Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy by Maude Giroud (2017114)

“…When tested in vivo, compound <b>7</b> showed efficacy after oral dosing in a mouse model of peripheral nerve injury by decreasing plasma neurofilament light (NfL) levels at 50 mg/kg compared with vehicle-treated control mice, holding promise for the treatment of neurodegenerative and neurological disorders.…”

Mechanics that yield pressure compensating behavior and a linear increase in the total loss coefficient. by Pulkit Shamshery (3911029)

Exploitation-exploration parameter β₁ and γ influence specific aspects of task performance. by Kim T. Blackwell (10915047)

“…</b> Total reward has very low sensitivity to minimum and maximum value of β₁. Using a constant value of β₁ neither increases nor decreases total reward (F(4,394) = 2.52, P = 0.113). …”

Cycle threshold values at which a specific number of dogs out of 11 dogs was able to detect SARS-CoV-2 in samples from Merida, Yucatán, México. by Víctor M. Vidal-Martínez (18707335)

Effect of DE of <i>S. malaccense</i> and <i>S. samarangense</i> leaves on A) ATP, B) p-mTOR, C) beclin-1, and D) p-AMPK levels. by Fatma A. Moharram (9276104)

Total ion chromatogram (TIC) obtained from HPLC-MS of the defatted aqueous methanol extract of <i>S. malaccense</i> leaves in (A) positive and (B) negative ionization modes. by Fatma A. Moharram (9276104)

Total ion chromatogram (TIC) obtained from HPLC-MS of the defatted aqueous methanol extract of <i>S. samarangense</i> leaves in (A) positive and (B) negative ionization modes. by Fatma A. Moharram (9276104)

Effect of different doses of the defatted extract (DE) of the leaves of <i>S. malaccense</i> and <i>S. samarangense</i> on urea and creatinine levels. Data represented as mean±SEM... by Fatma A. Moharram (9276104)

Effect of DE of <i>S. malaccense</i> and <i>S. samarangense</i> leaves on histopathological examination of the kidney tissues. by Fatma A. Moharram (9276104)

HPLC-MS tentative identification of phenolic metabolites from the defatted extract (DE) of <i>S. malaccense</i> (SM) and <i>S. samarangense</i> (SS) leaves. by Fatma A. Moharram (9276104)

Estimated total phenolic content (TPC), and total flavonoid content (TFC) in the defatted extract (DE) of <i>S. malaccense</i> and <i>S. samarangense</i> leaves. by Fatma A. Moharram (9276104)

Effect of DE of <i>S. malaccense</i> and <i>S. samarangense</i> on A) GSH, B) SOD, C) TNF-α, D) IL-1β, E) p-NF-κB, and F) Caspase-3 levels. by Fatma A. Moharram (9276104)

Effect of different doses (mg/Kg) of the defatted extract (DE) of the leaves of <i>S. malaccense</i> and <i>S. samarangense</i> on serum ALT and AST levels. Data represented as mea... by Fatma A. Moharram (9276104)

The light-induced decrease in frequency in <i>En1</i>-Arch cords is due to a ventral, nonglutamatergic mechanism and is similar in <i>En1</i>-Arch and <i>En1</i>-Arch-tdT spinal co... by Melanie Falgairolle (759132)

Table 1_Sex-specific association between body mass index and cerebral microbleed progression in adults aged 50–85 years.docx by Cindy W. Yoon (10146428)

“…We used a generalized linear mixed model with a negative binomial distribution to assess the association between BMI and the 2-year change in CMB count, and conducted sex-stratified analyses to account for potential sex-specific effects.…”

Tomato + broccoli in combination with PhIP results in a significant decrease in number and size of ventral prostate (VP) cribiform PIN/CIS lesions. by Kirstie Canene-Adams (365217)

Schematic diagram of the experimental setup: The single-use PEEP valves were consecutively attached to a mechanically driven self-inflating bag. by Julia C. Hartung (2512117)

Results for prediction accuracy. Number of census tracts that have the same and deviated observed and predicted category for term-based predictions (term 1: before March 31, 2021,... by Fatih Gezer (21485468)

DataSheet1_Assessing spatial and temporal changes in diversity of copepod crustaceans: a key step for biodiversity conservation in groundwater-fed springs.docx by Francesco Cerasoli (4574053)

Coalescence of a Ferrofluid Drop at Its Bulk Surface with or without a Magnetic Field by Qindan Zhang (7343165)