Let-7b targets at TLR4 and regulates TLR4 expression via post-transcriptional suppression. by Gui-gen Teng (380044)

“…A dose-dependent decrease of TLR4 protein was determined with let-7b mimics treatment. …”

Image_1_Cardiac resynchronization therapy in heart failure patients by using left bundle branch pacing.TIF by Ying Gu (203149)

“…</p>Results<p>Left bundle branch pacing was successful in all 34 patients (mean age 65.6 ± 11.2 years, 67.6% men). A significant decrease in QRS duration (QRSd) was observed after the LBBP operation for 1 month (153.2 ± 1.7 vs. 111.9 ± 2.6 ms, p < 0.01). …”

Table_1_Exogenous γ-aminobutyric acid (GABA) mitigated salinity-induced impairments in mungbean plants by regulating their nitrogen metabolism and antioxidant potential.docx by Abd Ullah (6529958)

“…In leaves, salinity caused a significant increase in Na+ concentration but a decrease inK+ concentration, resulting in a low K+/Na+ concentration (51- and 71% under 50- and 100- mMstress). …”

Table_1_Exogenous γ-aminobutyric acid (GABA) mitigated salinity-induced impairments in mungbean plants by regulating their nitrogen metabolism and antioxidant potential.docx by Abd Ullah (6529958)

“…In leaves, salinity caused a significant increase in Na+ concentration but a decrease inK+ concentration, resulting in a low K+/Na+ concentration (51- and 71% under 50- and 100- mMstress). …”

Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1 by Jernej Zorman (3146430)

“…<div><p>Shikonin is a highly lipophilic naphtoquinone found in the roots of <i>Lithospermum erythrorhizon</i> used for its pleiotropic effects in traditional Chinese medicine. …”

datasheet1_COVID-19 Incidence in Patients With Immunomediated Inflammatory Diseases: Influence of Immunosuppressant Treatments.docx by Natalia Soldevila-Domenech (9903768)

“…Our results report a decreased incidence of COVID-19 in patients receiving specific DMARDs with different immunodepressor mechanisms with striking sex differences. …”

DataSheet1_Antisense targeting of FOXP3+ Tregs to boost anti-tumor immunity.docx by Tatiana Akimova (345316)

“…Isolated human Treg, incubated with ASO FOXP3 for 3.5 hours, had significantly impaired suppressive function (66.4%) versus Scramble control. In murine studies, we observed a significant inhibition of tumor growth, while 13.6% (MC38) to 22% (TC1) of tumors were completely resorbed, in conjunction with ~50% decrease of Foxp3 mRNA by qPCR and decreased numbers of intratumoral Tregs. …”

C/EBPβ-Thr217 Phosphorylation Signaling Contributes to the Development of Lung Injury and Fibrosis in Mice by Martina Buck (82941)

DataSheet_1_Non-steroidal anti-inflammatory drugs and clinical outcomes in patients with COVID-19.docx by Jing Zhang (23775)

AS101 attenuates high glucose induced mesangial cell proliferation. by Itay Israel Shemesh (669254)

“…OD levels were compared to control which was normalized to 100%. Results represent mean±SEM from three experiments. #p<0.05 decrease vs. …”

Nilotinib inhibits cell viability and neurosphere formation in medulloblastoma cells (MB-PDX and DAOY). by Kirti Kandhwal Chahal (7411091)

“…Nilotinib was observed to be most potent in inhibiting the formation of NS from single cells. (<b>f)</b> A representative Western blot for quantitation of nuclear Gli-1 in MB-PDX and DAOY cells shows a decrease in Gli-1 protein after treatment with 5 μM Nilotinib for 24 hours. …”

ErbB signaling is implicated in generation of neurons and mitoses in the sub-ventricular zone. by Tomomi Sato (301255)

“…Impaired neurogenesis and a decrease in pH3-positive mitotic cells in the SVZ of AG1478-treated Tg(<i>pou4f1-hsp70l</i>:<i>GFP;-8</i>.…”

Table_1_Morphological characterization, pathogenicity screening, and molecular identification of Fusarium spp. isolates causing post-flowering stalk rot in maize.DOCX by J. Harish (14950603)

“…Pathogenicity test during the Kharif season showed 12 isolates with virulent disease symptoms with a mean severity ranging between 50 to 67 percent disease index (PDI) whereas in Rabi season, only five isolates were considered virulent, and the mean severity ranged between 52 to 67 PDI. …”

Maternal Nutrient Restriction Alters Ca²⁺ Handling Properties and Contractile Function of Isolated Left Ventricle Bundles in Male But Not Female Juvenile Rats by Thomas J. Harvey (800460)

“…Furthermore, male NR offspring showed a reduction in rate of rise of the caffeine-induced Ca²⁺ force response and a decrease in the protein content of ryanodine receptor (RYR2). …”

Image_1_Impact of ebb-delta dynamics on shoreline evolution along inlet-interrupted coasts.jpeg by Janaka Bamunawala (9775058)

“…As a result, the ebb-delta effect decreases the up-drift shoreline retreat by up to 37% and 48% at Thu Bon and Mawddach estuaries, respectively, while it reduces shoreline progradation of the down-drift coast of Mawddach estuary by up to ~50%. …”

Image_2_Impact of ebb-delta dynamics on shoreline evolution along inlet-interrupted coasts.jpeg by Janaka Bamunawala (9775058)

“…As a result, the ebb-delta effect decreases the up-drift shoreline retreat by up to 37% and 48% at Thu Bon and Mawddach estuaries, respectively, while it reduces shoreline progradation of the down-drift coast of Mawddach estuary by up to ~50%. …”

Image_3_Galantamine ameliorates hyperoxia-induced brain injury in neonatal mice.TIF by Nahla Zaghloul (636747)

Data_Sheet_1_Acute myocardial infarction induces remodeling of the murine superior cervical ganglia and the carotid body.docx by Yang Ge (667681)

DataSheet_1_Biophysical contexture of coastal biofilm-sediments varies heterogeneously and seasonally at the centimeter scale across the bed-water interface.docx by Xindi Chen (6485522)

“…Interestingly, the stratification of biological and physical properties followed a fixed relationship, where with the decrease of the grain size D₅₀, the EPS content increased exponentially, and this relationship was independent of temporal or spatial variation. …”

Data Sheet 1_The role of intestinal homeostasis in sevoflurane-induced myelin development and cognitive impairment in neonatal mice.docx by Chang Liu (35901)