Tissue repair Tregs are reduced in target tissues and lymphoid organs during acute <i>T</i>. <i>cruzi</i> infection. by Santiago Boccardo (5927954)

IL-33 supplementation fails to prevent trTreg reduction in established <i>T</i>. <i>cruzi</i> infection. by Santiago Boccardo (5927954)

Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

“…The preliminary mechanistic studies indicated that compounds <b>6</b> and <b>43</b> possibly target the HAdV DNA replication process, while compounds <b>46</b> and <b>47</b> suppress later steps of HAdV life cycle. Notably, among these derivatives, compound <b>15</b> showed improved anti-HAdV activity (IC₅₀ = 0.27 μM), significantly decreased cytotoxicity (CC₅₀ = 156.8 μM), and low <i>in vivo</i> toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide, supporting its further <i>in vivo</i> efficacy studies for the treatment of HAdV infections.…”

Effect of thalidomide on CUL5 and NEDD8 localization in HUVEC. by Bryan Kunkler (5204327)

(S)-(-)-blebbistatin O-benzoate reduces mast cell infiltration in AD-like lesions of NC/Nga mice. by Shunya Sahara (836432)

“…(S)-(-)-blebbistatin O-benzoate treatment significantly decreased mast cell numbers. Data represent mean ± SE, *<i>p</i> < 0.05 vs. vehicle.…”

FAT1 controls degradation of YAP and TAZ proteins in MDA-MB-231 and U-87 cells. by Rui Li (4631)

FAT1 controls degradation of YAP and TAZ proteins in HN13 and CAL27 cells. by Rui Li (4631)

FAT1 controls degradation of YAP and TAZ proteins. by Rui Li (4631)

PAMAM-DEN^CYS induces trafficking of ΔF508-CFTR to plasma membrane in CF cells. by Scott Mackenzie Brockman (4433614)

“…Data represent mean ± SEM of triplicate samples. (F) Immunofluorescence microscopy of HEK-293 cells transfected with ΔF508-CFTR and treated with PAMAM-DEN^CYS (500μM, 12 hrs) show increased plasma membrane (PM, yellow arrows) trafficking of CFTR with decreased peri-nuclear aggresome-bodies (AB, red arrows) as compared to controls. …”

Regulation of YAP/TAZ through MIB2 in HNSCCs. by Rui Li (4631)

Passenger mutations accurately classify human tumors by Marina Salvadores (6589187)

“…In particular, introducing the RMD features into a combined classification model increased the fraction of diagnosed patients by 50 percentage points (at 20% FDR). …”

Homotransplantation of Engineered Macrophages with Surface-Modified Nanomedicines for Mitigating Myocardial Ischemia–Reperfusion Injury by Jiahui Cheng (6056966)

Homotransplantation of Engineered Macrophages with Surface-Modified Nanomedicines for Mitigating Myocardial Ischemia–Reperfusion Injury by Jiahui Cheng (6056966)

Homotransplantation of Engineered Macrophages with Surface-Modified Nanomedicines for Mitigating Myocardial Ischemia–Reperfusion Injury by Jiahui Cheng (6056966)

IFN-γ limits trTreg expansion both <i>in vitro</i> after IL-33 stimulation and <i>in vivo</i> during <i>T</i>. <i>cruzi</i> infection. by Santiago Boccardo (5927954)

Distributions of genomic features across multiple colorectal cancer and tuberculosis studies. by Yilin Gao (4335571)

Knockdown of the <i>Trpv1</i> gene in ARC POMC neurons blocks the anorexigenic effect of capsaicin. by Jae Hoon Jeong (215351)

Workflow for integrating multiple simulated heterogeneous metagenomic datasets. by Yilin Gao (4335571)

DataSheet1_Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.docx by Shukun Sun (11510686)

“…</p><p>Results: ADK inhibition notably attenuated the severity of SAP, as indicated by the decreased serum amylase (7,416.76 ± 1,457.76 vs. 4,581.89 ± 1,175.04 U/L) and lipase (46.51 ± 11.50 vs. 32.94 ± 11.46 U/L) levels and fewer pancreatic histopathological alterations (histological scores: 6.433 ± 0.60 vs. 3.77 ± 0.70). …”

Experimental Study on Water-in-Oil Emulsion Stability Induced by Asphaltene Colloids in Heavy Oil by Fatemeh Mahmoudi Alemi (10312321)

“…However, predicting and controlling the stability of these emulsions under varying conditions remains a challenge. In this study, we investigated the formation and stability of water−oil emulsions under both atmospheric and high-pressure, high-temperature (HPHT) conditions, with a focus on the role of asphaltenes and interfacial tension (IFT). …”