Psychosine-induced changes vimentin in human astrocytes and is partially reversed by DEDA. by Cedric Misslin (4567393)

Adult schistosome motility and egg production are differentially affected by the nine N-acyl homoserine lactones. by Helen Whiteland (6743339)

Co-transformed cells secrete cytokines that can support their growth through JAK/STAT signaling. by Mitchell Hayes (5334887)

The lack of Nrf2 does not affect PMN phagocytic capacity. by Doumet Georges Helou (7255823)

Semi-log plot of the total number of medals obtained by countries at Beijing (BJG) and London (LDN) recent Summer Olympic Games, as ranked according to their decreasing “order of i... by Marcel Ausloos (748325)

Semi-log plot of the number of Gold medals obtained by countries at Beijing (BJG) and London (LDN) recent Summer Olympic Games, as ranked according to their decreasing “order of im... by Marcel Ausloos (748325)

The Design, Synthesis, and Characterizations of Spore Germination Inhibitors Effective against an Epidemic Strain of Clostridium difficile by Shiv K. Sharma (1945762)

“…To circumvent this problem, a series of cholic acid amides were synthesized and tested against R20291. …”

Simulations of the model with adhesion-propulsion feedback. by Leonie van Steijn (10142786)

Simulations of the model showing different motility types. by Leonie van Steijn (10142786)

Fürth with translational diffusion fits MSD of model better than Fürth without translational diffusion. by Leonie van Steijn (10142786)

Downregulation of CD36 impaired phagocytic capacity and is associated with a proinflammatory phenotype of <i>Mst1</i> deficiency macrophages. by Jianyang Li (461703)

Interactive Model Implementation using Artistoo. by Leonie van Steijn (10142786)

Graphs of the dimensional changes of the lens from the 20-year-old donor. by Ronald A. Schachar (16674576)

Adhesion growth dynamics influence adhesion cluster size and localisation, cell speed and MSD. by Leonie van Steijn (10142786)

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously inhibit histone deacetylases (from a low nanomolar range) and DNA methyltransferase-1 (from a mid-nanomolar range, IC₅₀ < 200 nM). …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously inhibit histone deacetylases (from a low nanomolar range) and DNA methyltransferase-1 (from a mid-nanomolar range, IC₅₀ < 200 nM). …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously inhibit histone deacetylases (from a low nanomolar range) and DNA methyltransferase-1 (from a mid-nanomolar range, IC₅₀ < 200 nM). …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously inhibit histone deacetylases (from a low nanomolar range) and DNA methyltransferase-1 (from a mid-nanomolar range, IC₅₀ < 200 nM). …”

Schematic representation of the effect of adhesion on cell propulsion strength. by Leonie van Steijn (10142786)

Persistence times obtained from fitting MSD with Fürth with translational diffusion (Eq 2) against adhesion area for different values of <i>p</i>_<i>s</i> and λ<sub><i>ad... by Leonie van Steijn (10142786)