The COPI-Mediated Retrograde Trafficking Pathway Is a Negative Regulator of Lipid Storage by Mathias Beller (269148)

Heparinase treatment ablated daily oscillations in Aβ42 phagocytosis in macrophages. by Gretchen T. Clark (12071965)

“…Each cell sampled per time point is represented by a black or gray dot with the mean shown as a red diamond. …”

A 15-gene classifier can predict radiation dose levels in mice. by Joseph Lucas (104191)

“…While IGH-6 expression decreased in response to irradiation, LOXL1 expression increased promptly and CDKN1A was a late responsive gene.…”

A Hypomorphic Lsd1 Allele Results in Heart Development Defects in Mice by Thomas B. Nicholson (406800)

“…While there is evidence that Lsd1-interacting proteins regulate the activity and specificity of Lsd1, the significance and roles of such interactions in developmental processes remain largely unknown. Here we describe a hypomorphic Lsd1 allele that contains two point mutations in the tower domain, resulting in a protein with reduced interaction with known binding partners and decreased enzymatic activity. …”

The kinetics of the linear component affect the peak frequency of a bell shaped response. by Patrick A. Fletcher (583336)

“…(<b>B</b>) The corresponding bell-shaped responses have a peak that shifts to the right accordingly. (<b>C</b>) Duration compensation: increasing τ_a shifts the response in </a><a>_on,∞ and its K crossing point to the right. …”

Supplementary file 1_Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in... by Grace Blest-Hopley (10663945)

“…</p>Results<p>Improvements were observed across several mental health measures: PTSD (PCL-5 scores decreased by 50%, p=0.010), depression (PHQ-9 scores decreased by 65%, p<0.001), and anxiety (STAI) scores decreased by 28%, p<0.001). …”

Supplementary file 2_Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in... by Grace Blest-Hopley (10663945)

“…</p>Results<p>Improvements were observed across several mental health measures: PTSD (PCL-5 scores decreased by 50%, p=0.010), depression (PHQ-9 scores decreased by 65%, p<0.001), and anxiety (STAI) scores decreased by 28%, p<0.001). …”

Box plots reflecting the change in the difference between the DPOAE and the noise floor at all frequencies in the right ear. by Jessica Paken (10677168)

Box plots reflecting the change in the difference between the DPOAE and the noise floor at all frequencies in the left ear. by Jessica Paken (10677168)

Image_2_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif by Qin Zeng (166641)

“…Since sorafenib is classified as an FDA-approved drug, it serves as a preliminary lead point for additional experimentation and may be a promising therapy for type 1 diabetes in humans.…”

Illustration of three simple scenarios of association between genotype and a bivariate phenotype. by Matthew Stephens (3815)

“…A) A variant associated with <i>weight</i> but not <i>height</i>. …”

Image_1_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif by Qin Zeng (166641)

“…Since sorafenib is classified as an FDA-approved drug, it serves as a preliminary lead point for additional experimentation and may be a promising therapy for type 1 diabetes in humans.…”

Inc exhibits key properties of a Cul3 adaptor in neurons in vivo. by Qiuling Li (390393)

“…<p><b>(A)</b> Co-immunoprecipitation of 3×FLAG-Inc and 3×FLAG-3×HA-Cul3 from male whole animal lysates. …”

Image_4_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif by Qin Zeng (166641)

“…Since sorafenib is classified as an FDA-approved drug, it serves as a preliminary lead point for additional experimentation and may be a promising therapy for type 1 diabetes in humans.…”

Associations between HbA1c levels and mortality and diabetes complications. by Haipeng Ma (6792266)

“…The risk increases steadily with increasing HbA1c levels, with no clear inflection point. D: RCS curves for CKD risk. …”

Image_6_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif by Qin Zeng (166641)

“…Since sorafenib is classified as an FDA-approved drug, it serves as a preliminary lead point for additional experimentation and may be a promising therapy for type 1 diabetes in humans.…”

Image_5_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif by Qin Zeng (166641)

“…Since sorafenib is classified as an FDA-approved drug, it serves as a preliminary lead point for additional experimentation and may be a promising therapy for type 1 diabetes in humans.…”

Image_3_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif by Qin Zeng (166641)

“…Since sorafenib is classified as an FDA-approved drug, it serves as a preliminary lead point for additional experimentation and may be a promising therapy for type 1 diabetes in humans.…”

RAINFALL REGIME ON FINE ROOT GROWTH IN A SEASONALLY DRY TROPICAL FOREST by EUNICE MAIA DE ANDRADE (4894216)

“…The fine root biomass in July 2015 was 7.7±5.0 Mg ha-1 and the length was 5.0±3.2 km m-2. Fine root growth in SDTF is strongly limited by dry periods, occurring decreases in biomass and length of fine roots in all layers evaluated. …”

Is urotherapy alone as effective as a combination of urotherapy and biofeedback in children with dysfunctional voiding? by Adem Altunkol (5912324)