Identification of Chalcones as <i>Fasciola hepatica</i> Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach by Florencia Ferraro (3146766)

“…One of the compounds, <b>C34</b>, tightly bounds to juvenile specific <i>Fh</i>CL3 with an IC₅₀ of 5.6 μM. We demonstrated that <b>C34</b> is a slow-reversible inhibitor that interacts with the Cys-His catalytic dyad and key S₂ and S₃ pocket residues, determinants of the substrate specificity of this family of cysteine proteases. …”

Interventions to improve antiretroviral therapy adherence among adolescents in low- and middle-income countries: A systematic review of the literature by Kathleen Ridgeway (4479478)

“…Moreover, HIV-related mortality increased by 50% between 2005 and 2012 for adolescents 10–19 years while it decreased by 30% for all other age groups. …”

Mitotic spindle defects and reduced RhoA activation in LCLs of index patients with <i>ARHGEF2</i> mutation. by Ethiraj Ravindran (790330)

Data Sheet 2_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…</p>Result<p>MR analysis indicated that glucosamine was associated with increased cognitive performance (p = 8.46E-04), FIS (p = 7.50E-04), ALM (p = 6.45E-08), WBFM (p = 1.97E-03), usual walking pace (p = 2.55E-07), and moderate to vigorous physical activity levels (p = 3.29E-03), but associated with decreased FA risk (p = 3.77E-05) and DNA methylation GrimAge acceleration (p = 0.001). …”

DataSheet_1_Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis.docx by Jun Tang (32983)

“…Reverse MR analysis was used to detect reverse causal relationships.</p>Results<p>We identified 23 causal links between specific gut microbiota taxa and SpA levels. …”

Table_1_Gut microbiota and type 1 diabetes: a two-sample bidirectional Mendelian randomization study.xlsx by Manjun Luo (8903549)

“…Objective<p>The real causal relationship between human gut microbiota and T1D remains unclear and difficult to establish. Herein, we adopted a two-sample bidirectional mendelian randomization (MR) study to evaluate the causality between gut microbiota and T1D.…”

Interplay between fungicides and parasites: Tebuconazole, but not copper, suppresses infection in a <i>Daphnia-Metschnikowia</i> experimental model by Ana P. Cuco (3775534)

“…Most importantly, while copper and parasite effects were mostly independent, tebuconazole suppressed infection. In a follow-up experiment, we tested the effect of a lower range of tebuconazole concentrations (0.00, 6.25, 12.5, 25.0, 50.0 and 100 μg L^-1) crossed with increasing parasite challenge (2 <i>Daphnia</i> clones × 6 contaminant concentrations × 2 parasite levels × 20 replicates = 480 experimental units). …”

Data Sheet 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…</p>Result<p>MR analysis indicated that glucosamine was associated with increased cognitive performance (p = 8.46E-04), FIS (p = 7.50E-04), ALM (p = 6.45E-08), WBFM (p = 1.97E-03), usual walking pace (p = 2.55E-07), and moderate to vigorous physical activity levels (p = 3.29E-03), but associated with decreased FA risk (p = 3.77E-05) and DNA methylation GrimAge acceleration (p = 0.001). …”

Vertically and Horizontally Drawing Formation of Graphite Pencil Electrodes on Paper by Frictional Sliding for a Disposable and Foldable Electronic Device by Junseo Kim (9920910)

“…Repetitive drawing in one-way direction reduced the roughness of the paper surface, decreasing the grain boundaries of graphite. This increases the electron pathway at the electrode, thus reducing the resistance to less than 50 Ω. …”

Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLD by Na Jiao (10056370)

“…NAFLD microbiota exhibited decreased diversity and microbial associations. We established a classifier model with 53 differential species exhibiting a robust diagnostic accuracy (AUC=0.97) for dectecting NAFLD. …”

Vertically and Horizontally Drawing Formation of Graphite Pencil Electrodes on Paper by Frictional Sliding for a Disposable and Foldable Electronic Device by Junseo Kim (9920910)

“…Repetitive drawing in one-way direction reduced the roughness of the paper surface, decreasing the grain boundaries of graphite. This increases the electron pathway at the electrode, thus reducing the resistance to less than 50 Ω. …”

Vertically and Horizontally Drawing Formation of Graphite Pencil Electrodes on Paper by Frictional Sliding for a Disposable and Foldable Electronic Device by Junseo Kim (9920910)

“…Repetitive drawing in one-way direction reduced the roughness of the paper surface, decreasing the grain boundaries of graphite. This increases the electron pathway at the electrode, thus reducing the resistance to less than 50 Ω. …”

<b>Living in a multi-stressor world: nitrate pollution and thermal stress interact to affect amphibian larvae</b> by Noa Sinai (17693221)

“…The metamorphic and physiological traits of amphibian larvae during the critical onset of metamorphosis are particularly susceptible to these stressors. We used a crossed experimental design subjecting <i>Rana temporaria </i>larvae to four constant rearing temperatures (18, 22, 26, 28 °C) crossed with three environmentally relevant nitrate concentrations (0, 50, 100 mg × L^-1) to investigate the interactive and individual effects of these stressors on metamorphic (i.e., growth and development) and physiological traits (i.e., metabolism and heat tolerance) at the onset of metamorphosis. …”

Vertically and Horizontally Drawing Formation of Graphite Pencil Electrodes on Paper by Frictional Sliding for a Disposable and Foldable Electronic Device by Junseo Kim (9920910)

“…Repetitive drawing in one-way direction reduced the roughness of the paper surface, decreasing the grain boundaries of graphite. This increases the electron pathway at the electrode, thus reducing the resistance to less than 50 Ω. …”

Vertically and Horizontally Drawing Formation of Graphite Pencil Electrodes on Paper by Frictional Sliding for a Disposable and Foldable Electronic Device by Junseo Kim (9920910)

“…Repetitive drawing in one-way direction reduced the roughness of the paper surface, decreasing the grain boundaries of graphite. This increases the electron pathway at the electrode, thus reducing the resistance to less than 50 Ω. …”

Vertically and Horizontally Drawing Formation of Graphite Pencil Electrodes on Paper by Frictional Sliding for a Disposable and Foldable Electronic Device by Junseo Kim (9920910)

“…Repetitive drawing in one-way direction reduced the roughness of the paper surface, decreasing the grain boundaries of graphite. This increases the electron pathway at the electrode, thus reducing the resistance to less than 50 Ω. …”

Vertically and Horizontally Drawing Formation of Graphite Pencil Electrodes on Paper by Frictional Sliding for a Disposable and Foldable Electronic Device by Junseo Kim (9920910)

“…Repetitive drawing in one-way direction reduced the roughness of the paper surface, decreasing the grain boundaries of graphite. This increases the electron pathway at the electrode, thus reducing the resistance to less than 50 Ω. …”

EFFECTS OF A NEW INTRAVENOUS ELECTROLYTE SOLUTION FOR USE IN VETERINARY PRACTICE ON THE ELECTROLYTE AND ACID-BASE BALANCES OF HEALTHY CATTLE by Priscilla Fajardo Valente Pereira (6138611)

“…Eight healthy adult, crossbred Bos taurus cattle received two treatments in a cross-over design: isotonic saline solution (IS) and test solution (TS) with 145 mEq of Na+, 5 mEq of K+, 4 mEq of Ca++, 2 mEq of Mg++, 96 mEq of Cl-, 60 mEq of lactate, 50 g of dextrose, and 4 mg of cyanocobalamin per liter. …”

Vertically and Horizontally Drawing Formation of Graphite Pencil Electrodes on Paper by Frictional Sliding for a Disposable and Foldable Electronic Device by Junseo Kim (9920910)

“…Repetitive drawing in one-way direction reduced the roughness of the paper surface, decreasing the grain boundaries of graphite. This increases the electron pathway at the electrode, thus reducing the resistance to less than 50 Ω. …”

Table 1_Case Report: Generalized anxiety disorder and hypertension: a bidirectional loop unraveled by integrated management.docx by Junming Chen (3603422)

“…</p>Case presentation<p>We report a 61-year-old male with 26-year refractory HTN and new-onset GAD triggered post-thyroidectomy. …”