4 EC Performance on Structural Genomics test set. by Eric Venner (235381)

<i>In silico</i> clinical trials suggest little efficacy for corticosteroids or DAMP inhibitors. by Cordelia Ziraldo (221649)

UCH-L5 regulates inflammasome activity in chicken macrophages. by Evangel Kummari (719636)

“…</b> UCH-L5 was overexpressed in HD11 macrophages (UCH-L5) and empty vector was used as a control (ctrl). 24-hours past overexpression, the cells were subjected to <i>Salmonella</i> infection at MOI of 50:1 for 18-hours (inf) or left uninfected. …”

PI3Ks regulate plaque morphology and early protein production. by Shannon McNulty (248670)

“…<p><b>A.</b> PI3K inhibitors reduce plaque size in BSC40 cells. …”

Y-27632 mediated signal transduction during differentiation. by Roman J. Krawetz (309735)

“…<p>Total mRNA collected from all groups was converted to cDNA and probed to assay levels of β-catenin (A). β-catenin levels increased under all differentiation induction conditions, however, levels decreased significantly when Y-27632 was added during mesodermal and ectodermal differentiation. …”

Effect of aspirin on endometrial histomorphometry in PCOS rats during the window of implantation. by Ying Zhang (40767)

“…(HE staining, scare bar = 50μm). <b>(a)</b> Control group, the endometrial stroma is loose, with synchronous development of glands and stroma, abundant glands, and a rich vascular supply; <b>(b)</b> Model group, endometrial glandular hypoplasia is observed, characterized by small glandular lumina and a reduced number of glands, along with a decrease in vascularity; <b>(c)</b> Aspirin group, endometrial development shows improvement, manifested by larger glandular lumina, loose stroma, and an increased number of glands and vessels within the stroma. …”

SINGLE PORT LAPAROSCOPIC CHOLECYSTECTOMY: TECHNICAL ASPECTS AND RESULTS by Murillo de Lima FAVARO (5670416)

“…The mean surgical time was 67.97 min, showing a marked decrease when was reached close to 50 cases and a stabilization after 100 surgeries. …”

Increased TCR avidity of memory CD4+ T cells in HIV controllers. by Benoît Vingert (252525)

“…<p>(A) The TCR avidity of Gag293-specific CD4+ T cells was determined by MHC class II tetramer staining in the presence of decreasing tetramer concentrations. …”

Sensitivity to starvation increases after knockdown of sNPF and DTK in neurosecretory cells. by Lily Kahsai (233920)

“…<b>C</b> Kurs 6-driven knockdown of DTK produces strongly diminished survival at starvation (about 12 h decrease at 50% survival) (P<0.001, Log-rank test; for each genotype n = 224–229).…”

Perifosine targets the Aldefluor-positive cell population in breast cancer xenografts. by Hasan Korkaya (159560)

“…<p>(A–C). 50,000 cells from SUM159 cell line or two breast cancer xenografts, MCI, or UM2 were injected into NOD/SCID mice and the tumor size was monitored. …”

Box plots showing the distribution of cell sizes and phase durations under the assumption of CDKA/B:CYCB over-expression (OE), wild-type expression (WT), and under-expression (UE). by Daniel Williamson (2869301)

“…<p>Wild-type had default parameter values, over-expression a 50% increase in CDKA/B:CYCB synthesis rate and under-expression a 20% decrease. …”

Box plots showing the distribution of cell sizes and phase durations under the assumption of CDKA:CYCD over-expression (OE), wild-type expression (WT), and under-expression (UE). by Daniel Williamson (2869301)

“…<p>Wild-type had default parameter values, over-expression a 50% increase in CDKA:CYCD synthesis rate and under-expression a 20% decrease. …”

Reduced Lateral Mobility of Lipids and Proteins in Crowded Membranes by Joseph E. Goose (401716)

“…The increase in protein concentration also resulted in a decrease in the anomalous diffusion exponent α of the lipid. …”

Efficient inhibition of EGFP expression by zebrafish mir-30e precursor <i>in vivo</i>. by Mei Dong (157261)

“…The capped EGFP sensor mRNAs were co-injected with either miR-30e or miR-155 precursor mRNAs into one-cell stage embryos (B, bottom). (C) A dramatic decrease of EGFP fluorescence in 24 hpf embryos co-injected with EGFP-2×PT^mir30e sensor (10 pg) and miR-30e precursor (50 pg). …”

SOCS-1 silencing enhances cytokine production and stimulatory capacity of mo-DCs. by Meenakshi Sachdeva (817136)

“…Friedmann test was performed for comparisons between treated groups with pairwise comparisons using Dunn's multiple comparison adjustment for an overall p values <0.05. (a) Mo-DCs treated with siSOCS-1 had around 50% decrease in the expression of SOCS-1 gene which was significantly less than the control cells (p<0.05). …”

Image_4_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Image_5_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Image_3_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Image_1_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Data_Sheet_1_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.docx by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”