cFLIP partially regulates extrinsic apoptosis in human macrophages following IKK blockade. by Neha M. Nataraj (19485995)

The 3-D QSAR/CoMFA color contour maps for COX I (A) and COX II (B). by Pan Wang (198097)

DataSheet_1_Continuous response despite reduced dose of trametinib as single agent in an adolescent with a relapsed disseminated pediatric low-grade glioma KIAA1549-BRAF fusion pos... by Serafin Castellano-Damaso (18601609)

“…There is not much information in the literature regarding whether reducing the dose of trametinib is able to maintain efficacy while, at the same time, decreasing toxicity. Here, we present an adolescent, with severe skin toxicity, whose trametinib dose was reduced by 50% and efficacy on the tumor continued while skin toxicity significantly decreased.…”

Image 1_Distinct brain and neurocognitive transformations after bariatric surgery: a pilot study.jpeg by Bhaswati Roy (2802559)

“…Surgery induced further gray matter volume and brain tissue changes along with reduced cognitive scores within the immediate postoperative period (MoCA 26 vs 24, P < 0.001). At six months, we observed reversal of brain alterations for most patients and a concomitant rebound of cognitive scores to patient’s baseline status.…”

Image_1_Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis.pdf by Iddo Vardi (9343361)

“…Next-generation sequencing of the TCRB and IgH was performed for global immune repertoire analysis of circulating lymphocytes.</p><p>Results: We identified a novel deleterious c.1455C>A (p.Y485X) mutation in LRBA. …”

Table_2_Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis.XLSX by Iddo Vardi (9343361)

“…Next-generation sequencing of the TCRB and IgH was performed for global immune repertoire analysis of circulating lymphocytes.</p><p>Results: We identified a novel deleterious c.1455C>A (p.Y485X) mutation in LRBA. …”

Table_3_Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis.XLSX by Iddo Vardi (9343361)

“…Next-generation sequencing of the TCRB and IgH was performed for global immune repertoire analysis of circulating lymphocytes.</p><p>Results: We identified a novel deleterious c.1455C>A (p.Y485X) mutation in LRBA. …”

Table_1_Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis.XLSX by Iddo Vardi (9343361)

“…Next-generation sequencing of the TCRB and IgH was performed for global immune repertoire analysis of circulating lymphocytes.</p><p>Results: We identified a novel deleterious c.1455C>A (p.Y485X) mutation in LRBA. …”

Behavior effects after LABP acute exposure. by Kassia Martins Fernandes Pereira (12219197)

“…Asterisks indicate statistical differences between groups (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001). n = 24/group a-20 min; 28/group b-20 min; 28/group c-25 min; 50/group d-60 min.…”

DDX5 and DDX17 are required for KSHV lytic reactivation in BCBL1 cells and primary infection in endothelial cells. by Praneet Kaur Sandhu (21156149)

HIFN reduces retinal and visual function deficits following ocular trauma. by Shweta Modgil (12864344)

“…HIFN rescued visual acuity and contrast sensitivity deficit at all the time points. At 7 weeks, visual function is better in HIFN-treated animals compared to HIOC. …”

Increased sediment load during a large-scale dam removal changes nearshore subtidal communities by Stephen P. Rubin (4672648)

“…Macroalgae, predominantly kelp and foliose red algae, were abundant before dam removal with combined cover levels greater than 50%. Where persistent sediment deposits formed, macroalgae decreased greatly or were eliminated. …”

TLR3 deficiency promoted the activation of TGF-β1/Smad2/3 pathway and myofibroblast caused by <i>C</i>. by Yuru Wang (846969)

Supplementary Material for: Should Colorectal Cancer Screening in Portugal Start at the Age of 45 Years? A Cost-Utility Analysis by Currais P. (10117210)

“…<b><i>Results:</i></b> In Portugal, in 1993–2010, there was an increase in CRC incidence of 17% (from 25 to 30/100,000), 35% (from 39 to 54/100,000), and 71% (from 52 to 97/100,000) in patients aged 45–49 years, 50–54 years, and 55–59 years, respectively. The mortality rate of patients aged 45–54 years remained stable between 2003 and 2016 (12/100,000) as a counterpoint to a moderate decrease in those aged 55–64 years (from 38 to 35/100,000) and a sharp reduction in those aged 65–75 years (from 93 to 75/100,000). …”

Image_1_Hsa_circ_0000479 as a Novel Diagnostic Biomarker of Systemic Lupus Erythematosus.TIF by Gangqiang Guo (3278922)

“…Western blotting revealed that the expression of Wnt-16 protein was significantly decreased in SLE.</p><p>Conclusion: Our results suggest that hsa_circ_0000479 has potential as a novel biomarker for the diagnosis of SLE.…”

Image_2_Hsa_circ_0000479 as a Novel Diagnostic Biomarker of Systemic Lupus Erythematosus.TIF by Gangqiang Guo (3278922)

“…Western blotting revealed that the expression of Wnt-16 protein was significantly decreased in SLE.</p><p>Conclusion: Our results suggest that hsa_circ_0000479 has potential as a novel biomarker for the diagnosis of SLE.…”

Impaired bone formation in <i>Col1a1-Krm2</i> transgenic mice. by Jochen Schulze (365258)

“…<p>(A) Toluidine blue staining of non-decalcified vertebral body sections from 6 weeks old female wildtype and <i>Col1a1-Krm2</i> transgenic littermates revealing that the normal appearance of cuboidal osteoblasts (arrows) covering trabecular bone surfaces is only observed in wildtype controls (scale bars, 50 µm). …”

S1 Graphical abstract - by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”

The top 10 hub targets. by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”

Original images for blots and gels requirements. by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”