Isoindolin-1-ones Fused to Barbiturates: From Design and Molecular Docking to Synthesis and Urease Inhibitory Evaluation by Houman Kazemzadeh (12742141)

“…In vitro urease inhibitory results indicated that all the compounds had higher inhibitory activity than the standard inhibitor, thiourea, and compound <b>5b</b> proved to be the most potent inhibitor (IC₅₀ = 0.82 ± 0.03 μM). A molecular docking study was performed to understand the interaction between compounds <b>5a–n</b> and Jack bean urease enzyme. …”

Table_1_Porcine Invariant Natural Killer T Cells: Functional Profiling and Dynamics in Steady State and Viral Infections.DOCX by Alexander Schäfer (193561)

Table_1_Immunotherapy With Recombinant Alt a 1 Suppresses Allergic Asthma and Influences T Follicular Cells and Regulatory B Cells in Mice.docx by Juan Liu (6492)

“…</p>Methods<p>We synthesized and purified rAlt a 1. Alternaria-sensitized and challenged mice received subcutaneous immunotherapy (SCIT) with four different rAlt a 1 dosages (5, 50, 100, and 150 µg) or PBS only. …”

Image_1_Immunotherapy With Recombinant Alt a 1 Suppresses Allergic Asthma and Influences T Follicular Cells and Regulatory B Cells in Mice.tif by Juan Liu (6492)

“…</p>Methods<p>We synthesized and purified rAlt a 1. Alternaria-sensitized and challenged mice received subcutaneous immunotherapy (SCIT) with four different rAlt a 1 dosages (5, 50, 100, and 150 µg) or PBS only. …”

Image_2_Immunotherapy With Recombinant Alt a 1 Suppresses Allergic Asthma and Influences T Follicular Cells and Regulatory B Cells in Mice.tif by Juan Liu (6492)

“…</p>Methods<p>We synthesized and purified rAlt a 1. Alternaria-sensitized and challenged mice received subcutaneous immunotherapy (SCIT) with four different rAlt a 1 dosages (5, 50, 100, and 150 µg) or PBS only. …”

GFP+ NPC Implant Apoptosis. Implants were sectioned and immunostained for the early effector caspase, cleaved caspase-3 (red, GFP = green, DAPI = blue) and area of fluorescence rel... by Cicely Williams (291856)

“…<p>This initially higher rate of apoptosis significantly decreased by day 5 (0.036±0.050, p = 0.0063) to a rate comparable to that of the NPC∶BEC implants. …”

Study on the Effects of Nonelectrolyte Additives on the Phase, Thermodynamics, and Structural Changes in Micelles of Silicone Surfactants in Aqueous Solutions from Surface Activity... by Saurabh S. Soni (1708960)

“…The influence of given additive on the micellization of silicone surfactants was monitored from the changes in the free energy of micellization values for the surfactant solutions in water and water + additives. The cloud points and the critical micelle concentration values for the surfactant solutions were found to be decreased in the presence of the selected three additives. …”

<i>In silico</i> screening identifies doxazosin as a novel agonist for EphA2 receptor. by Aaron Petty (143170)

“…Note decreasing amount of EphA2 following ephrin-A1 and doxazosin treatment. …”

SFN suppressed HCV protein expression and RNA replication. by Jung-Sheng Yu (3214659)

The D₂/D₃ dopaminergic antagonist sulpiride significantly reduced sensory responses to tactile stimuli measured in the tentacle nerve (TN). by Jeffrey W. Brown (252683)

Brief group-delivered motivational interviewing is equally effective as brief group-delivered cognitive-behavioral therapy at reducing alcohol use in risky college drinkers by Cristina Martín-Pérez (8107928)

“…Alcohol use decreased in both groups at the 3- and 6-months measurement points (relative to baseline). …”

Leptin increases metabolic rate and raises RER. by David J. DiSilvestro (2602300)

CRISPR-Cas9-mediated mutation analysis of T₀ Stmc7 mutants. by Bikram Poudel (15989201)

Combined treatments with phosphatidylserine elevates IKAP protein level more efficiently than either drug alone. by Sivan Yannai (3594626)

Confocal laser microscopy of non-infected and persistently CDV-Ond infected DH82 cells. by Vanessa Maria Pfankuche (3375392)

DataSheet_2_IKZF1plus is a frequent biomarker of adverse prognosis in Mexican pediatric patients with B-acute lymphoblastic leukemia.docx by Joaquin Garcia-Solorio (18296686)

“…A decrease in OS was found in IKZF1^MUT and CDKN2A/2B^MUT patients, but the significance was lost after IKZF1^plus was removed.…”

DataSheet_1_IKZF1plus is a frequent biomarker of adverse prognosis in Mexican pediatric patients with B-acute lymphoblastic leukemia.xlsx by Joaquin Garcia-Solorio (18296686)

“…A decrease in OS was found in IKZF1^MUT and CDKN2A/2B^MUT patients, but the significance was lost after IKZF1^plus was removed.…”

Combinatorial treatment increases IKAP levels in human cells generated from Familial Dysautonomia patients by Sivan Yannai (3594626)

“…<div><p>Familial Dysautonomia (FD) is an autosomal recessive congenital neuropathy that results from a point mutation at the 5’ splice site of intron 20 in the <i>IKBKAP</i> gene. …”

<i>Kif15</i> deficient mice exhibit both depressive and manic behaviors in adulthood. by Xiaomei He (795333)

The expression of PAX7 and MYOD1 correlate with differential expression of diverse chemokines in HuMuSC. by Katharine Striedinger (15503387)

“…<p><b>(a)</b> Quantification of protein expression for PAX7+ and MYOD1 positive HuMuSC at day 0, 3 and 6 in vitro, showing an inverse correlation as progressively PAX7 expression decreases and MYOD1 expression increases in HuMuSC as they activate <i>in vitro</i>. …”