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point decrease » point increase (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
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8741
Enhanced Rice Blast Resistance by CRISPR/Cas9-Targeted Mutagenesis of the ERF Transcription Factor Gene <i>OsERF922</i>
Published 2016“…In recent years, sequence-specific nucleases (SSNs) have been demonstrated to be powerful tools for the improvement of crops via gene-specific genome editing, and CRISPR/Cas9 is thought to be the most effective SSN. Here, we report the improvement of rice blast resistance by engineering a CRISPR/Cas9 SSN (C-ERF922) targeting the <i>OsERF922</i> gene in rice. …”
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8742
Simulated demonstration of apparent clustering arising from over-counting individual labeled molecules with a finite effective PSF.
Published 2012“…(E) Modified Ripley's functions, (L(r)−r)/r, calculated from clustered red centers is slightly lower than but resembles functions calculated for red signals at large r. …”
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8743
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8744
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8745
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8746
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8747
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8748
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8749
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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8750
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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8751
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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8752
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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8753
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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8754
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8755
PRISMA flow diagram.
Published 2024“…Lower sensitivity was attributed to absence of symptoms, errors in test conduct and absence of supervision or a digital support. We found no difference in COVIDST sensitivity between delta and omicron pre-dominant period. …”
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8756
FLIM-FRET measurements with KIRIN1 sensor detects relative changes in intracellular K<sup>+</sup>.
Published 2024“…For cell patch clamping and FLIM measurements, each data point represents 1 cell (A, B, C). For fish embryo FLIM imaging, we measured 2 or 3 locations in each tissue of 1 fin bud per embryo. …”
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8757
<i>NAB3</i> reduces the level of <i>IMD2</i> CUT terminator readthrough product from a reporter and native <i>IMD2</i> CUT and readthrough RNA, but <i>NAB3</i> does not significant...
Published 2015“…Samples of cells just after addition of galactose (0 hour time point) were also analyzed. Different immunoblots are outlined by black boxes. …”
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8758
An Allosteric Modulator of RNA Binding Targeting the N‑Terminal Domain of TDP-43 Yields Neuroprotective Properties
Published 2020“…<i>In silico</i> docking of 50K compounds to the NTD domain of TDP-43 identified a small molecule (nTRD22) that is bound to the N-terminal domain. …”
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8759
Meta-analyses of COVIDST diagnostic accuracy.
Published 2024“…Lower sensitivity was attributed to absence of symptoms, errors in test conduct and absence of supervision or a digital support. We found no difference in COVIDST sensitivity between delta and omicron pre-dominant period. …”
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8760