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Fig 2 -
Published 2024“…<p>In-hospital mortality rates across the quartiles for SI, DSI, MSI, and Age-SI values among patients with normal LVEF (≥ 50%; A, B, C, and D, respectively) and those with decreased LVEF (< 50%; E, F, G, and H, respectively). …”
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Table1_Apoptotic volume decrease (AVD) in A549 cells exposed to water-soluble fraction of particulate matter (PM10).DOCX
Published 2023“…This result suggests the role of oxidative stress in the PM<sub>10</sub> induction of AVD as one of the first steps in cytotoxicity.</p>…”
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Flow chart for the enrolled patients.
Published 2024“…Left ventricular (LV) function was categorized as either normal LV ejection fraction (LVEF ≥ 50%) or decreased LVEF (<50%).</p><p>Results</p><p>Among the 1,194 patients with septic shock, 392 (32.8%) who underwent echocardiography within 24 h of time zero were included in the final analysis (normal LVEF: n = 246; decreased LVEF: n = 146). …”
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Decreased capillary density and cardiac fibrosis in <i>Nkx2.5-Cre/Foxm1<sup>fl/fl</sup></i> heart.
Published 2013“…Scale bars represent 100 µm in A–F and 50 µm in G–H.</p>…”
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A 27-year-old female with an acute cardioembolic infarction fifteen hours after the onset.
Published 2020“…<b>G:</b> MTR<sub>asym</sub> spectra show decreased MTR<sub>asym</sub>(3.5ppm) or APTW signal (%) in the infarct area compared to the CNAWM. mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; FLAIR, fluid attenuated inversion recovery; DWI, diffusion-weighted imaging; ROI, region-of-interest; ADC, apparent diffusion coefficient; APTW, amide proton transfer-weighted; CEST, chemical exchange saturation transfer; CNAWM, contralateral normal-appearing white matter; S<sub>sat</sub>(ppm) and S<sub>0</sub>, the signal intensities obtained with and without selective radiofrequency saturation pulse irradiation, respectively; APT<sub>10</sub>, APT<sub>25</sub>, APT<sub>50</sub>, APT<sub>75</sub>, and APT<sub>90</sub>, correspond to the 10th, 25th, 50th, 75th, and 90th percentiles of APTW signal value, respectively.…”
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Structure–Activity Studies of 1<i>H</i>‑Imidazo[4,5‑<i>c</i>]quinolin-4-amine Derivatives as A<sub>3</sub> Adenosine Receptor Positive Allosteric Modulators
Published 2022“…Although having low Caco-2 permeability and high plasma protein binding, hydrophobic 2-cyclohept-4-enyl-<i>N</i>-3,4-dichlorophenyl, MRS7788 <b>18</b>, and 2-heptan-4-yl-<i>N</i>-4-iodophenyl, MRS8054 <b>39</b>, derivatives were orally bioavailable in rat. 2-Heptan-4-yl-<i>N</i>-3,4-dichlorophenyl <b>14</b> and 2-cyclononyl-<i>N</i>-3,4-dichlorophenyl <b>20</b> derivatives and <b>39</b> greatly enhanced Cl-IB-MECA-stimulated [<sup>35</sup>S]GTPγS binding <i>E</i><sub>max</sub>, with only <b>12b</b> trending toward decreasing the agonist EC<sub>50</sub>. A feasible route for radio-iodination at the <i>p-</i>position of a 4-phenylamino substituent suggests a potential radioligand for allosteric site binding. …”
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Structure–Activity Studies of 1<i>H</i>‑Imidazo[4,5‑<i>c</i>]quinolin-4-amine Derivatives as A<sub>3</sub> Adenosine Receptor Positive Allosteric Modulators
Published 2022“…Although having low Caco-2 permeability and high plasma protein binding, hydrophobic 2-cyclohept-4-enyl-<i>N</i>-3,4-dichlorophenyl, MRS7788 <b>18</b>, and 2-heptan-4-yl-<i>N</i>-4-iodophenyl, MRS8054 <b>39</b>, derivatives were orally bioavailable in rat. 2-Heptan-4-yl-<i>N</i>-3,4-dichlorophenyl <b>14</b> and 2-cyclononyl-<i>N</i>-3,4-dichlorophenyl <b>20</b> derivatives and <b>39</b> greatly enhanced Cl-IB-MECA-stimulated [<sup>35</sup>S]GTPγS binding <i>E</i><sub>max</sub>, with only <b>12b</b> trending toward decreasing the agonist EC<sub>50</sub>. A feasible route for radio-iodination at the <i>p-</i>position of a 4-phenylamino substituent suggests a potential radioligand for allosteric site binding. …”
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Table 1_Association of memory function with COVID-19 outcomes in adults aged 50 years and older: analysis of three prospective cohorts.docx
Published 2025“…The aORs for COVID-19 mortality were 1.06 (95% CI, 0.93–1.20) and 1.14 (95% CI, 1.01–1.28) per word decrease in immediate and delayed 10-words recall in SHARE, respectively. …”
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