionnaire among 30 Spanish workers. …”

Relative membrane levels of endogenous endoglin in HMEC-1 cells upon transient or stable mutant protein expression. by Tassilo Förg (606727)

“…In comparison to non-transfected HMEC-1 control cells, mutant expression resulted in a total reduction of endogenous membrane endoglin by 50–60%. …”

Image_2_Combination Treatment With Remdesivir and Ivermectin Exerts Highly Synergistic and Potent Antiviral Activity Against Murine Coronavirus Infection.tif by Yu Ling Tan (11210325)

“…Murine hepatitis virus (MHV) is a coronavirus that infects mice and shares some sequence identity to SARS-CoV-2. …”

Data Sheet 1_Silicon (Si) foliar treatment modulates Capsicum annuum L. (green chilli) growth and stress responses under cadmium and lead stress.docx by Waquar Akhtar Ansari (7056191)

“…For instance, at 100 mg kg⁻¹, Cd and Pb significantly reduced the seed germination (62.5% and 50%), vigor indices (67.2% and 56.8%), root biomass (88% and 66%), chlorophyll a (75.5% and 55.5%) and carotenoids (56.4% and 48.7%) in chilly plants. …”

Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…Only two serious adverse events were reported (one hyperkalemia and one decreased white blood cell count).</p>Conclusion<p>This real-world study supports the effectiveness and safety of serplulimab-based regimens as a first-line treatment for patients with locally advanced or metastatic esophageal cancer, regardless of their diverse characteristics.…”

Data_Sheet_1_Metabolic characterization of phosphate solubilizing microorganisms and their role in improving soil phosphate solubility, yield of upland rice (Oryza sativa L.), and... by Betty Natalie Fitriatin (12793829)

“…The greenhouse experiment used a factorial randomized block design (RBD) with two factors and three replications. …”

Data_Sheet_1_New insights into the evaluation criteria for high-quality deep marine shale gas reservoirs in the Longmaxi formation: Evidence from organic matter pore development ch... by Boyuan Zhu (12754736)

“…Microscopic and macroscopic indications from OM pores show that a large number of OM pores were developed in high-quality reservoirs. …”

Triple mutants reveal <i>mef2ca</i> modifier epistasis. by Juliana Sucharov (8067371)

“…Removing functional copies of <i>jag1b</i> from <i>mef2ca;dlx5a</i> double mutants decreases penetrance of <i>mef2ca</i>-associated phenotypes. …”

Feasibility Study of Using Gemstone Spectral Imaging (GSI) and Adaptive Statistical Iterative Reconstruction (ASIR) for Reducing Radiation and Iodine Contrast Dose in Abdominal CT... by Zheng Zhu (487587)

“…CT dose index (CTDI) values for non-enhanced, arterial phase and portal phase in group A were decreased by 49.04%, 40.51% and 40.54% compared with group B (P = 0.000), respectively. …”

Encoding in Balanced Networks: Revisiting Spike Patterns and Chaos in Stimulus-Driven Systems - Fig 7 by Guillaume Lajoie (3544997)

“…(<b>E</b>) Tempotron’s performance <i>P</i> against the cumulative inclusion of neurons where the spike times were strongly jittered (±50 milliseconds). Different lines indicate three orderings of neurons the neurons that were jittered, based on their trained readout weight <i>w</i>_<i>i</i>: (i) decreasing, (ii) increasing and (iii) random. …”

Table 1_Comparative transcriptomic and molecular biology analyses to explore potential immune responses to Vibrio parahaemolyticus challenge in Eriocheir sinensis.docx by Duanduan Chen (6860495)

“…The results showed that intramuscular injection of 1.78 × 10⁶ CFU/mL of V. parahaemolyticus for 24 hours resulted in a 50% mortality rate among the experimental animals. …”