Resveratrol induces senescence through activation of p53, p21^CIP1 and p16^INK4A. by Mehtap Kilic Eren (591048)

Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo by Zhiqiang Li (102723)

“…Treatment of such diseases with small-molecule NIK inhibitors is a reasonable but underexplored approach. In this paper, we reported the discovery of a potent and selective NIK inhibitor <b>46</b> (XT2). …”

Crz1 mediates masking in response to exogenous calcium. by Andrew S. Wagner (11331477)

Microscopic Study of Hydroxyapatite Dissolution As Affected by Fluoride Ions by Ki-Young Kwon (2190616)

“…In the presence of 10 mM NaF, individual surface step retraction velocities decreased by about a factor of 5 as compared to NaF-free conditions. …”

Variable Kinetic Isotope Effect Reveals a Multistep Pathway for Protonolysis of a Pt–Me Bond by Irving D. Rettig (14117340)

“…At lower concentrations of acid, the KIE decreased significantly (KIE = ∼6 for 0.1 mM (cod)PtMe₂ and 0.2 mM acid). …”

The functions <i>G</i>_<i>k</i>(<i>L</i>) representing the <i>k</i>-components of the flow depending on the scale of coarse-graining <i>L</i>. by Vladimir A. Andryushchenko (4662829)

Twenty-two identified and replicated loci and their overlap with associations to metabolic traits and clinical phenotypes. by Johannes Raffler (793347)

“…We added their proxy variants in LD (r² ≥ 0.8; based on 1000 genomes project data [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref050" target="_blank">50</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref051" target="_blank">51</a>]). …”

Aged-Related Changes in Body Composition and Association between Body Composition with Bone Mass Density by Body Mass Index in Chinese Han Men over 50-year-old by Ying Jiang (5910)

“…</p><p>Conclusions</p><p>These data indicate that LMI and FFMI exhibited significant negative associations with aging in Chinese Han males older than 50 years, whereas FMI had a positive association. …”

In vitro angiogenesis assay using Matrigel to characterize the antiangiogenic effect mediated by treatment scheme with topotecan and melphalan. by Ursula Winter (3145773)

The fluorescence emission spectra of dihydropyrimidinase. by Cheng-Yang Huang (741252)

“…<p>The decrease in intrinsic fluorescence of protein was measured at 334.5 nm upon excitation at 279 nm and 25°C with a spectrofluorimeter. …”

Loss of <i>FGR41</i> or <i>CWP419</i> does not impact susceptibility to cell wall stressors. by Andrew S. Wagner (11331477)

Overexpression of calcineurin effector genes does not restore calcium-induced masking in a <i>crz1Δ/Δ</i> mutant. by Andrew S. Wagner (11331477)

Effect of the seal resistance on circuit parameters. by Matej Hoťka (4610938)

“…The first event contained a step decrease of <i>R</i>_<i>Seal</i> from 100 to 10 GΩ while the second event contained a step change of <i>C</i>_<i>M</i> from 98.7 fF to 99.0 fF. …”

Silencing or suppression of TRPM7 inhibits cortical astrocyte proliferation. by Zhao Zeng (478844)

“…<p><b>A</b>. Representative images show the proliferation of astrocytes treated with control siRNA or TRPM7 siRNA. …”

House Dust Mite Allergen Regulates Constitutive Apoptosis of Normal and Asthmatic Neutrophils via Toll-Like Receptor 4 by Do Hyung Kim (739231)

Model of miRNA involvement in muscle response following BoNT/A-induced muscle paralysis. by Leah E. Worton (457030)

Loss of <i>FGR41</i> modestly delays hyphal development <i>in vitro</i>. by Andrew S. Wagner (11331477)

Aging in mouse tail skin leads to an aberrantly weak inflammatory signature with decreased expression of <i>Lyz1</i>, <i>Lyz2</i>, <i>Clec7a</i>, <i>Cd48</i>, <i>Tyrobp</i> and <i>... by William R. Swindell (175427)

Venn diagram representing the RNA sequencing results. by Shyamasree De Majumdar (168216)

TRPM7 is down-regulated in mouse cortical astrocytes by siRNA. by Zhao Zeng (478844)

“…<p><b>A</b>. RT-PCR shows that transfection of astrocytes with specific TRPM7 siRNA decreases the mRNA level of TRPM7 compared to those with control siRNA. …”