Video_4_Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7.AVI by Ana Dios-Esponera (6422411)

“…Lymphocyte homing to lymph nodes requires that they cross endothelial barriers present in blood vessels and lymphatics. This multi-step process requires a remodeling of the lymphocyte plasma membrane, which is mediated by the dynamic re-arrangement of the actin cytoskeleton. …”

Video_5_Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7.AVI by Ana Dios-Esponera (6422411)

“…Lymphocyte homing to lymph nodes requires that they cross endothelial barriers present in blood vessels and lymphatics. This multi-step process requires a remodeling of the lymphocyte plasma membrane, which is mediated by the dynamic re-arrangement of the actin cytoskeleton. …”

Video_6_Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7.AVI by Ana Dios-Esponera (6422411)

“…Lymphocyte homing to lymph nodes requires that they cross endothelial barriers present in blood vessels and lymphatics. This multi-step process requires a remodeling of the lymphocyte plasma membrane, which is mediated by the dynamic re-arrangement of the actin cytoskeleton. …”

Coarse-grained model leads to collective behavior. by Giovanna De Palo (476510)

“…The peak in susceptibility becomes higher the larger the number of cells, and NN distances decrease accordingly. Profiles in the inset were smoothed with a moving average filter spanning ten points. …”

Abnormal HRV responses after postural change in pSS patients by Fin ZJ Cai (51289)

“…The net result of a normal response to standing is very little change in LF HRV and a substantial decrease in high frequency HRV. …”

Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Density dependent growth modulates time-to-threshold and optimal antibiotic treatment for in-vitro growth model. by Jason Karslake (3233934)

“…Lower right inset: final population size (relative to the case with no density dependence) for the naïve treatment (red) and the optimal step-like treatment (blue) as a function of ε. At a given value of ε, density-dependence can significantly increase n(T) (magenta arrow), but the optimal step dosing can often reduce the effects by 50% or more (green arrow).…”

Table_2_Social Media and Large Carnivores: Sharing Biased News on Attacks on Humans.xlsx by Veronica Nanni (8613942)

“…Thus, constant engagement of scientists on social media would be needed to both disseminate more accurate information on large carnivores and stem the tide of misinformation before its widespread diffusion, a crucial step for effective predator conservation.…”

Table_1_Social Media and Large Carnivores: Sharing Biased News on Attacks on Humans.XLSX by Veronica Nanni (8613942)

“…Thus, constant engagement of scientists on social media would be needed to both disseminate more accurate information on large carnivores and stem the tide of misinformation before its widespread diffusion, a crucial step for effective predator conservation.…”

H3 K36 Methylation Helps Determine the Timing of Cdc45 Association with Replication Origins by Fiona Pryde (263331)

“…A pivotal step during this conversion is the binding of the replication factor Cdc45, which associates with replication origins at approximately their time of activation in a manner partially controlled by histone acetylation.…”

Data_Sheet_1_Stronger microbial nutrient limitations in subsoil along the precipitation gradient of agroecosystem: insights from soil enzyme activity and stoichiometry.PDF by Jingjing Yang (119262)

“…</p>Results and Discussion<p>We found that N- and P-acquiring enzymes have a tendency to decrease or increase, respectively, but C-acquiring enzymes did not change along the precipitation gradient throughout soil profiles. …”

DataSheet_1_Role of fronto-limbic circuit in neuropsychiatric symptoms of dementia: clinical evidence from an exploratory study.docx by Matteo Cotta Ramusino (5139764)

“…Apathy showed predominant involvement of the inferior frontal regions in AD group (a 30% decrease in CT) and of the cingulate cortex in non-AD group (a 50-60% decrease in CT). …”

Schematic illustration of the variable-ranking process for the derivation cohort. by Johan Nilsson (364438)

“…<p>Panel (A). Step I: training of the survival model using fivefold cross-validation and a committee machine with 10 members. …”

Data_Sheet_1_Finger-specific effects of age on tapping speed and motor fatigability.docx by Caroline Heimhofer (19735888)

“…</p>Methods<p>We collected finger tapping data in a field experiment from the general population with a smartphone app, and we investigated age differences in maximal tapping speed, as well as the decrease in tapping speed for the index, middle, and little fingers.…”

Dependence of the Conceptual Distance <i>d</i>(<i>N</i>) on Dataset Size for Different Document Removal Strategies. by Artem Chumachenko (21681455)

“…</p> <p>To demonstrate that the dynamics of the conceptual distance <i>d</i> for a given pair of concepts <i>A</i> and <i>B</i> is weakly influenced by the size of the data set <i>N</i> and the increasing number of background documents with zero concept frequencies, and that the primary driver of the decrease in conceptual distance is the number of documents mentioning both concepts <i>N</i>_<i>AB</i>, we present in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0327793#pone.0327793.s003" target="_blank">S2 Fig</a> the time series for key metrics observed for multiple pairs of concepts in the studied dataset. …”

FigShare Figure 1. Targetable pathogenic variants with prime editing. by John Morris (8904362)

“…<b>(a)</b> Total number of ClinVar pathogenic variants by mutation type (transition, transversion, insertion or deletion) (<i>left</i>) and the percentage targetable with prime editing after various filtering steps in the design pipeline (<i>right</i>). …”

Evaluation and risk communication of effects of alcohol exposure on disposable procedure masks and portable air purifiers by Yo Ishigaki (11052900)

Data_Sheet_1_Effect of Drought on the Methylerythritol 4-Phosphate (MEP) Pathway in the Isoprene Emitting Conifer Picea glauca.PDF by Erica Perreca (5977940)

“…However, under severe drought, as flux declined below detectable levels, DXS activity showed no significant decrease, indicating a much-reduced role in controlling flux under these conditions. …”

Dopamine depletion increases intrinsic excitability of medium spiny neurons. by Karima Azdad (370732)

“…(D) Summary histogram of the mean first spike latency at the 120 pA current pulse illustrating the decrease of the first spike latency induced by dopamine depletion. …”

Table_1_Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age.DOCX by Giulia Costa (166412)