Resveratrol induces senescence through activation of p53, p21^CIP1 and p16^INK4A. by Mehtap Kilic Eren (591048)

Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo by Zhiqiang Li (102723)

“…Treatment of such diseases with small-molecule NIK inhibitors is a reasonable but underexplored approach. In this paper, we reported the discovery of a potent and selective NIK inhibitor <b>46</b> (XT2). …”

Crz1 mediates masking in response to exogenous calcium. by Andrew S. Wagner (11331477)

Aberrant CpG methylation of the <i>TFAP2A</i> gene constitutes a mechanism for loss of <i>TFAP2A</i> expression in human metastatic melanoma by Andrea R Hallberg (686570)

“…During melanocyte transformation and melanoma progression the expression profile of many genes changes. Among these, a gene implicated in several steps of melanocyte development, <i>TFAP2A</i>, is frequently silenced; however, the molecular mechanism of <i>TFAP2A</i> silencing in human melanoma remains unknown. …”

The functions <i>G</i>_<i>k</i>(<i>L</i>) representing the <i>k</i>-components of the flow depending on the scale of coarse-graining <i>L</i>. by Vladimir A. Andryushchenko (4662829)

Twenty-two identified and replicated loci and their overlap with associations to metabolic traits and clinical phenotypes. by Johannes Raffler (793347)

“…We added their proxy variants in LD (r² ≥ 0.8; based on 1000 genomes project data [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref050" target="_blank">50</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref051" target="_blank">51</a>]). …”

Impact of social isolation by Coronavirus disease 2019 in food: a narrative review by Luísa Harumi MATSUO (10351001)

“…A decrease in fish consumption and an increase in comfort foods were also reported. …”

Aged-Related Changes in Body Composition and Association between Body Composition with Bone Mass Density by Body Mass Index in Chinese Han Men over 50-year-old by Ying Jiang (5910)

“…</p><p>Conclusions</p><p>These data indicate that LMI and FFMI exhibited significant negative associations with aging in Chinese Han males older than 50 years, whereas FMI had a positive association. …”

HDX profile changes of βarr2 upon co-incubation with C7pp2. by Jeong Seok Ji (22008582)

In vitro angiogenesis assay using Matrigel to characterize the antiangiogenic effect mediated by treatment scheme with topotecan and melphalan. by Ursula Winter (3145773)

The fluorescence emission spectra of dihydropyrimidinase. by Cheng-Yang Huang (741252)

“…<p>The decrease in intrinsic fluorescence of protein was measured at 334.5 nm upon excitation at 279 nm and 25°C with a spectrofluorimeter. …”

Estimating Missing Unit Process Data in Life Cycle Assessment Using a Similarity-Based Approach by Ping Hou (17213)

“…We use the ecoinvent 3.1 unit process data sets to test our method in four steps: (1) dividing the data sets into a training set and a test set; (2) randomly removing certain numbers of data in the test set indicated as missing; (3) using similarity-weighted means of various numbers of most similar processes in the training set to estimate the missing data in the test set; and (4) comparing estimated data with the original values to determine the performance of the estimation. …”

Multi-omics Investigation into the Mechanism of Action of an Anti-tubercular Fatty Acid Analogue by Isin T. Sakallioglu (1978903)

“…The metabolomics results showed that DA-CB has a general MoA related to that of ethionamide (ETH), a mycolic acid inhibitor that targets enoyl-ACP reductase (InhA), but DA-CB likely inhibits a step downstream from InhA. …”

Loss of <i>FGR41</i> or <i>CWP419</i> does not impact susceptibility to cell wall stressors. by Andrew S. Wagner (11331477)

Overexpression of calcineurin effector genes does not restore calcium-induced masking in a <i>crz1Δ/Δ</i> mutant. by Andrew S. Wagner (11331477)

Flow chart of study participants. by Eva Rydahl (6260771)

“…This study aims to evaluate the impact of a 12-step initiative implemented by a Danish tertiary hospital, targeting organisational structures, healthcare personnel, and the birthing population, on reducing cesarean section rates, compared to control hospitals that did not adopt a similar approach.…”

Absolute numbers among CS groups. by Eva Rydahl (6260771)

“…This study aims to evaluate the impact of a 12-step initiative implemented by a Danish tertiary hospital, targeting organisational structures, healthcare personnel, and the birthing population, on reducing cesarean section rates, compared to control hospitals that did not adopt a similar approach.…”

Simple Scalable Fabrication of Laser-Induced Graphene Composite Membranes for Water Treatment by Abhishek Gupta (402938)

“…This work demonstrates a method to scale up LIG composite membranes, a crucial step that is necessary in determining their commercial potential in water technology applications.…”

Simple Scalable Fabrication of Laser-Induced Graphene Composite Membranes for Water Treatment by Abhishek Gupta (402938)

“…This work demonstrates a method to scale up LIG composite membranes, a crucial step that is necessary in determining their commercial potential in water technology applications.…”

Flow of <i>M</i>. <i>bovis</i> antigen selection for use in the Luminex immunoassay development. by Charlotte Moens (17118225)