Proteomic Sample Preparation through Extraction by Unspecific Adsorption on Silica Beads for ArgC-like Digestion by Yannik Lewin (6326420)

“…When combined with ArgC-like digestion, this approach delivered 5386 uniquely identified proteins, a substantial increase of 18.27% over tryptic digestion (4554), while decreasing spectra complexity due to a lower number of peptide to spectra matches per protein and the number of missed cleaved peptides. …”

Epigenetic changes in the early stage of silica-induced cell transformation by Carole Seidel (1854136)

“…Short-term treatment by Min-U-Sil^® 5 decreased global DNA methylation and increased the expression of the two <i>de novo</i> DNMTs, DNMT3a and DNMT3b. …”

Characterization and conventional identification of ATPS compared to conventional methods. by Hyunwoo Shin (758074)

“…<p>(<b>A</b>) Additional purification steps of serial protein-depletion. …”

Hyperparameter settings. by Qingnan Ji (22662198)

“…Integration efficiency increases by 18.7%, and computational complexity is significantly reduced, with average computation time decreased by 15.4%. User satisfaction also improves, with a 19.5% increase in experience ratings. …”

Increased Expression Levels of WAVE3 Are Associated with the Progression and Metastasis of Triple Negative Breast Cancer by Swati Kulkarni (87840)

“…We have identified the WAVE3 protein, which is a critical regulator of actin cytoskeleton dynamics that are required for the motility and invasion of cancer cells through its activation of the Arp2/3 complex, as a key regulator of the different steps of the invasion-metastasis cascade in BC, especially in the more aggressive TNBCs. …”

An overview of bioinformatics workflow and statistical analysis performed on antibody HTS datasets. by Ulrike Menzel (561225)

“…<p>(A) Bioinformatics steps following the HTS of antibody libraries and preceding the data analysis. …”

Meiotic Crossover Control by Concerted Action of Rad51-Dmc1 in Homolog Template Bias and Robust Homeostatic Regulation by Jessica P. Lao (360701)

“…This function of Dmc1 is independent of Hed1, but requires the meiotic kinase, Mek1. Hed1 makes a relatively minor contribution to homolog bias, but nonetheless this is important for normal morphogenesis of synaptonemal complexes and efficient crossing-over especially when DSB numbers are decreased. …”

Initial weight values and correlation thresholds. by Qingnan Ji (22662198)

“…Integration efficiency increases by 18.7%, and computational complexity is significantly reduced, with average computation time decreased by 15.4%. User satisfaction also improves, with a 19.5% increase in experience ratings. …”

Ablation experiment results comparison. by Qingnan Ji (22662198)

“…Integration efficiency increases by 18.7%, and computational complexity is significantly reduced, with average computation time decreased by 15.4%. User satisfaction also improves, with a 19.5% increase in experience ratings. …”

Curve of data size vs. running time. by Qingnan Ji (22662198)

“…Integration efficiency increases by 18.7%, and computational complexity is significantly reduced, with average computation time decreased by 15.4%. User satisfaction also improves, with a 19.5% increase in experience ratings. …”

Data (3). by Qingnan Ji (22662198)

“…Integration efficiency increases by 18.7%, and computational complexity is significantly reduced, with average computation time decreased by 15.4%. User satisfaction also improves, with a 19.5% increase in experience ratings. …”

Structure of the Kuhn-Munkres Algorithm. by Qingnan Ji (22662198)

“…Integration efficiency increases by 18.7%, and computational complexity is significantly reduced, with average computation time decreased by 15.4%. User satisfaction also improves, with a 19.5% increase in experience ratings. …”

Data_Sheet_1.doc by Annika Wahl (4384339)

“…The replicated results indicate that, in addition to genes encoding for glycosyltransferases (i.e., ST6GAL1, B4GALT1, FUT8, and MGAT3), other genetic loci have strong influences on the IgG glycosylation patterns. A novel locus on chromosome 1, harboring RUNX3, which encodes for a transcription factor of the runt domain-containing family, is associated with decreased galactosylation. …”

Image_3.jpeg by Annika Wahl (4384339)

“…The replicated results indicate that, in addition to genes encoding for glycosyltransferases (i.e., ST6GAL1, B4GALT1, FUT8, and MGAT3), other genetic loci have strong influences on the IgG glycosylation patterns. A novel locus on chromosome 1, harboring RUNX3, which encodes for a transcription factor of the runt domain-containing family, is associated with decreased galactosylation. …”

Image_4.jpeg by Annika Wahl (4384339)

“…The replicated results indicate that, in addition to genes encoding for glycosyltransferases (i.e., ST6GAL1, B4GALT1, FUT8, and MGAT3), other genetic loci have strong influences on the IgG glycosylation patterns. A novel locus on chromosome 1, harboring RUNX3, which encodes for a transcription factor of the runt domain-containing family, is associated with decreased galactosylation. …”

Image_6.jpeg by Annika Wahl (4384339)

“…The replicated results indicate that, in addition to genes encoding for glycosyltransferases (i.e., ST6GAL1, B4GALT1, FUT8, and MGAT3), other genetic loci have strong influences on the IgG glycosylation patterns. A novel locus on chromosome 1, harboring RUNX3, which encodes for a transcription factor of the runt domain-containing family, is associated with decreased galactosylation. …”

Image_2.jpeg by Annika Wahl (4384339)

“…The replicated results indicate that, in addition to genes encoding for glycosyltransferases (i.e., ST6GAL1, B4GALT1, FUT8, and MGAT3), other genetic loci have strong influences on the IgG glycosylation patterns. A novel locus on chromosome 1, harboring RUNX3, which encodes for a transcription factor of the runt domain-containing family, is associated with decreased galactosylation. …”

Image_5.jpeg by Annika Wahl (4384339)

“…The replicated results indicate that, in addition to genes encoding for glycosyltransferases (i.e., ST6GAL1, B4GALT1, FUT8, and MGAT3), other genetic loci have strong influences on the IgG glycosylation patterns. A novel locus on chromosome 1, harboring RUNX3, which encodes for a transcription factor of the runt domain-containing family, is associated with decreased galactosylation. …”

Image_1.jpeg by Annika Wahl (4384339)

“…The replicated results indicate that, in addition to genes encoding for glycosyltransferases (i.e., ST6GAL1, B4GALT1, FUT8, and MGAT3), other genetic loci have strong influences on the IgG glycosylation patterns. A novel locus on chromosome 1, harboring RUNX3, which encodes for a transcription factor of the runt domain-containing family, is associated with decreased galactosylation. …”

Table_1_Awareness of episodic memory and meta-cognitive profiles: associations with cerebrospinal fluid biomarkers at the preclinical stage of the Alzheimer’s continuum.docx by David López-Martos (18695614)

“…The role of SCD and the dyadic contingency was explored with the corresponding stratified analysis.</p>Results<p>CSF Aβ42/40 was non-linearly associated with meta-memory, showing an increased awareness up to Aβ-positivity and a decreased awareness beyond this threshold. …”