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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
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17921
Response kinetics and relationship to Weber’s law in the m8 controller (Fig 10).
Published 2023“…<p>The set-point of <i>A</i> is <i>A</i><sub><i>set</i></sub>=3.0. (a) Step-wise increase of <i>k</i><sub>1</sub> from 1.0 to 5.0 at time <i>t</i>=100 at different and constant background perturbations <i>k</i><sub>3</sub> (0–80). …”
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17922
The immune control exerted by lytic and non-lytic CD8+ T cell responses.
Published 2013“…Here we show the results for the non-lytic control that blocks viral infection, similar results were found for non-lytic control that blocks viral production (Figures S6, S7 in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003656#ppat.1003656.s001" target="_blank">Text S1</a> and data not shown). …”
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17923
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17924
Data_Sheet_1_Evaluation of Brain Death in Laying Hens During On-Farm Killing by Cervical Dislocation Methods or Pentobarbital Sodium Injection.docx
Published 2019“…Within 15 s after administration of pentobarbital sodium, there were significant decreases in mean frequency bands, increases in mean F50 and F95, and decreases in Ptot, suggesting brain death. …”
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17925
Data_Sheet_1_Effect of epidural spinal cord stimulation on female sexual function after spinal cord injury.docx
Published 2023“…Sexual distress was reduced by 55%, with a mean decrease of 12 points (55.4%) from baseline (21.7 ± 17.2) to post-intervention (9.7 ± 10.8). …”
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17926
Table_1_Baseline mitochondrial DNA copy number and heart failure incidence and its role in overall and heart failure mortality in middle-aged women.pdf
Published 2022“…Baseline levels of mtDNA-CN were quantified by droplet digital PCR in a population-based follow-up study of middle-aged (50–59 years) Swedish women (n = 2,508). …”
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17927
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17928
Image_6_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF
Published 2019“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC<sub>50</sub> = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”
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17929
Image_4_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF
Published 2019“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC<sub>50</sub> = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”
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17930
Image_1_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF
Published 2019“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC<sub>50</sub> = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”
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17931
Image_5_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF
Published 2019“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC<sub>50</sub> = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”
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17932
Image_2_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF
Published 2019“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC<sub>50</sub> = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”
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17933
Image_3_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF
Published 2019“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC<sub>50</sub> = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”
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17934
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17935
PLK2i treatment of OHSCs does not affect generation of pS129 positive aggregates, but reduces the nuclear pS129 intensity.
Published 2021“…Scale bars = 20 μm. b) Quantification of the amount of aggregation (aggregate area normalized to tissue area), defined by MJF-14 staining (p-value = 0.09). c-d) Quantification of the mean fluorescence intensity of α-syn aggregates detected with MJF-14 (c, p-value = 0.712) and aggregate-specific pS129 that overlaps with MJF-14 (d, p-value = 0.214). e) Quantification of nuclear (non-aggregate related) pS129, illustrating a significant decrease in mean fluorescence intensity following PLK2i-treatment (p-value = 0.0087). f) Relative ratio of aggregate-specific pS129/nuclear pS129 in PFF-injected slices shows an increase of ratio of the signals of aggregates/background following PLK2i treatment, due to reduction of the non-aggregate-related nuclear pS129-signal (p-value = 0.009). …”
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17936
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates
Published 2021“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”
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17937
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates
Published 2021“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”
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17938
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates
Published 2021“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”
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17939
Genetic evaluation of growth in Polled Nellore via multi-trait models
Published 2018“…Unlikely, a decrease was observed from W205 to W365 for the maternal permanent environmental effect. …”
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17940
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates
Published 2021“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”