Showing 8,761 - 8,780 results of 32,731 for search '(( 50 ((we decrease) OR (((mean decrease) OR (a decrease)))) ) OR ( e point decrease ))', query time: 1.41s Refine Results
  1. 8761
  2. 8762
  3. 8763

    Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks by Sofia Benfeito (4345591)

    Published 2023
    “…Although the lipophilic triphenylphosphonium (TPP<sup>+</sup>) cation is widely used to target antioxidants to mitochondria, TPP<sup>+</sup>-based derivatives have shown cytotoxicity in several biological <i>in vitro</i> models. We confirmed that <b>Mito.TPP</b> is cytotoxic to both human neuronal (SH-SY5Y) and hepatic (HepG2) cells, decreasing intracellular adenosine triphosphate (ATP) levels, leading to mitochondrial membrane depolarization and reduced mitochondrial mass after 24 h. …”
  4. 8764
  5. 8765
  6. 8766
  7. 8767
  8. 8768
  9. 8769

    Image_1_Novel Action Targets of Natural Product Gliotoxin in Photosynthetic Apparatus.tif by Yanjing Guo (720645)

    Published 2020
    “…GT decreases the rate of oxygen evolution of PSII with an I<sub>50</sub> value of 60 µM. …”
  10. 8770

    Image_1_Novel Action Targets of Natural Product Gliotoxin in Photosynthetic Apparatus.tif by Yanjing Guo (720645)

    Published 2020
    “…GT decreases the rate of oxygen evolution of PSII with an I<sub>50</sub> value of 60 µM. …”
  11. 8771
  12. 8772
  13. 8773
  14. 8774
  15. 8775

    IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and <i>in vivo</i> half-life: Potential application in combination with broad neutralizing antibodi... by Wenwen Bi (8086730)

    Published 2019
    “…To overcome this limitation, we developed a new strategy to extend the <i>in vivo</i> half-life of a short HIV-1 fusion inhibitory peptide, CP24, by fusing it with the human IgG Fc-binding peptide (IBP). …”
  16. 8776

    New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome <i>bc1</i> in <i>Mycobacterium tuberculosis</i> by Andréanne Lupien (8351469)

    Published 2020
    “…Further analysis of the mode of action <i>in vitro</i> revealed that 11626252 exposure leads to ATP depletion, a decrease in the oxygen consumption rate and also overexpression of the cytochrome <i>bd</i> oxidase in <i>M</i>. …”
  17. 8777
  18. 8778

    Genetic Polymorphism of Cytochrome P450 4F2, Vitamin E Level and Histological Response in Adults and Children with Nonalcoholic Fatty Liver Disease Who Participated in PIVENS and T... by Shaminie Athinarayanan (554806)

    Published 2014
    “…Among those receiving Vit E treatment, CYP4F2 V433M genotype was associated with significantly decreased plasma α-tocopherol levels at w48 (p = 0.003 for PIVENS and p = 0.026 for TONIC) but not at w96. …”
  19. 8779

    Sex Differences in the Quality of Diabetes Care in the Netherlands (ZODIAC-45) by Steven H. Hendriks (841320)

    Published 2016
    “…In patients ≥75 years it decreased from 72% to 50% in men and 85% to 56% in women. …”
  20. 8780

    Representative cases. by Andrey Zhivov (288542)

    Published 2015
    “…Case 2: 62-year-old female patient, DM duration 7 years, HbA<sub>1c</sub> 9.4%, NDS 5 points; Wagner 2 (d), advanced non-proliferative DR (e), moderate decrease in confocal SBP parameters (NFD = 0.010 μm/μm<sup>2</sup>) (f). …”