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15921
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15922
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15923
Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat...
Published 2025“…Meanwhile, compared with placebo, evolocumab (MD −1.89, 95% CI −2.27 to −1.50), alirocumab (MD −1.83, 95% CI −2.09 to −1.57), rosuvastatin (MD −1.93, 95% CI −2.30 to −1.56), inclisiran (MD −1.68, 95% CI −2.10 to −1.27), and atorvastatin (MD −1.68, 95% CI −2.04 to −1.31) could also play a role in the treatment of LDL-C reduction. …”
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15924
Neuronal responses to visual stimuli in the proposed microcircuit model with different excitatory/inhibitory (E/I) ratios caused by a change in parvalbumin (PV) inhibitory interneu...
Published 2025“…<p>Note that the total number of model neurons in the network remained consistent, irrespective of E/I ratio. <b><i>A.</i></b> Mean population firing rates of Pyr (black triangles in first panel from the left), PV (gray circles in the second panel), somatostatin (SOM; gray pentagons in the third panel), and vasoactive intestinal polypeptide (VIP; gray diamonds in the fourth panel) populations as a function of E/I ratios. …”
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15925
4a.obj from The three-dimensional flower-like Bi<sub>2</sub>WO<sub>6</sub> assisted by ethanolamine through microwave method for efficient photocatalytic activity
Published 2019“…The three-dimensional flower-like Bi<sub>2</sub>WO<sub>6</sub> was synthesized through one-step microwave method (the reaction temperature was 434 K and the reaction took 10 min), with the assist of ethanol amine. …”
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15926
3a.opj from The three-dimensional flower-like Bi<sub>2</sub>WO<sub>6</sub> assisted by ethanolamine through microwave method for efficient photocatalytic activity
Published 2019“…The three-dimensional flower-like Bi<sub>2</sub>WO<sub>6</sub> was synthesized through one-step microwave method (the reaction temperature was 434 K and the reaction took 10 min), with the assist of ethanol amine. …”
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15927
Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
Published 2024“…FindingsIn 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). …”
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15928
datasheet1_Antihypertensive Effect of a Novel Angiotensin II Receptor Blocker Fluorophenyl Benzimidazole: Contribution of cGMP, Voltage-dependent Calcium Channels, and BKCa Channel...
Published 2021“…</p><p>Results: FPD significantly decreased blood pressure in SHR. It relaxed superior mesenteric arteries in a concentration-dependent manner and significantly inhibited angiotensin II-induced contraction. …”
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15929
Data Sheet 1_Impact of early enteral nutrition on the prognosis of mechanically ventilated patients with chronic obstructive pulmonary disease: a retrospective cohort study based o...
Published 2025“…However, the EEN group exhibited a significantly shorter duration of mechanical ventilation (127.50 vs. 137.94 h, p = 0.023), reduced ICU length of stay (9.08 vs. 10.07 days, p < 0.01) and total hospitalization (14.64 vs. 16.63 days, p = 0.001). …”
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15930
Data Sheet 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.pdf...
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”
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15931
Image_1_v1_Case Report: J-Shaped External Fixator for Treatment of Mayo Type II Olecranon Fractures – A Novel Surgical Technique and Report of Clinical Applications.tif
Published 2022“…Purpose<p>We designed a J-shaped external fixator (J-EF) to provide a minimally invasive, one-step surgical method for olecranon fractures. …”
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15932
Temporal trends of antithrombotic therapy for stroke prevention in Korean patients with non-valvular atrial fibrillation in the era of non-vitamin K antagonist oral anticoagulants:...
Published 2017“…A substantial proportion (approx. 50%) of Korean patients with AF still remain undertreated.…”
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15933
Treatment consequence and adverse events of cyclin-dependent kinase 4/6 inhibitors on patients with hormone receptor-positive, HER2-negative metastatic breast cancer: a systematic...
Published 2025“…</p> <p>Eleven clinical trials published between 2015 and 2022 were included in our meta-analysis, with a total of 5572 eligible patients. This meta-analysis found that HR(+)/HER2(−) metastatic breast cancer treated with CDK4/6 inhibitors plus endocrine therapy can significantly improve progression-free survival(PFS) (HR: 0.55; <i>p</i> < 0.001), overall survival (OS) (HR: 0.79; <i>p</i> < 0.001), objective response rate (RR = 1.50; <i>p</i> < 0.001), clinical benefit rate (RR = 1.18; <i>p</i> < 0.001) and decrease progressive disease rate (RR = 0.49; <i>p</i> < 0.001). …”
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15934
Data_Sheet_1_Evaluation of the E-Mental Health Mindfulness-Based and Skills-Based “CoPE It” Intervention to Reduce Psychological Distress in Times of COVID-19: Results of a Bicentr...
Published 2021“…Secondary outcomes: There was a significant decrease in depressive symptoms and generalized anxiety, and a significant increase in self-efficacy and mindfulness between baseline (T0) and post-intervention (T1). …”
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15935
Functional Characterization of a Novel Outer Membrane Porin <em>KpnO</em>, Regulated by PhoBR Two-Component System in <em>Klebsiella pneumoniae</em> NTUH-K2044
Published 2012“…To dissect the role of PhoBR signaling system in regulating the expression of the <em>kpnO</em>, a <em>phoB</em><sup>KP</sup> isogenic mutant was constructed. …”
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15936
Preparation, X-ray Structure, and Reactivity of an Osmium-Hydroxo Complex Stabilized by an N-Heterocyclic Carbene Ligand: A Base-Free Catalytic Precursor for Hydrogen Transfer from...
Published 2008“…Complex <b>3</b> is also obtained in a two-step procedure involving the reaction of <b>2</b> with NaBH<sub>4</sub> to give (η<sup>6</sup>-<i>p</i>-cymene)OsH<sub>2</sub>(IPr) (<b>4</b>) and the protonation of the latter with HOTf. …”
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15937
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15938
Data Sheet 1_Identification of sepsis biomarkers through glutamine metabolism-mediated immune regulation: a comprehensive analysis employing mendelian randomization, multi-omics in...
Published 2025“…</p>Conclusion<p>SSC-A on HLA-DR + NK cells reduced the risk of sepsis by decreasing glutamine degradation. …”
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15939
Image_2_Genome-Wide Expression Analysis of Glyoxalase I Genes Under Hyperosmotic Stress and Existence of a Stress-Responsive Mitochondrial Glyoxalase I Activity in Durum Wheat (Tri...
Published 2022“…Accordingly, in the same tissues, hyperosmotic stress induced an increase (up to about 40%) of both GLYI activity and MG content as well as a decrease of GSH (up to about –60%) and an increase of GSSG content (up to about 7-fold) with a consequent strong decrease of the GSH/GSSG ratio (up to about –95%). …”
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15940
Table_1_Genome-Wide Expression Analysis of Glyoxalase I Genes Under Hyperosmotic Stress and Existence of a Stress-Responsive Mitochondrial Glyoxalase I Activity in Durum Wheat (Tri...
Published 2022“…Accordingly, in the same tissues, hyperosmotic stress induced an increase (up to about 40%) of both GLYI activity and MG content as well as a decrease of GSH (up to about –60%) and an increase of GSSG content (up to about 7-fold) with a consequent strong decrease of the GSH/GSSG ratio (up to about –95%). …”