Image 5_Getah virus triggers ROS-mediated autophagy in mouse Leydig cells.jpg by Fengqin Li (126568)

“…When autophagy levels were reduced using NAC and 3-MA, a corresponding decrease in TCID₅₀ was observed. …”

<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation by jin guan (21792620)

“…Typhimurium, among which the <i>StiP</i> deletion strain (263<i>ΔStiP</i>) showed the greatest serum resistance reduction (2.49-fold). We further explored the role of <i>StiP</i> in host blood environment adaptation and found that 263<i>ΔStiP</i> displayed 3.12-fold reduced HeLa cell adhesion, 3.74-fold lower HeLa cell invasion, 1.92-fold decreased intra-macrophage survival, and 50% reduced serum resistance versus wild-type 263 (WT263), collectively indicating that <i>StiP</i> is critical for host blood environment adaptation in invasive <i>S</i>. …”

Boot unmounting procedure. by Giulio Masiero (9360878)

Effect of Flow Conditions on the Dynamics of Chemical Demulsification in Highly Viscous Emulsion Flow by Samuel Vitor Saraiva (17984521)

“…We evaluated the effects of flow rate (40–120 mL/min), dispersed phase fraction (30–50 vol %), temperature (30–50 °C), and shear promoted by a pump on the dynamics of demulsification model parameters. …”

DataSheet1_Investigations of potential non-amino acid SNAT2 inhibitors.docx by Sebastian Jakobsen (17732745)

“…Here we have investigated the ability of MMTC and four other compounds selected from the screen by Gauthier-Coles et al. to decrease ³H-Gly uptake in hyperosmotically treated human prostate cancer PC-3 cells. …”

Experimental mutagenesis results. by Barry J. Grant (19471)

“…Mutant R326A shows a ∼2.5-fold increase in V_max for the microtubule-activated ATPase, with a ∼4-fold higher K_m. …”

Supplementary file 1_Microbial cross contamination in household laundering and microbial ecology of household washing machines.pdf by Kelly Whitehead (22449349)

“…Front-load machines had significantly higher microbial loads than top-load machines (average bacterial counts: 6.50 ± 2.46 Log10/swab vs. 3.79 ± 1.73 Log10/swab). …”

DataSheet1_Inactivation influences the extent of inhibition of voltage-gated Ca+2 channels by Gem—implications for channelopathies.pdf by Salma Allam (16836396)

“…Using titrated levels of Gem expression in Xenopus oocytes to inhibit WT P/Q-type calcium channels by ∼50%, we show that inhibition is dependent on channel inactivation. …”

Data_Sheet_1_Cell-Free Fermentation Broth of Bacillus velezensis Strain S3-1 Improves Pak Choi Nutritional Quality and Changes the Bacterial Community Structure of the Rhizosphere... by Kaiheng Lu (9359012)

“…Based on high-throughput sequencing data, our analysis of soil microbial communities used R, NETWORK, and PICRUSt showed that the CFB treatment can enhance the relative abundance of Acidobacteria in the soil, decrease the abundance of native Bacillus in the soil, change the microbial community structure of the top 50 operational taxonomic units (OTUs), and improve soil microbial carbon metabolism and nitrogen metabolism. …”

Selleck library antibiotic activities. by Jennifer M. Colquhoun (499820)

“…<p>¹ X indicates growth inhibitory phenotype in the indicated screening condition, measured as no visible growth in Mueller-Hinton (MH) or serum; ≥ 2-log decrease in colony forming units in lung surfactant; ≥ 2-fold increase in adenylate kinase signal in comparison to DMSO treated biofilms.…”

Selleck library non-antibiotic activities. by Jennifer M. Colquhoun (499820)

“…<p>¹ X indicates growth inhibitory phenotype in the indicated screening condition, measured as no visible growth in Mueller-Hinton (MH) or serum; ≥ 2-log decrease in colony forming units in lung surfactant; ≥ 2-fold increase in adenylate kinase signal in comparison to DMSO treated biofilms.…”

CCDC66-depleted cells exhibit abnormal ciliary signaling and transport. by Jovana Deretic (13113617)

“…Super plot of normalized individual experimental values with mean ± SEM represents 3 independent experiments. <i>n</i> > 50 cells for each condition. Mean ciliary fluorescence density of BBS4 in CCDC66 depletion is decreased to 0.208-fold of the control mean. …”

DataSheet3_Fidelity of a Bacterial DNA Polymerase in Microgravity, a Model for Human Health in Space.pdf by Aaron H Rosenstein (11763995)

“…In microgravity Klenow exonuclease+ showed a median 1.1-fold per-base decrease in polymerization fidelity for base substitutions when compared to earth-like gravity (p = 0.02), but in the absence of proofreading activity, a 2.4-fold decrease was observed (p = 1.98 × 10⁻¹¹). …”

DataSheet1_Fidelity of a Bacterial DNA Polymerase in Microgravity, a Model for Human Health in Space.PDF by Aaron H Rosenstein (11763995)

“…In microgravity Klenow exonuclease+ showed a median 1.1-fold per-base decrease in polymerization fidelity for base substitutions when compared to earth-like gravity (p = 0.02), but in the absence of proofreading activity, a 2.4-fold decrease was observed (p = 1.98 × 10⁻¹¹). …”

miR-27b regulates ASC-mediated suppression of CFSE-labeled allogeneic CD4⁺ T cell proliferation. by Kuang-Den Chen (322973)

An Integrated Disease/Pharmacokinetic/Pharmacodynamic Model Suggests Improved Interleukin-21 Regimens Validated Prospectively for Mouse Solid Cancers by Moran Elishmereni (203218)

“…Simulations of the verified model surfaced important therapeutic insights: (1) Fractionating the standard daily regimen (50 µg/dose) into a twice daily schedule (25 µg/dose) is advantageous, yielding a significantly lower tumor mass (45% decrease); (2) A low-dose (12 µg/day) regimen exerts a response similar to that obtained under the 50 µg/day treatment, suggestive of an equally efficacious dose with potentially reduced toxicity. …”

<b>Genome assembly at chromosome level and evolutionary analysis of </b><i><b>Coregonus ussurinsis</b></i><b> Berg</b> by Tianqing Huang (9743483)

“…The sequence length was 2,627.19 Mb with a contig N50 length of 4.27 Mb. Then 3,109 contigs were assembled into scaffolds, resulting in a genome assembly with 40 chromosomes and a scaffold N50 length of 62.20 Mb, and the size of the genome was 2.51 Gb, and the integrity was more than 95% by BUSCO test. …”

Warfarin pretreatment enhances tumor Ad5ROBO4 vector expression. by Zhi Hong Lu (389413)

“…Warfarin pretreatment produced a 2.5-fold increased splenic and a 3-fold decreased liver expression while all other organs still evidenced trace to undetectable expression. …”

Comparison of normalization methods. by Mikhail G. Dozmorov (242442)

“…A) Sensitivity and B) Precision (Y axes) for symmetrical changes in gene expression (2-fold increase in 10% and 2-fold decrease in another 10% of data). …”

Data_Sheet_1_Microbial Interactions With Dissolved Organic Matter Drive Carbon Dynamics and Community Succession.docx by Xiaoqin Wu (470428)

“…In this study, we fed sediment-derived dissolved organic matter (DOM) to groundwater microbes and continually analyzed microbial transformation of DOM over a 50-day incubation. …”