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point decrease » point increase (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
e point » _ point (Expand Search), 5 point (Expand Search), a point (Expand Search)
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8761
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8762
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8763
Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks
Published 2023“…Although the lipophilic triphenylphosphonium (TPP<sup>+</sup>) cation is widely used to target antioxidants to mitochondria, TPP<sup>+</sup>-based derivatives have shown cytotoxicity in several biological <i>in vitro</i> models. We confirmed that <b>Mito.TPP</b> is cytotoxic to both human neuronal (SH-SY5Y) and hepatic (HepG2) cells, decreasing intracellular adenosine triphosphate (ATP) levels, leading to mitochondrial membrane depolarization and reduced mitochondrial mass after 24 h. …”
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8764
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8765
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8766
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8767
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8768
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8769
Image_1_Novel Action Targets of Natural Product Gliotoxin in Photosynthetic Apparatus.tif
Published 2020“…GT decreases the rate of oxygen evolution of PSII with an I<sub>50</sub> value of 60 µM. …”
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8770
Image_1_Novel Action Targets of Natural Product Gliotoxin in Photosynthetic Apparatus.tif
Published 2020“…GT decreases the rate of oxygen evolution of PSII with an I<sub>50</sub> value of 60 µM. …”
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8771
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8772
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8773
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8774
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8775
IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and <i>in vivo</i> half-life: Potential application in combination with broad neutralizing antibodi...
Published 2019“…To overcome this limitation, we developed a new strategy to extend the <i>in vivo</i> half-life of a short HIV-1 fusion inhibitory peptide, CP24, by fusing it with the human IgG Fc-binding peptide (IBP). …”
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8776
New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome <i>bc1</i> in <i>Mycobacterium tuberculosis</i>
Published 2020“…Further analysis of the mode of action <i>in vitro</i> revealed that 11626252 exposure leads to ATP depletion, a decrease in the oxygen consumption rate and also overexpression of the cytochrome <i>bd</i> oxidase in <i>M</i>. …”
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8777
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8778
Genetic Polymorphism of Cytochrome P450 4F2, Vitamin E Level and Histological Response in Adults and Children with Nonalcoholic Fatty Liver Disease Who Participated in PIVENS and T...
Published 2014“…Among those receiving Vit E treatment, CYP4F2 V433M genotype was associated with significantly decreased plasma α-tocopherol levels at w48 (p = 0.003 for PIVENS and p = 0.026 for TONIC) but not at w96. …”
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8779
Sex Differences in the Quality of Diabetes Care in the Netherlands (ZODIAC-45)
Published 2016“…In patients ≥75 years it decreased from 72% to 50% in men and 85% to 56% in women. …”
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8780
Representative cases.
Published 2015“…Case 2: 62-year-old female patient, DM duration 7 years, HbA<sub>1c</sub> 9.4%, NDS 5 points; Wagner 2 (d), advanced non-proliferative DR (e), moderate decrease in confocal SBP parameters (NFD = 0.010 μm/μm<sup>2</sup>) (f). …”